Results 41 to 50 of about 12,715 (182)

Identification of tiger and lion skulls: An illustrated guide for science and practice

Zoologica Scripta, Volume 54, Issue 3, Page 291-304, May 2025.
Abstract Tiger and lion bones are valuable subjects of trafficking. They can be easily interchanged. The aim of this study was to develop a methodology to quickly distinguish between tiger and lion skulls. From a number of features reported in the literature, a set of seven significant characters was identified that can be recognized even in ...
Dominika Formanova, Anna Kubatova
wiley   +1 more source

Exploration of Aromatic Hydrazides as Inhibitors of Human Carbonic Anhydrases

Archiv der Pharmazie, Volume 358, Issue 4, April 2025.
Hydrazide‐based derivatives were evaluated as inhibitors of human carbonic anhydrase (hCA) isoforms I, II, IV, IX, and XII. Several derivatives, particularly those with ureido‐linkers, exhibited strong inhibitory activity with inhibition constants in the low micromolar range.
German Benito Menendez, Simone Giovannuzzi, Alessandro Bonardi, Alessio Nocentini, Paola Gratteri, Claudiu T. Supuran   +5 more
wiley   +1 more source

Property Valuation and Taxation for Fiscal Sustainability – Lessons for Poland

Real Estate Management and Valuation, 2019
Research undertaken by the World Bank in Europe and the Central Asia Region indicates that there are four principal preconditions for introducing value-based recurrent property tax reforms: comprehensive property registration, a reliable source of data ...
Grover Richard, Walacik Marek
doaj   +1 more source

An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer [PDF]

, 2017
KRAS mutated tumours represent a large fraction of human cancers, but the vast majority remains refractory to current clinical therapies. Thus, a deeper understanding of the molecular mechanisms triggered by KRAS oncogene may yield alternative ...
Andersen, Jesper B., Arricibita, Andrea, Bailey, Peter, Biankin, Andrew, Bozec, Aline, Chang, David K., Chuang, Chen-Hua, Guembe, Laura, Guruceaga, Elisabet, Gwinn, Dana, Khatri, Purvesh, Lecanda, Fernando, Martinez-Canarias, Susana, Mazur, Pawel K., Perurena, Naiara, Ponz-Sarvise, Mariano, Sage, Julien, Sayles, Leanne C., Sweet-Cordero, E. Alejandro, Valencia, Karmele, Vallejo, Adrian, Vicent, Silve, Zandueta, Carolina   +22 more
core   +3 more sources

Pharmacological Dissection Identifies Retatrutide Overcomes the Therapeutic Barrier of Obese TNBC Treatments through Suppressing the Interplay between Glycosylation and Ubiquitylation of YAP

Advanced Science, Volume 12, Issue 11, March 20, 2025.
This study reveals that obesity‐driven metabolic dysfunction enhances YAP O‐GlcNAcylation, facilitating its stabilization by preventing ubiquitylation and degradation via EIF3H, thereby driving TNBC progression and chemoresistance. Retatrutide disrupts this axis by suppressing O‐GlcNAcylation, restoring YAP ubiquitylation, and enhancing degradation ...
Xin Cui, Yueming Zhu, Lidan Zeng, Mengyuan Zhang, Amad Uddin, Theresa W. Gillespie, Lauren E. McCullough, Shaying Zhao, Mylin A. Torres, Yong Wan   +9 more
wiley   +1 more source

Conditions of Local Development in the Context of Shaping Developmental Strategy and Policy in Poland

Studia Ekonomiczne i Regionalne, 2020
Subject and purpose of work: This paper discusses the essence and main areas of conditions of local development in the context of the political transformations which have occurred in Poland over the last thirty years.
Adamowicz Mieczysław
doaj   +1 more source

An Insect Effector Mimics Its Host Immune Regulator to Undermine Plant Immunity

Advanced Science, Volume 12, Issue 11, March 20, 2025.
Under normal conditions, high OsGF14e expression recruits OsEDR1l and enhances OsEDR1l‐mediated MAPK cascade to restrict immunity and promote plant growth. Upon insect infestation, the OsGF14e signaling circuit is rewired toward active immune responses that confer resistance to BPH at the expense of growth.
Jianmei Fu, Shuai Li, jing Li, Zhichang Zhao, Jing Li, Xinyang Tan, Shan Yu, Maofeng Jing, Keyan Zhu‐Salzman, Jichao Fang, Rui Ji   +10 more
wiley   +1 more source

Development of Areas and Public Purpose Investments in Suburban Territories

Real Estate Management and Valuation, 2014
Suburban areas are subjected to particularly strong investment pressure, thus facing the challenge arising from the need to impose new spatial order. Satisfying the residents’ expectations by implementing necessary technical and social infrastructure ...
Wolny Ada, Źróbek-Rózańska Alina, Źróbek Ryszard, Piotrowski Marek, Frey Jens   +4 more
doaj   +1 more source

Zooming into firms’ location, capabilities and innovation performance: Does agglomeration foster incremental or radical innovation?

European Research on Management and Business Economics, 2022
This study answers the question on whether areas of agglomeration or high industry specialization constitute supportive prone-to-innovation environments for the generation of radical innovation.
Jose-Luis Hervas-Oliver, Francisca Sempere-Ripoll, Carles Boronat Moll   +2 more
doaj   +1 more source

Sphere packing bounds via spherical codes [PDF]

, 2013
The sphere packing problem asks for the greatest density of a packing of congruent balls in Euclidean space. The current best upper bound in all sufficiently high dimensions is due to Kabatiansky and Levenshtein in 1978.
Cohn, Henry, Zhao, Yufei
core   +1 more source