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A recombinant canarypox virus protects rabbits against a lethal rabbit hemorrhagic disease virus (RHDV) challenge

Vaccine, 1997
An ALVAC (canarypox)-based recombinant virus ALVAC-RHDV (vCP309) expressing a native rabbit hemorrhagic disease virus (RHDV) capsid protein was derived and assessed for its protective efficacy in rabbits. Protection against a lethal RHDV challenge was demonstrated in rabbits inoculated twice with either high (10(7) p.f.u.) or low (10(5) p.f.u.) doses ...
L, Fischer   +3 more
openaire   +2 more sources

Sequence and genomic organization of a rabbit hemorrhagic disease virus isolated from a wild rabbit

Virus Genes, 1995
Rabbit hemorrhagic disease virus (RHDV) is a member of the caliciviridae family. The nucleotidic sequence of a full-length cDNA of one RHDV isolate (RHDV-SD) is reported. The genome is 7437 bases long and includes two ORFs, ORF1 (7034 b) and ORF2 (353 b), coding for the polyprotein and the Vp12, respectively.
Rasschaert, Denis   +3 more
openaire   +3 more sources

Clinicopathologic findings of naturally occurring Rabbit Hemorrhagic Disease Virus 2 infection in pet rabbits

Veterinary Clinical Pathology, 2019
AbstractTwo pet rabbits were presented with an acute decrease in appetite and activity. Rabbit 1 showed severe hypothermia, bradycardia, arrhythmias, a heart murmur, dyspnea, occlusion of the nares with secretions, icterus, dehydration, and gaseous gastrointestinal dilation. The urine was dark yellow. Rabbit 2 was overweight, apathetic, and dehydrated;
Cristina, Bonvehí   +7 more
openaire   +2 more sources

Rabbit hemorrhagic disease virus poly(A) tail is not essential for the infectivity of the virus and can be restored in vivo

Archives of Virology, 2008
The precise role of the poly(A) tail at the 3'-end of the calicivirus RNA genome is unknown. To study the relationship between the presence of the poly(A) tail and the infectivity and replication of rabbit hemorrhagic disease virus (RHDV), mutants of an infectious cDNA clone of RHDV were constructed, and RK13 cells were transfected with transcripts ...
G-Q, Liu   +6 more
openaire   +2 more sources

Rabbit hemorrhagic disease virus—molecular cloning and nucleotide sequencing of a calicivirus genome

Virology, 1991
The RNA genome of rabbit hemorrhagic disease virus (RHDV) was molecularly cloned. The 5' terminal sequence of the genomic RNA was determined after PCR amplification of a G-tailed first strand cDNA template. The cloned cDNA allowed determination of the first complete caliciviral sequence encompassing 7437 nucleotides without poly(A) tail.
G, Meyers, C, Wirblich, H J, Thiel
openaire   +2 more sources

European brown hare syndrome virus: relationship to rabbit hemorrhagic disease virus and other caliciviruses

Journal of Virology, 1994
Monoclonal antibodies directed against the capsid protein of rabbit hemorrhagic disease virus (RHDV) were used to identify field cases of European brown hare syndrome (EBHS) and to distinguish between RHDV and the virus responsible for EBHS. Western blot (immunoblot) analysis of liver extract of an EBHS virus (EBHSV)-infected hare revealed a single ...
C, Wirblich   +6 more
openaire   +2 more sources

Emergence of new virulent rabbit hemorrhagic disease virus strains in Saudi Arabia

Tropical Animal Health and Production, 2016
Rabbit hemorrhagic disease is an acute fatal highly contagious viral infectious disease that causes high losses among rabbitries. The disease was first reported in China in 1984 and later on in Saudi Arabia in 1996. The aim of this study was to investigate the emergence and pathogenicity of new rabbit hemorrhagic disease virus (RHDV) strains in Saudi ...
Mahmoud M, Ismail   +3 more
openaire   +2 more sources

[A new virus of rabbit. III. Study on morphological superstructure and antigenicity of rabbit hemorrhagic disease virus (RHDV)].

Wei sheng wu xue bao = Acta microbiologica Sinica, 1993
In the spring 1986, an acute infectious disease occurred in Wuhan Second Producing Medical Manufactory, and the rabbit almost died. We tested the mortal symptom and confirmed rabbit Hemorrhagic Disease (RHD) as same as Huang Yinyao report. Hubei Traditional Chinese Medicine Institute appear this RHD also.
L, Zhao, T, Li, B, Song, F, Sun
openaire   +1 more source

Multiple Introductions of Rabbit Hemorrhagic Disease Virus Lagovirus europaeus/GI.2 in Africa

Biology, 2021
Faten Ben Chehida   +2 more
exaly  

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