Results 121 to 130 of about 1,105,597 (253)

Perioperative Durvalumab for Resectable NSCLC: Updated Outcomes for Japanese Patients in AEGEAN

Cancer Science, EarlyView.
In prespecified exploratory analyses of Japanese patients with resectable NSCLC enrolled in the AEGEAN trial, perioperative durvalumab plus neoadjuvant chemotherapy demonstrated clinically meaningful improvements in the primary endpoints of EFS and pCR versus neoadjuvant chemotherapy alone.
Tetsuya Mitsudomi, John V. Heymach, Yoshitsugu Horio, Fumihiro Tanaka, Hiroshi Tanaka, Shoichi Kuyama, Morihito Okada, Shinichi Toyooka, Yasutaka Watanabe, Martin Reck, David Harpole, Janis M. Taube, Yuka Olivo, Huiling Xiong, Tamer M. Fouad, Allen Chen, Hiroaki Akamatsu   +16 more
wiley   +1 more source

Assessment of MRD and Longitudinal Monitoring of Post‐Surgery Biliary Tract Cancer With a Customized ctDNA Panel

Cancer Science, EarlyView.
A customized panel was established for BTC MRD detection. Preoperative ctDNA detection was associated with pathological stage and poorer RFS and OS. Longitudinal monitoring detected ctDNA before radiological recurrence in 72.7% of patients, with a median lead time of 77 days, supporting ctDNA as a complementary prognostic biomarker with CA19‐9 ...
Yoshihito Shinohara, Toru Nakamura, Yasutoshi Kimura, Takeshi Murakami, Shigeyuki Kojima, Toshikazu Yamaguchi, Kanako C. Hatanaka, Ryo Okazaki, Yosuke Kitayama, Keita Fukuda, Fabio Pittella‐Silva, Yusuke Nakamura, Satoshi Hirano, Siew‐Kee Low   +13 more
wiley   +1 more source

Risk factors and prognosis of postoperative early relapse after neoadjuvant therapy for locally advanced esophageal squamous cell carcinoma: a retrospective study

World Journal of Surgical Oncology
Background This study aimed to identify risk factors associated with early postoperative relapse and evaluate their impact on survival outcomes after neoadjuvant therapy for locally advanced esophageal squamous cell carcinoma (LA-ESCC), thereby informing
Ze-Gang Chen, Yue-Yun Chen, Zhen Lin, Pan-Pan Lin, Qing Li, Yu-Shang Yang, Hua-Shan Shi, Zhen-Yu Ding   +7 more
doaj   +1 more source

Outcome of Endoscopic Resection of Rectal Neuroendocrine Tumors ≤ 10 mm

Diagnostics
Background and aim: Guidelines suggest endoscopic resection for rectal neuroendocrine tumors (rNETs) < 10 mm, but the most appropriate resection technique is unclear.
Roberta Elisa Rossi, Maria Terrin, Silvia Carrara, Roberta Maselli, Alexia Francesca Bertuzzi, Silvia Uccella, Andrea Gerardo Antonio Lania, Alessandro Zerbi, Cesare Hassan, Alessandro Repici   +9 more
doaj   +1 more source

Update of the S1‐guideline atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS)

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) are rare cutaneous neoplasms representing histomorphological, genetic as well as epigenetic variants of one disease spectrum. Both tumors manifest as nonspecific, often ulcerated nodules in chronically sun‐damaged skin. AFX is a well‐demarcated, often rapidly growing tumor.
Doris Helbig, Mirjana Ziemer, Diana Crisan, Edgar Dippel, Michael Erdmann, Uwe Hillen, Muemtaz Koeksal, Ulrike Leiter, Thomas Mentzel, Lars Erik Podleska, Jochen Utikal, Dagmar von Bubnoff, Carsten Weishaupt, Selma Ugurel   +13 more
wiley   +1 more source

Stroma AReactive Invasion Front Areas (SARIFA) is a negative prognostic factor for overall survival in non‐intestinal gastric adenocarcinomas

Histopathology, EarlyView.
SARIFA – characterized by direct tumour cell‐adipocyte contact – is a novel histological marker that is easily identifiable on standard haematoxylin–eosin‐stained sections and is associated with aggressive tumour behaviour. SARIFA positivity independently predicts poorer survival outcomes in non‐intestinal gastric cancer and may thus contribute to ...
Ákos Jakab, Luca Szalai, Bettina Zengő, Ildikó Kocsmár, Tibor Várkonyi, István Kenessey, Attila Szijártó, András Kiss, Tamás Vass, Gábor Lotz, Éva Kocsmár   +10 more
wiley   +1 more source

R1-subtype foot domain glycerol binding site is not present in R2-subtype tail fiber NTF.

, 2019
Glycerol binding pocket with all residues within 6 Å of the ligand highlighted. (left) R1-NTF surface coulombic map with glycerol ligand (black, colored by element); (right) Surface coulombic map of analogous aligned region in the R2-NTF foot. Comparison
Adam J. Salazar (6298307), Jennifer Tsai (1204), James C. Sacchettini (37661), Mukul Sherekar (6298310)   +3 more
core   +1 more source

Assessing the ability of large language models to summarize and generate maxillofacial prosthetic treatment options

Journal of Prosthodontics, EarlyView.
Abstract Purpose The aim was to evaluate the ability of four large language models (LLMs) (OpenAI's ChatGPT‐3.5, Microsoft 365 Copilot, DeepSeek‐R1, and Google Gemini 2.5 Pro) to develop treatment options when presented with clinical cases published in the maxillofacial prosthodontics literature.
Leila M. Sears, Merve Koseoglu, Stavroula Antonopoulou, Sarah Kay Youny Lee, Michael Kase, Amanda Colebeck, Yu‐Chun (Jessie) Lin, Heidi Huber, Maribeth Krzesinski, Alvin G. Wee, Cortino Sukotjo   +10 more
wiley   +1 more source

Factors that may contribute to non-radical resections in patients undergoing breast-conserving treatment for breast cancer

Nowotwory
INTRODUCTION: Breast-conserving treatment in breast cancer consists of radical removal of the cancerous tumor combi­ned with a satisfactory aesthetic result.
Andrzej J. Lorek, Katarzyna Steinhof-Radwańska, Wojciech Zarębski, Joanna Lorek, Zoran Stojcev   +4 more
doaj   +1 more source

Temporary caval occlusion technique during right divisional hepatectomy for massive hepatocellular carcinoma with caudal vena cava compression/involvement in dogs

Veterinary Surgery, EarlyView.
Abstract Objective To describe the perioperative and long‐term outcomes of dogs with massive hepatocellular carcinoma (HCC) in the right hepatic division causing compression or involvement of the caudal vena cava (CVC) treated with right divisional hepatectomy using temporary caval occlusion (TCO). Study design Retrospective case series.
Kumiko Ishigaki, Kazushi Asano, Kei Tamura, Tatsuya Heishima, Takeshi Hayakawa, Teppei Fujimoto, Kenji Teshima   +6 more
wiley   +1 more source