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Dietary phytochemicals as quorum sensing inhibitors
Fitoterapia, 2007Quorum sensing (QS) is a cell density dependent expression of species in bacteria mediated by hormone like compounds called autoinducers (AI). Several processes responsible for successful establishment of bacterial infection are mediated by QS. Inhibition of QS is therefore being considered as a new target for antimicrobial chemotherapy.
D A, Vattem +3 more
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Quorum Sensing Inhibitors as Antipathogens: Biotechnological Applications
Biotechnology Advances, 2019The mechanisms through which microbes communicate using signal molecules has inspired a great deal of research. Microbes use this exchange of information, known as quorum sensing (QS), to initiate and perpetuate infectious diseases in eukaryotic organisms, evading the eukaryotic defense system by multiplying and expressing their pathogenicity through ...
Yun Chan Kang +2 more
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Nanomaterials as Quorum Sensing Inhibitors
2020Nano scale materials have unique physicochemical and optical properties due to their small particle size. They are finding increased application in the field of therapeutics and diagnostics. The antimicrobial properties of nanomaterials have been well investigated.
Jamuna A. Bai, V. Ravishankar Rai
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Quorum Sensing Inhibitors as Therapeutics: Bacterial Biofilm Inhibition
Bioorganic Chemistry, 2023The overuse and inappropriate use of antibiotics to treat bacterial infections has led to the development of multiple drug resistant strains. Biofilm is a complex microorganism aggregation defined by the presence of a dynamic, sticky, and protective extracellular matrix made of polysaccharides, proteins, and nucleic acids.
Ashok K Yadav +2 more
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Biofilm and Quorum Sensing inhibitors: the road so far
Expert Opinion on Therapeutic Patents, 2020Biofilm is a complex aggregation of microorganisms characterized by the presence of a dynamic, adhesive and protective extracellular matrix composed of polysaccharides, proteins and nucleic acids. It is estimated that the vast majority of human infections are related to the biofilm in which the microorganisms reside and communicate with each other ...
Carradori S. +5 more
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Quorum Sensing Inhibitors as Anti-Biofilm Agents
Current Pharmaceutical Design, 2014Biofilms are microbial sessile communities characterized by cells that are attached to a substratum or interface or to each other, are embedded in a self-produced matrix of extracellular polymeric substances and exhibit an altered phenotype compared to planktonic cells.
Gilles, Brackman, Tom, Coenye
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Quorum sensing inhibitors: a patent review
Expert Opinion on Therapeutic Patents, 2013Quorum sensing (QS) is a cell-to-cell communication that regulates gene expression and coordinates their behavior in accordance with the cell population density as a result of discerning molecules termed autoinducers (AIs). The processes that QS governed include biofilm formation, bacterial virulence, antibiotic production, competence, conjugation ...
Tianyu, Jiang, Minyong, Li
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Fungal Quorum Sensing Inhibitors
2014Adaptation to various ecosystems is important to all microbes for growth and survival. Pathogenic microbes, especially bacteria, have developed mechanisms of synchronised expression of virulence genes with increasing population density through quorum sensing, enabling their survival in various host organisms.
Rohit Sharma, Kamlesh Jangid
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Microbial Pathogenesis, 2017
Antimicrobial therapy against extensively drug-resistant (XDR) P. aeruginosa biofilms is less efficient compared to the treatment of equal bacterial counts of free-floating planktonic cells, which has become a serious threat in hospital environment. P.
Ellappan, Kalaiarasan +5 more
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Antimicrobial therapy against extensively drug-resistant (XDR) P. aeruginosa biofilms is less efficient compared to the treatment of equal bacterial counts of free-floating planktonic cells, which has become a serious threat in hospital environment. P.
Ellappan, Kalaiarasan +5 more
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ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Weng C, Chan +2 more
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AbstractFor Abstract see ChemInform Abstract in Full Text.
Weng C, Chan +2 more
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