Results 51 to 60 of about 288,709 (262)

An acyl-homoserine lactone acylase found in Stenotrophomonas maltophilia exhibits both quorum quenching activity and the ability to degrade penicillin antibiotics. [PDF]

Sci Rep
Bravo M, Conchillo-Solé Ò, Coves X, García-Navarro A, Gómez AC, Márquez-Martínez M, Ferrer-Miralles N, Daura X, Gibert I, Yero D.   +9 more
europepmc   +3 more sources

Development and Biochemical Characterization of Quorum Quenching Enzyme from Deep-Sea Bacillus velezensis DH82 [PDF]

Microorganisms
Sun X, Liu J, Yan Y, Yang S, Zhang G, Mohamed H.   +5 more
europepmc   +3 more sources

Quorum-Sensing Regulation of Antimicrobial Resistance in Bacteria

Microorganisms, 2020
Quorum sensing is a cell-to-cell communication system that exists widely in the microbiome and is related to cell density. The high-density colony population can generate a sufficient number of small molecule signals, activate a variety of downstream ...
Xihong Zhao, Zixuan Yu, Tian Ding
doaj   +1 more source

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

Advanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova, Fatemeh Ahmadi, Jennifer Cruickshank, Zheyuan Miao, David W. Cescon, Eugenia Kumacheva   +5 more
wiley   +1 more source

A mathematical model of quorum quenching in biofilm colonies and its potential role as an adjuvant for antibiotic treatment

Mathematics in Applied Sciences and Engineering, 2022
We extend a previously presented mesoscopic (i.e. colony scale) mathematical model of the reaction of bacterial biofilms to antibiotics. In that earlier model, exposure to antibiotics evokes two responses: inactivation as the antibiotics kill the ...
Maryam Ghasemi, Viktoria Freingruber, Christina Kuttler, Hermann J Eberl   +3 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

A novel stress response mechanism, triggered by indole, involved in quorum quenching enzyme MomL and iron-sulfur cluster in Muricauda olearia Th120

Scientific Reports, 2017
Indole, as a signal molecule, is involved in multiple physiological behavior including biofilm formation, antibiotic resistance and virulence. In this study, we demonstrated that indole was involved in iron deficient and H2O2 stress response in Muricauda
Yan Wang, Hui Li, Xinxin Cui, Xiao-Hua Zhang   +3 more
doaj   +1 more source

Artificial Symbiosis for Bulk Production of Bacterial Cellulose Composites

Advanced Materials, EarlyView.
Co‐cultivation of the cellulose‐producing bacterium with the microalga enables bulk formation of bacterial cellulose under static incubation, with photosynthetically active oxygen‐generating sites throughout the medium. This symbiotic platform supports 3D cellulosic constructs with geometries dictated by the vessel shape.
Kui Yu, Sing Teng Chua, Ran Zhao, Alyssa Smith, Michael Kühl, Alison G. Smith, Tom Ellis, Silvia Vignolini   +7 more
wiley   +1 more source

Engineering quorum quenching enzymes: progress and perspectives [PDF]

Biochemical Society Transactions, 2019
Abstract Quorum sensing is a key contributor to the virulence of many important plant, animal and human pathogens. The disruption of this signalling—a process referred to as ‘quorum quenching’—is a promising new approach for controlling microbial pathogens.
Shereen A. Murugayah, Monica L. Gerth
openaire   +2 more sources

Drugs for the Quorum Sensing Inhibition of Oral Biofilm: New Frontiers and Insights in the Treatment of Periodontitis

Pharmaceutics, 2022
Chemical molecules are used by microorganisms to communicate with each other. Quorum sensing is the mechanism through which microorganisms regulate their population density and activity with chemical signaling.
Alessandro Polizzi, Martina Donzella, Giada Nicolosi, Simona Santonocito, Paolo Pesce, Gaetano Isola   +5 more
doaj   +1 more source