An Investigation of Quorum Sensing Inhibitors against Bacillus cereus in The Endophytic Fungus Pithomyces sacchari of the Laurencia sp. [PDF]
Mar DrugsXiang SL, Xu KZ, Yin LJ, Jia AQ.
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Flexible Fragment Growing Boosts Potency of Quorum-Sensing Inhibitors against Pseudomonas aeruginosa Virulence. [PDF]
ChemMedChem, 2020 Zender M +10 more
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Natural Products as Quorum Sensing Inhibitors
Natural Product CommunicationsCrist N. Filer
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Discovery and evaluation of 3-(2-isocyanobenzyl)-1<i>H</i>-indole derivatives as potential quorum sensing inhibitors for the control of <i>Pseudomonas aeruginosa</i> infections <i>in vitro</i>. [PDF]
RSC Med ChemWang J +7 more
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Quorum Sensing Inhibitors: An Overview
Biotechnology Advances, 2013Excessive and indiscriminate use of antibiotics to treat bacterial infections has lead to the emergence of multiple drug resistant strains. Most infectious diseases are caused by bacteria which proliferate within quorum sensing (QS) mediated biofilms.
Vipin Chandra Kalia
exaly +3 more sources
A clash of quorum sensing vs quorum sensing inhibitors: an overview and risk of resistance
Archives of Microbiology, 2023Indiscriminate use of antibiotics to treat microbial pathogens has caused emergence of multiple drug resistant strains. Most infectious diseases are caused by microbes that are capable of intercommunication using signaling molecules, which is known as quorum sensing (QS). Such pathogens express their pathogenicity through various QS-regulated virulence
Rohit Patel +6 more
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Quorum sensing of pathogenic bacteria and quorum-sensing inhibitors
Chinese Science Bulletin, 2012The emergence of antibiotic-resistant and especially multidrug-resistant pathogenic bacteria intensifies the need to screen new drug targets and develop new antibacterial drugs. Bacteria coordinate their virulent behaviors in a cell density-dependent manner known as quorum sensing (QS).
ZongHui YUAN +4 more
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Inhibitors and antagonists of bacterial quorum sensing
Medicinal Research Reviews, 2008AbstractBacteria can regulate community‐wide behaviors including biofilm formation, virulence, conjugation, sporulation, and swarming motility through a process called quorum sensing. Inhibitors and antagonists of bacterial quorum sensing are important research tools and potential therapeutic agents.
Nanting, Ni +3 more
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Quorum sensing inhibitors: a patent overview
Expert Opinion on Therapeutic Patents, 2009Quorum sensing (QS) is a microbial cell-cell signaling system that correlates gene expression with cell population density. It plays important roles in intra-species communications and is also involved in inter-species and microbe-host interactions. Because QS controls a wide spectrum of phenotypes including virulence and biofilm formation, inhibition ...
Jiachuan, Pan, Dacheng, Ren
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Dihydropyrrolones as bacterial quorum sensing inhibitors
Bioorganic & Medicinal Chemistry Letters, 2019Bacteria regulate their pathogenicity and biofilm formation through quorum sensing (QS), which is an intercellular communication system mediated by the binding of signaling molecules to QS receptors such as LasR. In this study, a range of dihydropyrrolone (DHP) analogues were synthesized via the lactone-lactam conversion of lactone intermediates.
Basmah Almohaywi +8 more
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