Results 51 to 60 of about 701 (178)

Multivariate Optimization of Chromatographic Conditions for Rapid Simultaneous Quantification of Antidiarrheal Drugs in Formulation Using Surface Response Methodology

Separations, 2022
A combination of antibiotics and antiprotozoal and antisecretory medicines has been prescribed for the treatment of diarrhea. A rapid, reproducible liquid chromatographic procedure was established for the concurrent analysis of metronidazole (MET ...
Mahesh Attimarad, Katharigatta Narayanaswamy Venugopala, Muhammad S. Chohan, Pottathil Shinu, Marysheela David, Effren II Plaza Molina, Anroop Balachandran Nair, Nagaraja Sreeharsha, Abdulrahman Ibrahim Altaysan, Abdulmalek Ahmed Balgoname   +9 more
doaj   +1 more source

Medication Reconciliation in Outpatient Psychiatry: An Indicator of Communication With Primary Care? A Quantitative Descriptive Study

Journal of Advanced Nursing, Volume 82, Issue 9, Page 8658-8670, September 2026.
ABSTRACT Aims To quantify medication discrepancies between an outpatient psychiatric service and general practitioners in northern France, and investigate general practitioner identification in psychiatric records. Design Quantitative, exploratory, retrospective, descriptive, monocentric study.
Gwladys Acoulon, Camille Vincent, Sixtine Brenek, Stéphane Duhem, Cédric Bachellez, Maxime Bubrovszky   +5 more
wiley   +1 more source

Comparison of racecadotril and loperamide in children with acute diarrhoea [PDF]

Alimentary Pharmacology & Therapeutics, 1999
MethodsA multicentre, parallel‐group, double‐blind, double‐placebo study was carried out to compare the efficacy, tolerability, and safety of racecadotril and loperamide in children aged 2 to 10 years who were suffering from acute diarrhoea. Patients received racecadotril (1.5 mg/kg) or loperamide (0.03 mg/kg) three times daily plus matching placebo ...
D, Turck, H, Berard, N, Fretault, J M, Lecomte   +3 more
openaire   +2 more sources

Racecadotril at the Beginning of Pediatric Gastroenteritis: A Small Experience of a Primary Level Hospital

, 2013
parents because of it does not reduce the frequency of bowel movements and the loss of fluids from the gut nor shortens the duration of the disease.
Bizzarri B., DE ANGELIS, Gian Luigi, Manfredi M   +2 more
core   +1 more source

New perspectives on acute diarrhea in the breastfed infant: racecadotril [PDF]

, 2006
El propósito del presente trabajo es realizar una puesta al día del tratamiento de la diarrea aguda del lactante, así como evaluar la efi cacia del racecadotrilo, un nuevo fármaco antisecretor intestinal, en el tratamiento de la diarrea aguda.
Maldonado Lozano, José
core   +1 more source

Multifaceted Evaluation of Syngonium podophyllum Flower Extracts: Anthelmintic, Antidiabetic, Antipyretic, and Antidiarrheal Potentials via Experimental, In Silico, and DFT Approaches

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
The methanolic extract of Syngonium podophyllum flower demonstrated significant anthelmintic, antidiabetic, antidiarrheal, and antipyretic effects across all in vitro and in vivo experimental models. Furthermore, in silico studies revealed that these phytoconstituents exhibit favorable pharmacokinetic properties, interact with key therapeutic target ...
Mahathir Mohammad, Nusrat Jahan Moon, Md. Hossain Rasel, Md. Anisul Islam, Nazmul Hasan Eshaque, Md. Jahirul Islam Mamun, Md. Zamil Hossain, Md. Mahmudul Hasan, Md. Tanvir Chowdhury, S. M. Moazzem Hossen   +9 more
wiley   +1 more source

A new dissolution medium for racecadotril molecule and analytical method validation [PDF]

, 2023
Rasekadotril ishal rahatsızlıklarının tedavisinde kullanılan asetorfan etkin metabolitine sahip olan moleküldür. Ancak molekül yapısından dolayı organik çözücülerde çok iyi çözünürken sulu ortamlardaki çözünürlüğü çok düşük seviyelerde kalmaktadır ...
Çakır, Onur
core   +1 more source

Rethinking the AI Paradigm for Solubility Prediction of Drug‑Like Compounds with Dual‐Perspective Modeling and Experimental Validation

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Aqueous solubility governs drug delivery and bioavailability, yet its prediction remains challenging. Utilizing the largest curated dataset of drug‐like molecules, prediction models are constructed through dual‐perspective benchmarking. Stacking methods outperform advanced deep learning due to data constraints. These validated models enabled systematic
Qilin Zhu, Yuxin Qiu, Guzhong Chen, Wenyao Chen, Xiang Zhang, Zhiwen Qi, Xuezhi Duan, De Chen, Zhen Song   +8 more
wiley   +1 more source

Racecadotril versus placebo in the treatment of acute diarrhoea in adults [PDF]

Alimentary Pharmacology & Therapeutics, 1999
MethodsA two‐centre, double‐blind, parallel‐group, randomized study was carried out to compare the efficacy and tolerability of racecadotril (100 mg three times daily) and placebo in 70 adult patients with acute diarrhoea. An objective criterion of antisecretory activity, stool weight, was used.ResultsRacecadotril produced a significant (P = 0.025 ...
H, Hamza, H, Ben Khalifa, P, Baumer, H, Berard, J M, Lecomte   +4 more
openaire   +2 more sources

Role of Racecadotril in Children with Acute Diarrhea

Dhaka Shishu (Children) Hospital Journal, 2021
Background: Diarrhea is a leading cause of illness and death among children in developing countries. Racecadotril (acetorphan), an enkephalinase inhibitor with antisecretory and anti-diarrheal actions, is an effective and safe treatment for acute diarrhea in adults and children.
Sheikh Farjana Sonia, Sharmin Afroze, Kazi Iman, Uzzal Kumar Ghosh, Shahidul Islam, Parijat Bishwas, Azmeri Sultana   +6 more
openaire   +1 more source