Results 51 to 60 of about 511 (145)

Effect of racecadotril as an adjunct to standard therapy and standard therapy alone on the duration of hospital stay in children aged 6–60 months with acute watery diarrhea

Journal of Social & Health Sciences
Acute watery diarrhea (AWD) is a significant contributor to morbidity as well as mortality among underfive children, predominantly in resource-limited settings.
Hassan Jamil, Hafiza Saima Pracha, Rafia Jamil, Faheem Afzal, Umer Ameer Paracha   +4 more
doaj   +1 more source

Patch tests in non‐immediate cutaneous adverse drug reactions: Late readings on Day 4 is more sensitive than on Day 3

Contact Dermatitis, Volume 91, Issue 4, Page 321-326, October 2024.
Our study shows that a second reading at D4 (24.9%) enchances the sensitivity of a first reading at D3 (13.7%) for the patients' positivity of PTs with suspect drugs in the exploration of NICADR (p < 0.0001). Late readings should not be carried out on D3 because of an important loss of sensibility compared to D4.
Ilaria Matei, Thomas Bettuzzi, Amandine Weill, Gwendeline Gener, Kamar Bel Hareth, Fleck Margaux, Muriel Verlinde‐Carvalho, Muriel Paul, Saskia Ingen‐Housz‐Oro, Haudrey Assier   +9 more
wiley   +1 more source

Opioid Facilitation of β-Adrenergic Blockade: A New Pharmacological Condition?

Pharmaceuticals, 2015
Recently, propranolol was suggested to prevent hyperlactatemia in a child with hypovolemic shock through β-adrenergic blockade. Though it is a known inhibitor of glycolysis, propranolol, outside this observation, has never been reported to fully protect ...
Joseph Vamecq, Karine Mention-Mulliez, Francis Leclerc, Dries Dobbelaere   +3 more
doaj   +1 more source

Long term outcomes in children with trichohepatoenteric syndrome

American Journal of Medical Genetics Part A, Volume 194, Issue 2, Page 141-149, February 2024.
Abstract Trichohepatoenteric syndrome (THES) is a rare autosomal recessive disorder caused by mutations in either TTC37 or SKIV2L, usually leading to congenital diarrhea as part of a multisystem disease. Here, we report on the natural history of the disease for the largest UK cohort of patients with THES from 1996 to 2020.
Kwang Yang Lee, Ronald Bremner, Jane Hartley, Sue Protheroe, Wolfram Haller, Tracey Johnson, Lisa Whyte   +6 more
wiley   +1 more source

Role of Antidiarrhoeal Drugs as Adjunctive Therapies for Acute Diarrhoea in Children

International Journal of Pediatrics, 2013
Acute diarrhoea is a leading cause of child mortality in developing countries. Principal pathogens include Escherichia coli, rotaviruses, and noroviruses. 90% of diarrhoeal deaths are attributable to inadequate sanitation.
Christophe Faure
doaj   +1 more source

Protein Kinase Inhibitors Indicated for Lung Cancer: Pharmacodynamics, Pharmacokinetics, Adverse Drug Reactions, and Evaluation in Clinical Trials

Journal of Clinical Pharmacy and Therapeutics, Volume 2024, Issue 1, 2024.
WhatIs Known and Objective. Anti‐EGFR (epidermal growth factor receptor) drugs are indicated for non‐small‐cell lung cancer (NSCLC). This review summarises the information available to date on the first anti‐EGFRs granted market authorisation: erlotinib TARCEVA®, gefitinib IRESSA®, afatinib GIOTRIF®, dacomitinib VIZIMPRO®, and osimertinib TAGRISSO ...
Constance Bordet, Vincent Dongay, Yoann Zelmat, Julien Mazieres, Fabien Despas, Samuel Silvestre   +5 more
wiley   +1 more source

Is racecadotril effective for acute diarrhea in children?

Medwave, 2015
La gastroenteritis o diarrea aguda es una enfermedad habitualmente autolimitada, pero consume recursos sanitarios y constituye un motivo de consulta frecuente en pediatría. El racecadotrilo, un inhibidor de la encefalinasa intestinal, se ha usado como tratamiento porque disminuiría la duración de la diarrea y la pérdida de líquidos, pero no hay ...
Josefina Sáez, Lorena Cifuentes
openaire   +2 more sources

FORMULATION AND EVALUATION OF RACECADOTRIL MUCOADHESIVE MICROSPHERES

International Journal of Pharmacy and Pharmaceutical Sciences, 2019
Objective: To develop and evaluate the mucoadhesive microsphere using combinations of natural polymers chitosan and xanthan gum for sustained release. Methods: In the present work mucoadhesive microspheres were prepared by using natural polymers like chitosan and xanthan gum by using the emulsion chemical cross-linking method.
KANCHAN JAMKAR, SWATI MUTHA, SHARWAREE HARDIKAR, NIKHIL KUMBHAR   +3 more
openaire   +2 more sources

NOROVIRUS INFECTION (SYSTEMATIC REVIEW)

Журнал инфектологии, 2018
The share of norovirus infection is 17–20% of all cases of acute gastroenteritis in the world. The dominant II genogroup of noroviruses is characterized by rapid variability.
N. I. Khokhlova, D. V. Kapustin, E. I. Krasnova, I. Ya. I.Yа. Izvekova   +3 more
doaj   +1 more source

Adherence to treatment guidelines for acute diarrhoea in children up to 12 years in Ujjain, India - a cross-sectional prescription analysis

BMC Infectious Diseases, 2011
Background Diarrhoea accounts for 20% of all paediatric deaths in India. Despite WHO recommendations and IAP (Indian Academy of Paediatrics) and Government of India treatment guidelines, few children suffering from acute diarrhoea in India receive low ...
Marrone Gaetano, Pathak Ashish, Pathak Deepali, Diwan Vishal, Lundborg Cecilia   +4 more
doaj   +1 more source