Results 121 to 130 of about 101,100 (329)

Unlocking Lactonase Enzymes as Biocatalysts for the Deracemisation of Chiral γ‐Thiolactones

Angewandte Chemie, EarlyView.
The application of lactonase enzymes as biocatalysts still remains underexplored. This study discloses the biocatalytic activity of two lactonases in the deracemisation of chiral C3‐substituted‐γ‐thiolactones. The biocatalyst GcL catalyses the enzymatic kinetic resolution (EKR) of C3‐amide‐thiolactones, while the rationally engineered biocatalyst N9 ...
Jingyue Wu, Michele Crotti, Ivan Bassanini, Mahdi Hassankalhori, Erica Elisa Ferrandi, Ferran Sancho, Daniela Monti, Daniele Castagnolo   +7 more
wiley   +2 more sources

Comprehensive insights into UTIs: from pathophysiology to precision diagnosis and management

Frontiers in Cellular and Infection Microbiology
Urinary tract infections (UTIs) are the second most common infectious disease, predominantly impacting women with 150 million individuals affected globally.
Swathi Sujith, Adline Princy Solomon, John Bosco Balaguru Rayappan   +2 more
doaj   +1 more source

Interference With Quorum-Sensing Signal Biosynthesis as a Promising Therapeutic Strategy Against Multidrug-Resistant Pathogens

Frontiers in Cellular and Infection Microbiology, 2019
Faced with the global health threat of increasing resistance to antibiotics, researchers are exploring interventions that target bacterial virulence factors.
Osmel Fleitas Martínez, Osmel Fleitas Martínez, Pietra Orlandi Rigueiras, Állan da Silva Pires, William Farias Porto, William Farias Porto, William Farias Porto, Osmar Nascimento Silva, Cesar de la Fuente-Nunez, Cesar de la Fuente-Nunez, Cesar de la Fuente-Nunez, Cesar de la Fuente-Nunez, Cesar de la Fuente-Nunez, Octavio Luiz Franco, Octavio Luiz Franco, Octavio Luiz Franco   +15 more
doaj   +1 more source

Glucose‐Responsive and Analgesic Gel for Diabetic Subcutaneous Abscess Treatment by Simultaneously Boosting Photodynamic Therapy and Relieving Hypoxia

Advanced Science, EarlyView.
The work constructs a glucose‐triggered gel for diabetic abscess treatment. The results demonstrate that the gel catalyzes glucose into oxygen, alleviates the hypoxia, and ensures sufficient ROS generation to combat pathogenic bacteria. Simultaneously, borneol within the gel can enhance the antibacterial activity of ROS and alleviate pain in patients ...
Bin Huang, Honglin An, Jianfeng Chu, Shiqi Ke, Jing Ke, Yiman Qiu, Jieping Zhang, Hanqi Zhu, Jiahui Lin, Minguang Yang, Dongliang Yang, Xuejiao Song, Weilin Liu   +12 more
wiley   +1 more source

Mean-field equation for a stochastic many-particle model of quorum-sensing microbial populations

, 2018
We prove a mean-field equation for the dynamics of quorum-sensing microbial populations. In the stochastic many-particle process, individuals of a population produce public good molecules to different degrees.
Frey, Erwin, Knebel, Johannes, Pickl, Peter   +2 more
core  

From Ancient Techniques to Modern Solutions: In Situ Synthesis of C‐S‐H for Sandstone Conservation

Advanced Science, EarlyView.
Herein, this work presents a paleo‐inspired approach to synthesizing and optimizing C‐S‐H‐based grouting mortars for conserving the sandstone of Beishan Grottoes, Dazu Rock Carvings, China. By achieving an optimal recipe compatible with natural sandstone, this work demonstrates the pivotal role of hydrogen bonding in the adhesion between C‐S‐H mortars ...
Mengjun Jia, Huimin Yan, Qingqing Xu, Celestino Grifa, Gang Zhao, Siwei Jiang, Jinhua Wang, Zhenhua Wei, Han Liu, Xiao Ma   +9 more
wiley   +1 more source

Quorum sensing intervened bacterial signaling: Pursuit of its cognizance and repression

Journal of Genetic Engineering and Biotechnology, 2018
Bacteria communicate within a system by means of a density dependent mechanism known as quorum sensing which regulate the metabolic and behavioral activities of a bacterial community.
Kayeen Vadakkan, Abbas Alam Choudhury, Ramya Gunasekaran, Janarthanam Hemapriya, Selvaraj Vijayanand   +4 more
doaj  

Correlated Phenotypic Transitions to Competence in Bacterial Colonies

, 2007
Genetic competence is a phenotypic state of a bacterial cell in which it is capable of importing DNA, presumably to hasten its exploration of alternate genes in its quest for survival under stress.
A. Goldebeter, B. A. Lazazzera, Eshel Ben-Jacob, Herbert Levine, Inbal Hecht, M. B. Elowitz   +5 more
core   +1 more source

Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators [PDF]

, 1994
W. Claiborne Fuqua, Stephen C. Winans, E. Peter Greenberg   +2 more
openalex   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

Advanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen, Xiaokang Ma, Longlin Zhang, Hao Li, Jichang Zheng, Shengru Wu, Ke Zuo, Yulong Yin, Jing Wang, Bie Tan   +9 more
wiley   +1 more source