Results 131 to 140 of about 1,105,597 (253)

Is R1 vascular hepatectomy for hepatocellular carcinoma oncologically adequate? Analysis of 327 consecutive patients

open access: yes, 2019
Background: R1 vascular resection for liver tumors was introduced in the early twenty-first century. However, its oncologic adequacy remains controversial.
Vigano' L   +8 more
core   +1 more source

Evaluation of Additional Treatment for Residual Cases After Endoscopic Papillectomy of Duodenal Ampullary Tumors

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aims This study aimed to assess the prognosis and outcomes of additional treatment for residual adenocarcinoma and adenoma following endoscopic papillectomy (EP) for ampullary tumors. Methods Of 191 patients who underwent EP, 43 with adenocarcinoma or adenoma and either positive or unknown pathological margins were included ...
Yusuke Kurita   +24 more
wiley   +1 more source

The role of biofeedback in improving anal continence after anterior resection

open access: yes, 2010
Incorporation of routine biofeedback into the management of patients with rectal cancer who are undergoing anterior resection offers potential for improved anal continence compared with standard management.
Pilkington, Sophie A.
core   +1 more source

Nontumor‐Specific mRNA Sensitization of Cold Tumors to Immune Checkpoint Blockade: Evidence, Bias, and Requirements for Translation

open access: yesAdvanced Oncology, Volume 1, Issue 1, December 2026.
Messenger RNA constructs encoding nontumor antigens are proposed to sensitize cold tumors to checkpoint blockade. Observational survival estimates favor vaccination but are heterogeneous, and bias‐focused analyses find no significant difference once time‐zero is aligned. Epitope spreading remains undemonstrated in humans. This review separates what the
Sarfaraz K. Niazi
wiley   +1 more source

Adjuvant Chemotherapy Regimens in Resected Biliary Tract Cancers: National, Comparative, Observational Study (TOG/GI‐SAFRADJU‐2501)

open access: yesInternational Journal of Cancer, Volume 159, Issue 11, Page 2766-2777, 1 December 2026.
ABSTRACT The recommended adjuvant chemotherapy (adj‐ChT) regimen for resected biliary tract cancers (BTC) is capecitabine (Cape); yet, the recommendation is based on limited evidence. Although varied adj‐ChTs have been employed in practice, robust real‐world data is scarce. We conducted a national, multicenter, hospital‐based registry study to evaluate
Erman Akkus   +60 more
wiley   +1 more source

Association Between Socioeconomic Position and Diagnosis, Treatment and Survival of Patients With Stage I–III Rectal Cancer in the Netherlands

open access: yesInternational Journal of Cancer, Volume 159, Issue 11, Page 2665-2675, 1 December 2026.
ABSTRACT Socioeconomic position (SEP) influences cancer care and outcomes, even in countries with government‐funded healthcare. This population‐based study examined associations between SEP, rectal cancer care and survival of patients in the Netherlands.
Suzanne E. N. de Vries   +10 more
wiley   +1 more source

Impact of RAS/RAF Mutations on Metastatic Treatment Response Following Total Neoadjuvant Therapy in Patients With Stage IV Rectal Cancer

open access: yesAsia-Pacific Journal of Clinical Oncology, Volume 22, Issue 6, Page 817-829, December 2026.
There is limited understanding of the impact of underlying RAS/RAF mutational status on total neoadjuvant therapy metastatic tumor response rates in curative Stage IV rectal cancer patients. Complete metastatic tumor response to TNT was demonstrated in half as many mRAS as wtRAS patients and disease progression was higher in patients harboring RAS ...
Tracy R. Fitzsimmons   +8 more
wiley   +1 more source

Tumor invasion loci in resected margins of perihilar cholangiocarcinoma and their impact on survival: a retrospective 13-year longitudinal cohort study

open access: yesWorld Journal of Surgical Oncology
Background Perihilar cholangiocarcinoma (PHC) presents significant challenges in achieving curative resection, with current definitions of radicality (R0/R1/R2) based solely on tumor presence at margins lacking prognostic precision.
Yury Kovalenko   +9 more
doaj   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

open access: yesPediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier   +18 more
wiley   +1 more source

The impact of margins and re‐resection in pediatric synovial sarcoma

open access: yesCancer Medicine
Introduction Synovial sarcoma is one of the most common soft tissue sarcomas in children. Guidelines regarding the adequate extent of resection margins and the role of re‐resection are lacking.
Andres F. Espinoza   +12 more
doaj   +1 more source

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