Results 201 to 210 of about 162,658 (282)

Mechanistic Insights and Pharmacological Approaches for Nitrogen and Sulfur Mustards and Their Implications as Therapeutic Agents

Journal of Applied Toxicology, Volume 45, Issue 8, Page 1417-1425, August 2025.
ABSTRACT Nitrogen and sulfur mustards, often acting as vesicants, have significant consequences for public health. Skin is a common site for exposure to these vesicants that can result in considerable morbidity and mortality. Given that the treatment options are limited, new insights into the mechanisms for the toxicity of these vesicants that can be ...
Madison Owens, Anita Thyagarajan, Jeffrey B. Travers, Ravi P. Sahu   +3 more
wiley   +1 more source

Viral replication site distribution for rabbit hemorrhagic disease virus 2 in formalin-fixed, paraffin-embedded tissues via in situ hybridization. [PDF]

J Vet Diagn Invest, 2022
O'Toole AD, Zhang J, Williams LBA, Brown CC.   +3 more
europepmc   +1 more source

Preliminary Study on The SYBR Green I RT- qPCR for Rabbit Hemorrhagic Disease Virus 2 (RHDV2) Detection [PDF]

, 2017
Zexiao Yang, Yadong Liu, Zhengqun MENG, Bo Wang, Xueping Yao, Yin Wang, Yi Geng, Yan Li   +7 more
openalex   +1 more source

Role of NRP1/HDAC4/CREB/RIPK1 Axis in SARS‐CoV2 S1 Spike Subunit‐Induced Neuronal Toxicity

FASEB BioAdvances, Volume 7, Issue 8, August 2025.
Extracellular SARS‐CoV2 Spike‐S1 protein via NRP1 internalizes in the cytosol of SH‐SY5Y cells. Once inside, it upregulates the epigenetic eraser HDAC4, which binds transcriptional factor CREB, causes RIPK1 up‐regulation, and therefore necroptotic cell death.
Luca Sanguigno, Natascia Guida, Mariarosaria Cammarota, Silvia Ruggiero, Angelo Serani, Francesca Galasso, Vincenzo Pizzorusso, Francesca Boscia, Luigi Formisano   +8 more
wiley   +1 more source

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

European Journal of Clinical Investigation, Volume 55, Issue 8, August 2025.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina, Fábio França Vieira e Silva, Rafael Antônio Velôso Caixeta, Bruna de Oliveira Rech, Alba Perez‐Jardón, María Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Paulo Henrique Braz‐Silva, Karem L. Ortega   +8 more
wiley   +1 more source

Kindlin‐2 Deletion in Mural Cells Leads to Vascular Instability

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
Kindlin‐2 in vSMCs and pericytes facilitates activation of β1‐ and β3‐integrin receptors and thereby promotes integrin‐mediated adhesion, contractile phenotype, and survival, which are crucial to their coverage of blood vessels and vascular stabilization.
Katarzyna Bialkowska, Dorota Szpak, Dmitriy Verbovetskiy, Jun Qin, Olga A. Cherepanova, Edward F. Plow, Elzbieta Pluskota   +6 more
wiley   +1 more source

Epitope Insertion at the N-Terminal Molecular Switch of the Rabbit Hemorrhagic Disease Virus T=3 Capsid Protein Leads to Larger T=4 Capsids

, 2012
Daniel Luque, José M. González, Josué Gómez-Blanco, R. Marabini, Javier Chichón, Ignacio Mena, Ivan L. Ângulo, José L. Carrascosa, Núria Verdaguer, Benes L. Trus, Juan Bárcena, José R. Castón   +11 more
openalex   +1 more source

Rabbit Hemorrhagic Disease Virus in Mexico in 2020-2021: Risk Areas and Climatic Distribution. [PDF]

Viruses
Lorenzo C, Fernández JA, Hernández-Quiroz NS, Lafón Terrazas A, Tapia-Ramírez G.   +4 more
europepmc   +1 more source

Detection of rabbit hemorrhagic disease virus 2 in formalin-fixed, paraffin-embedded tissues via in situ hybridization. [PDF]

J Vet Diagn Invest, 2022
O'Toole AD, Zhang J, Williams LBA, Brown CC.   +3 more
europepmc   +1 more source

Nucleolin interacts with the rabbit hemorrhagic disease virus replicase RdRp, nonstructural proteins p16 and p23, playing a role in virus replication. [PDF]

Virol Sin, 2022
Zhu J, Miao Q, Guo H, Tang A, Dong D, Tang J, Wang F, Tong G, Liu G.   +8 more
europepmc   +1 more source