Results 51 to 60 of about 281,005 (235)

A mathematical model of quorum quenching in biofilm colonies and its potential role as an adjuvant for antibiotic treatment

open access: yesMathematics in Applied Sciences and Engineering, 2022
We extend a previously presented mesoscopic (i.e. colony scale) mathematical model of the reaction of bacterial biofilms to antibiotics. In that earlier model, exposure to antibiotics evokes two responses: inactivation as the antibiotics kill the ...
Maryam Ghasemi   +3 more
doaj   +1 more source

Quorum-Sensing Regulation of Antimicrobial Resistance in Bacteria

open access: yesMicroorganisms, 2020
Quorum sensing is a cell-to-cell communication system that exists widely in the microbiome and is related to cell density. The high-density colony population can generate a sufficient number of small molecule signals, activate a variety of downstream ...
Xihong Zhao, Zixuan Yu, Tian Ding
doaj   +1 more source

Modification and Assembly of a Versatile Lactonase for Bacterial Quorum Quenching [PDF]

open access: yesMolecules, 2018
This work sets out to provide a self-assembled biopolymer capsule activated with a multi-functional enzyme for localized delivery. This enzyme, SsoPox, which is a lactonase and phosphotriesterase, provides a means of interrupting bacterial communication pathways that have been shown to mediate pathogenicity.
Rhoads, Melissa K.   +6 more
openaire   +4 more sources

A novel stress response mechanism, triggered by indole, involved in quorum quenching enzyme MomL and iron-sulfur cluster in Muricauda olearia Th120

open access: yesScientific Reports, 2017
Indole, as a signal molecule, is involved in multiple physiological behavior including biofilm formation, antibiotic resistance and virulence. In this study, we demonstrated that indole was involved in iron deficient and H2O2 stress response in Muricauda
Yan Wang   +3 more
doaj   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

open access: yesAdvanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi   +4 more
wiley   +1 more source

Drugs for the Quorum Sensing Inhibition of Oral Biofilm: New Frontiers and Insights in the Treatment of Periodontitis

open access: yesPharmaceutics, 2022
Chemical molecules are used by microorganisms to communicate with each other. Quorum sensing is the mechanism through which microorganisms regulate their population density and activity with chemical signaling.
Alessandro Polizzi   +5 more
doaj   +1 more source

The Role of Artificial Intelligence in Advancing Biosensor Technology: Past, Present, and Future Perspectives

open access: yesAdvanced Materials, EarlyView.
This review explores the transformative role of AI in biosensor technology and provides a holistic interdisciplinary perspective that covers a broader scope of AI‐enabled biosensor technologies across various sectors including healthcare, environmental monitoring, food safety, and agriculture. It also highlights the important role of novel materials in
Tuğba Akkaş   +4 more
wiley   +1 more source

Hosts and Commensal Bacteria Synergistically Antagonize Opportunistic Pathogens at the Single‐Cell Resolution

open access: yesAdvanced Science, EarlyView.
In the tripartite‐species model, Drosophila larvae stimulate lactate production through excreting digestion enzymes. S. marcescens population senses a cue of lactate and tends to diverge into virulent and reduced virulence subclusters with remarkable heterogeneity to metabolize carbon metabolism and counter colonization resistance, giving a fitness ...
Sheng Zhang   +10 more
wiley   +1 more source

Unlocking Lactonase Enzymes as Biocatalysts for the Deracemisation of Chiral γ‐Thiolactones

open access: yesAngewandte Chemie, Volume 137, Issue 29, July 14, 2025.
The application of lactonase enzymes as biocatalysts still remains underexplored. This study discloses the biocatalytic activity of two lactonases in the deracemisation of chiral C3‐substituted‐γ‐thiolactones. The biocatalyst GcL catalyses the enzymatic kinetic resolution (EKR) of C3‐amide‐thiolactones, while the rationally engineered biocatalyst N9 ...
Jingyue Wu   +7 more
wiley   +2 more sources

Quorum quenching activity of Andrographis paniculata (Burm f.) Nees andrographolide compounds on metallo-β-lactamase-producing clinical isolates of Pseudomonas aeruginosa PA22 and PA247 and their effect on lasR gene expression

open access: yesHeliyon, 2021
Andrographis paniculata (Burm f.) Nees is a tropical plant native to Southeast Asia that has been used as an effective remedy for a wide variety of illnesses in traditional Chinese and Ayurvedic medicine.
An Margarete Tan Lim   +5 more
doaj  

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