Results 111 to 120 of about 17,031,818 (292)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

R&D-Productivity Dynamics: Causality, Lags, and "Dry Holes" [PDF]

We study four issues in R&D–productivity dynamics: does R&D Granger cause productivity, is there a lag between R&D and its productivity effects, does the potency of R&D vary in timing and magnitude, and what is the role of R&D spillovers and aggregate ...
Petri Rouvinen
core  

Environmental regulation, R&D subsidies, and industrial green total factor productivity

Sustainable Futures
In the face of worsening global environmental degradation, significant attention has been devoted to the greening of industrial transformation and development, specifically by improving industrial green total factor productivity (GTFP).
Bu Wei, Li Chenxi, Liu Shanshan
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

R&D inputs and productivity growth in China [PDF]

The relationship between investment in R&D and productivity growth have been well documented in the literature. So far little research has been done on this topic for China, in part due to data limitations.
Zheng, Yan
core   +1 more source

RFAC, a program for automated NMR R-factor estimation [PDF]

, 2000
A computer program (RFAC) has been developed, which allows the automated estimation of residual indices (R-factors) for protein NMR structures and gives a reliable measure for the quality of the structures.
Gronwald, W., Ganslmeier, B., Kirchhöfer, R., Kalbitzer, Hans Robert, Kremer, W., Neidig, K.-P., Görler, A.   +6 more
core  

Factor-Augmenting Technical Change: an Empirical Assessment [PDF]

This paper estimates factor-specific technical change and input substitution using a structural approach. It improves upon the existing literature by introducing technology drivers for factor productivities and by assessing the impact of endogenous ...
Carlo Carraro, Enrica De Cian
core   +3 more sources

Modeling of the Rainfall and R-Factor for Tocantins State, Brazil

Revista Brasileira de Ciência do Solo
The state of Tocantins is inserted in the new Brazilian agricultural frontier and has shown enormous potential for expansion of the agricultural lands.
Junior Cesar Avanzi, Marcelo Ribeiro Viola, Carlos Rogério de Mello, Marcos Vinicius Giongo, Lucas Machado Pontes   +4 more
doaj   +1 more source

Ecology of R Factors

South African Medical Journal, 2017
The resistance to antimicrobial drugs and the incidence of R factors were determined in coliform bacteria, isolated from stool and environmental (soil, water) specimens from an urban Xhosa community, as well as from a remote drug-frea Xhosa community in the Transkei.
Marcos, D, Woods, DR
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source