Results 71 to 80 of about 1,478 (205)

FORMULATION AND EVALUATION OF RACECADOTRIL MUCOADHESIVE MICROSPHERES

International Journal of Pharmacy and Pharmaceutical Sciences, 2019
Objective: To develop and evaluate the mucoadhesive microsphere using combinations of natural polymers chitosan and xanthan gum for sustained release. Methods: In the present work mucoadhesive microspheres were prepared by using natural polymers like chitosan and xanthan gum by using the emulsion chemical cross-linking method.
KANCHAN JAMKAR, SWATI MUTHA, SHARWAREE HARDIKAR, NIKHIL KUMBHAR   +3 more
openaire   +2 more sources

Hereditary angioedema in children: Review and practical perspective for clinical management

Pediatric Allergy and Immunology, Volume 35, Issue 12, December 2024.
Abstract Background Hereditary angioedema (HAE) in children has specific features and requires multidisciplinary management. Methods We performed a literature search and underwent in‐depth discussions to provide practical tools for physicians. Results HAE is a rare, life‐threatening genetic disorder.
Anne Pagnier, Angelina Dermesropian, Charlotte Kevorkian‐Verguet, Mélisande Bourgoin‐Heck, Cyrille Hoarau, Héloïse Reumaux, Frédérique Nugues, Christine Audouin‐Pajot, Sibylle Blanc, Aurélia Carbasse, Anne‐Laure Jurquet, Mélanie Voidey, Mona Villedieu, Laurence Bouillet, Isabelle Boccon‐Gibod   +14 more
wiley   +1 more source

Analysis of factors influencing the overall effect of racecadotril on childhood acute diarrhea. Results from a real-world and post-authorization surveillance study in Venezuela

Therapeutics and Clinical Risk Management, 2010
Jose ChacónOn behalf of the Racecadotril Post-authorization Record Group; Centro Clinico Profesional Caracas, Caracas, VenezuelaAbstract: Drug efficacy might differ from clinical trial results when performed in clinical daily conditions ...
Jose Chacón
doaj  

Role of Antidiarrhoeal Drugs as Adjunctive Therapies for Acute Diarrhoea in Children

International Journal of Pediatrics, 2013
Acute diarrhoea is a leading cause of child mortality in developing countries. Principal pathogens include Escherichia coli, rotaviruses, and noroviruses. 90% of diarrhoeal deaths are attributable to inadequate sanitation.
Christophe Faure
doaj   +1 more source

Use (or Misuse) of Drugs in Pediatrics [PDF]

, 2011
Introdução e Objectivos: A exposição a fármacos na idade pediátrica pode ser nociva. A utilização elevada de medicamentos não aprovados em Pediatria, bem como o uso para sintomas em que a sua eficácia não foi comprovada, tem sido descrita de forma ...
Almeida, H, Brito, MJ, Luís, C, Maia, R, Moura, M, Ribeiro, R   +5 more
core  

Patch tests in non‐immediate cutaneous adverse drug reactions: Late readings on Day 4 is more sensitive than on Day 3

Contact Dermatitis, Volume 91, Issue 4, Page 321-326, October 2024.
Our study shows that a second reading at D4 (24.9%) enchances the sensitivity of a first reading at D3 (13.7%) for the patients' positivity of PTs with suspect drugs in the exploration of NICADR (p < 0.0001). Late readings should not be carried out on D3 because of an important loss of sensibility compared to D4.
Ilaria Matei, Thomas Bettuzzi, Amandine Weill, Gwendeline Gener, Kamar Bel Hareth, Fleck Margaux, Muriel Verlinde‐Carvalho, Muriel Paul, Saskia Ingen‐Housz‐Oro, Haudrey Assier   +9 more
wiley   +1 more source

Long term outcomes in children with trichohepatoenteric syndrome

American Journal of Medical Genetics Part A, Volume 194, Issue 2, Page 141-149, February 2024.
Abstract Trichohepatoenteric syndrome (THES) is a rare autosomal recessive disorder caused by mutations in either TTC37 or SKIV2L, usually leading to congenital diarrhea as part of a multisystem disease. Here, we report on the natural history of the disease for the largest UK cohort of patients with THES from 1996 to 2020.
Kwang Yang Lee, Ronald Bremner, Jane Hartley, Sue Protheroe, Wolfram Haller, Tracey Johnson, Lisa Whyte   +6 more
wiley   +1 more source

Determination of racecadotril by HPLC in capsules

Indian Journal of Pharmaceutical Sciences, 2007
A simple, precise and rapid RP-HPLC method was developed for the determination of racecadotril in a pharmaceutical formulation using gemfibrozil as internal standard. Ratio of the peak area of analyte to internal standard was used for quantification. The chromatographic separation was carried out by using a Reverse Phase C18 column (BDS-Hypersil).
A Shirwaikar, SL Prabu, T Singh, A Joseph, CDinesh Kumar   +4 more
openaire   +1 more source

Protein Kinase Inhibitors Indicated for Lung Cancer: Pharmacodynamics, Pharmacokinetics, Adverse Drug Reactions, and Evaluation in Clinical Trials

Journal of Clinical Pharmacy and Therapeutics, Volume 2024, Issue 1, 2024.
WhatIs Known and Objective. Anti‐EGFR (epidermal growth factor receptor) drugs are indicated for non‐small‐cell lung cancer (NSCLC). This review summarises the information available to date on the first anti‐EGFRs granted market authorisation: erlotinib TARCEVA®, gefitinib IRESSA®, afatinib GIOTRIF®, dacomitinib VIZIMPRO®, and osimertinib TAGRISSO ...
Constance Bordet, Vincent Dongay, Yoann Zelmat, Julien Mazieres, Fabien Despas, Samuel Silvestre   +5 more
wiley   +1 more source

Evaluasi Penggunaan Obat pada Pasien Balita Terkena Diare pada Pasien Rawat Inap RSUD Kota Surakarta Tahun 2014 [PDF]

, 2016
Diarrhea is a disease which marked by increasing frequency of defecation more than three times in a day that accompanied by liquid stools with or without blood or mucus. According to Word Gastroenterology organisation (2012), management of children with
, Zakky Cholisoh, M.Clin.Pharm., Ph.D., Apt, Septiani, Sundari   +1 more
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