Results 71 to 80 of about 17,969,489 (257)

Integration decision matrix R.

, 2018
Integration decision matrix R.
Xinli You (1476334), Peide Liu (3684517)
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Optimizing degassing for particle-reinforced Al composite: Advanced ultrasonic-assisted argon treatment and numerical simulation insights

Ultrasonics Sonochemistry
Hydrogen removal from particle-reinforced Al composite is critical for preventing porosities near particle clusters and improving comprehensive material properties.
Jian Chen, Xinyuan Jin, Jiwei Geng, Xianhui Luo, Yugang Li, Peikang Xia, Xianfeng Li, Fangming Wang, Dong Chen, Mingliang Wang, Haowei Wang   +10 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

On generating correlated random variables with a given valid or invalid Correlation matrix [PDF]

In simulation we often have to generate correlated random variables by giving a reference intercorrelation matrix, R or Q. The matrix R is positive definite and a valid correlation matrix.
Mishra, SK
core  

On a matrix group constructed from an {R,s+1,k}-potent matrix [PDF]

, 2014
Let R∈C^(n×n) be a {k}-involutory matrix (that is, R^k=I_n) for some integer k≥2, and let s be a nonnegative integer. A matrix A∈C^(n×n) is called an {R,s+1,k}-potent matrix if A satisfies R A = A^(s+1) R. In this paper, a matrix group corresponding to a
Thome, Néstor, Lebtahi Ep-Kadi-Hahifi, Leila, Catral, Minerva, Stuart, Jeffrey, Lebtahi, Leila, Catral, M.   +5 more
core   +1 more source

The R-mAtrIx Net

Machine Learning: Science and Technology
We provide a novel neural network architecture that can: i) output R-matrix for a given quantum integrable spin chain, ii) search for an integrable Hamiltonian and the corresponding R-matrix under assumptions of certain symmetries or other restrictions ...
Shailesh Lal, Suvajit Majumder, Evgeny Sobko   +2 more
doaj   +1 more source

Interfacing the B-Spline R-Matrix and R-Matrix with Time Dependence Computer Codes: An Update

Atoms
As a continuation of Schneider et al., Atoms 2022 10, 26, we report recent progress in the development and deployment of the interface between the computational codes B-Spline R-matrix (BSR) and R-Matrix with Time dependence (RMT).
Juan C. Del Valle, Aaron T. Bondy, Soumyajit Saha, Kathryn R. Hamilton, Klaus Bartschat   +4 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

spam: A Sparse Matrix R Package with Emphasis on MCMC Methods for Gaussian Markov Random Fields [PDF]

spam is an R package for sparse matrix algebra with emphasis on a Cholesky factorization of sparse positive definite matrices. The implemantation of spam is based on the competing philosophical maxims to be competitively fast compared to existing tools ...
Reinhard Furrer, Stephan R. Sain
core