Results 141 to 150 of about 1,105,597 (253)

Surgical Removal of Residual Tumor Masses in Patients Undergoing Targeted Therapy for EGFR‐Mutated Locally Advanced or Metastatic Lung Cancer

International Journal of Cancer, Volume 159, Issue 9, Page 2244-2261, 1 November 2026.
Non‐small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations often exhibit significant tumor reduction following tyrosine kinase inhibitor (TKI) therapy. Residual tumors frequently remain, however, leading to drug resistance and disease progression.
Fedor Moiseenko, Daniil Stroyakovskiy, Evgeniy Levchenko, Mikhail Fedyanin, Albina Gabina, Ani Oganesian, Sergey Belukhin, Maria Stepanova, Ekaterina Stepanova, Elizaveta Artemyeva, Alexander Myslik, Nikita Volkov, Alexei Bogdanov, Tatiana Shuginova, Kirill Kryukov, Valeria Kheinshtein, Arif Allakhverdiev, Ivan Zaberegniy, Yana Akhmadiyarova, Mikhail Popov, Anastasiya Danilova, Dmitriy Sehniaidze, Nikita Savelov, Nikita Levchenko, Evgeniy Slugin, Olga Lopushanskaya, Ekaterina Kuligina, Svetlana Aleksakhina, Aglaya Iyevleva, Alexandr Ivantsov, Vladimir Moiseyenko, Evgeny Imyanitov   +31 more
wiley   +1 more source

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10459-10474, November 2026.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch, Gargi Mishra, Magdalena Blaszkiewicz, Erica de Sousa, Jake W. Willows, Katharine W. Alltop, Annemarie Towle, Shawn Collins, Andre Khalil, Isabel F. Snodgrass, Lara Agha, Kiran Prakash, Rashmika Maganuru, Sugasini Dhavamani, John W. Newman, Kristy L. Townsend   +15 more
wiley   +1 more source

The Relevance of Curative‐Intent Metastasectomy in Colorectal Cancer Patients: Real‐World Insights From a Certified Comprehensive Cancer Center in Germany

International Journal of Cancer, Volume 159, Issue 8, Page 2025-2035, 15 October 2026.
Patients with metastatic colorectal cancer who are ineligible for upfront metastasectomy may still become candidates for secondary metastasectomy with curative intent following response to primary chemotherapy. However, most studies dichotomize metastatic colorectal cancer into resectable and unresectable disease.
Julian W. Holch, Jo‐Ann Eisenburger, Antony Weber, Iris Kammermeier‐Wehlau, Yannick Wiberg, Fabian Allmendinger, Kathrin Heinrich, Lena Weiss, C. Benedikt Westphalen, Victoria Krenmayr, Klara Dorman, Danmei Zhang, Theres Fey, Karin Berger‐Thürmel, Ulrich Wirth, Florian Kühn, Michael von Bergwelt‐Baildon, Jens Werner, Volker Heinemann   +18 more
wiley   +1 more source

Five‐Year Survival Analyses on Non‐Pathological Complete Response Esophageal Squamous Cell Carcinoma Patients After Neoadjuvant Regimens Plus Surgery: A Propensity Score Matching, Real‐World Cohort Study

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Non‐pathological complete response (non‐pCR) is common in esophageal squamous cell carcinoma (ESCC) patients after neoadjuvant therapy, yet evidence guiding long‐term outcomes and postoperative risk stratification in the immunotherapy era remains limited.
Weibin Liu, Yujie Deng, Yan Lin, Yijin Lin, Xuejin Zheng, Weikun Su, Weijin Xiao, Yi Shi, Jiarong Zhang, Xiaohui Chen   +9 more
wiley   +1 more source

Head & Neck and Shoulder Desmoid‐Type Fibromatosis: Presentation and Natural History of These Ultra‐Rare Locations

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Active surveillance is recommended as the first‐line management for desmoid‐type fibromatosis (DF); however, data on DF of the head and neck (H&N) and shoulder regions are limited. Methods We examined patients with DF located in the H&N and shoulder regions, comparing baseline characteristics and event‐free survival (EFS).
Nicolas Penel, Sylvie Bonvalot, Julien Elices‐Diez, Antoine Italiano, Benjamin Verret, Jean‐Emmanuel Kurtz, Pascale Dubray‐Longeras, Cécile Guillemet, Florence Duffaud, François Bertucci, Julien Thery, Marie Vanseymortier, Emmanuelle Bompas, Nelly Firmin, Sixtine De Percin, Jennifer Wallet, Sophie Piperno‐Neumann, Thibaud Valentin, Jean‐Yves Blay, Marie‐Cécile Le Deley   +19 more
wiley   +1 more source

Preoperative Arterial Embolization Facilitating Safe Resection of a Hypervascular Aggressive Angiomyxoma: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 22‐year‐old woman presented with a 12‐cm hypervascular aggressive angiomyxoma. Difficult hemostasis during biopsy prompted preoperative selective arterial embolization followed by complete macroscopic resection with only 50 mL of blood loss.
Yukako Takashima, Shinichi Terada, Yoshimichi Tanaka, Takashi Yamada, Kazuhiro Yamamoto, Yoshinobu Hirose, Tomohito Tanaka   +6 more
wiley   +1 more source

Optimising Clinical Outcomes Following R1 Resection in Soft Tissue Sarcoma: An Evidence-Based Approach. [PDF]

Curr Treat Options Oncol
Remiszewski P, Rosiński M, Sukiennik AS, Chmiel P, Szumera-Ciećkiewicz A, Rutkowski P, Czarnecka AM.   +6 more
europepmc   +1 more source

Pattern‐Based P53 Immunohistochemistry Predicts Recurrence in Colorectal Liver Metastases Without Complete Pathologic Response After Neoadjuvant Chemotherapy

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Aberrant p53 expression may have prognostic significance in colorectal cancer; however, its role in patients with colorectal liver metastases (CRLM) who receive neoadjuvant chemotherapy but do not achieve pathological complete response (pCR) remains unclear.
Phat Thi Hong Ho, Duy Duc Nguyen, Vuong Dinh Thy Hao, Giang Huong Tran, Lam Viet Trung, Thinh Van Hoang, Hoang Bac Nguyen   +6 more
wiley   +1 more source

Intraoperative indeterminate frozen-section margin leading to an unintended R1 resection in perihilar cholangiocarcinoma: a case report and decision-making framework. [PDF]

Front Surg
Li X, Wang J, Liu L, Wei Y, Wang Y, Sun J.   +5 more
europepmc   +1 more source

Redefining the R1 resection in patients with pancreatic ductal adenocarcinoma

Journal of hepato-biliary-pancreatic sciences, 2016
P. Markov, S. Satoi, M. Kon
semanticscholar   +1 more source