Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers [PDF]
Dimerization of the thrombopoietin receptor (TpoR) is necessary for receptor activation and downstream signaling through activated Janus kinase 2. We have shown previously that different orientations of the transmembrane (TM) helices within a receptor ...
Balligand, Thomas +12 more
core +2 more sources
Renewable and waste heat applications for heating, cooling, and power generation based on advanced configurations [PDF]
Using renewable heat energy sources, recovering the waste heat, and enhancing the processes and energy efficiency can reduce the electricity dependency of several industrial applications.
Al-Sayyab, Ali +2 more
core +1 more source
STUDIO SPERIMENTALE E NUMERICO DELLA CONDENSAZIONE DI R513A E R516A IN CANALI DI PICCOLO DIAMETRO
Considerando il sempre maggiore impiego della refrigerazione e delle pompe di calore sia nel settore civile che in quello industriale, risulta fondamentale la ricerca di fluidi refrigeranti a basso impatto ambientale, tenendo presenti le restrizioni provenienti dalle autorità.
openaire +2 more sources
Symbionte - Desarrollo de un dispositivo IOT enfocado en la protección y monitorización de compresores en aplicaciones de aire acondicionado y refrigeración [PDF]
ilustraciones, fotografías a colorThis project addresses the problem of the correct diagnosis of air conditioning and refrigeration systems compressors, using instrumentation easily found in the market.
Sierra Sierra, Nelson Ariel
core +1 more source
Thermodynamic Analysis for the Selection of low GWP Refrigerants in Ground Source Heat Pumps [PDF]
One of the main objectives of the European Commission in the buildings sector, responsible for approximately 40% of total energy consumption and 36% of greenhouse gas emissions, is to identify technological solutions capable of reducing energy ...
Bernardi, Adriana +10 more
core +1 more source
This study analyzes four alternative cycle configurations for the traditional vapor compression system used in conventional, hybrid, and electric vehicles, taking low-GWP alternatives for the substitution of R134a.
D. Méndez-Méndez +4 more
doaj +1 more source
Eph Receptor Clustering by Chondroitin Sulfate Inhibits Axon Regeneration [PDF]
Chondroitin sulfate proteoglycans (CSPGs) play important roles in the developing and mature nervous system, where they guide axons, maintain stable connections, restrict synaptic plasticity, and prevent axon regeneration following CNS injury.
Miller, Gregory Martin
core +1 more source
Duality of gauge field singularities and the structure of the flux tube in Abelian-projected SU(2) gauge theory and the dual Abelian Higgs model [PDF]
金沢大学総合メディア基盤センター The structure of the flux-tube profile in Abelian-projected (AP) SU(2) gauge theory in the maximally Abelian gauge is studied. The connection between the AP flux tube and the classical flux-tube solution of the U(1) dual Abelian Higgs ...
Ilgenfritz Ernst Michael +4 more
core +3 more sources
Machine and deep learning driven models for the design of heat exchangers with micro-finned tubes [PDF]
The design of micro-finned tube heat exchangers is a complex task due to intricate geometry, heat transfer goals, material selection, and manufacturing challenges. Nowadays, mathematical models provide valuable insights, aid in optimization, and allow us
Diani A. +3 more
core +4 more sources

