Results 51 to 60 of about 131 (115)

Effect of racecadotril as an adjunct to standard therapy and standard therapy alone on the duration of hospital stay in children aged 6–60 months with acute watery diarrhea

Journal of Social & Health Sciences
Acute watery diarrhea (AWD) is a significant contributor to morbidity as well as mortality among underfive children, predominantly in resource-limited settings.
Hassan Jamil, Hafiza Saima Pracha, Rafia Jamil, Faheem Afzal, Umer Ameer Paracha   +4 more
doaj   +1 more source

Opioid Facilitation of β-Adrenergic Blockade: A New Pharmacological Condition?

Pharmaceuticals, 2015
Recently, propranolol was suggested to prevent hyperlactatemia in a child with hypovolemic shock through β-adrenergic blockade. Though it is a known inhibitor of glycolysis, propranolol, outside this observation, has never been reported to fully protect ...
Joseph Vamecq, Karine Mention-Mulliez, Francis Leclerc, Dries Dobbelaere   +3 more
doaj   +1 more source

Protein Kinase Inhibitors Indicated for Lung Cancer: Pharmacodynamics, Pharmacokinetics, Adverse Drug Reactions, and Evaluation in Clinical Trials

Journal of Clinical Pharmacy and Therapeutics, Volume 2024, Issue 1, 2024.
WhatIs Known and Objective. Anti‐EGFR (epidermal growth factor receptor) drugs are indicated for non‐small‐cell lung cancer (NSCLC). This review summarises the information available to date on the first anti‐EGFRs granted market authorisation: erlotinib TARCEVA®, gefitinib IRESSA®, afatinib GIOTRIF®, dacomitinib VIZIMPRO®, and osimertinib TAGRISSO ...
Constance Bordet, Vincent Dongay, Yoann Zelmat, Julien Mazieres, Fabien Despas, Samuel Silvestre   +5 more
wiley   +1 more source

Role of Antidiarrhoeal Drugs as Adjunctive Therapies for Acute Diarrhoea in Children

International Journal of Pediatrics, 2013
Acute diarrhoea is a leading cause of child mortality in developing countries. Principal pathogens include Escherichia coli, rotaviruses, and noroviruses. 90% of diarrhoeal deaths are attributable to inadequate sanitation.
Christophe Faure
doaj   +1 more source

NOROVIRUS INFECTION (SYSTEMATIC REVIEW)

Журнал инфектологии, 2018
The share of norovirus infection is 17–20% of all cases of acute gastroenteritis in the world. The dominant II genogroup of noroviruses is characterized by rapid variability.
N. I. Khokhlova, D. V. Kapustin, E. I. Krasnova, I. Ya. I.Yа. Izvekova   +3 more
doaj   +1 more source

Adherence to treatment guidelines for acute diarrhoea in children up to 12 years in Ujjain, India - a cross-sectional prescription analysis

BMC Infectious Diseases, 2011
Background Diarrhoea accounts for 20% of all paediatric deaths in India. Despite WHO recommendations and IAP (Indian Academy of Paediatrics) and Government of India treatment guidelines, few children suffering from acute diarrhoea in India receive low ...
Marrone Gaetano, Pathak Ashish, Pathak Deepali, Diwan Vishal, Lundborg Cecilia   +4 more
doaj   +1 more source

FORMULATION AND EVALUATION OF RACECADOTRIL MUCOADHESIVE MICROSPHERES

International Journal of Pharmacy and Pharmaceutical Sciences, 2019
Objective: To develop and evaluate the mucoadhesive microsphere using combinations of natural polymers chitosan and xanthan gum for sustained release. Methods: In the present work mucoadhesive microspheres were prepared by using natural polymers like chitosan and xanthan gum by using the emulsion chemical cross-linking method.
KANCHAN JAMKAR, SWATI MUTHA, SHARWAREE HARDIKAR, NIKHIL KUMBHAR   +3 more
openaire   +2 more sources

Cost utility, budget impact, and scenario analysis of racecadotril in addition to oral rehydration for acute diarrhea in children in Malaysia

ClinicoEconomics and Outcomes Research, 2018
Tamlyn Anne Rautenberg,1,2 Ute Zerwes,3 Way Seah Lee4 1IGES Institut GmbH, Berlin, Germany; 2Health Economics and HIV/AIDS Research Division (HEARD), University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa; 3Assessment in Medicine GmbH, Lö ...
Rautenberg TA, Zerwes U, Lee WS
doaj  

Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: A systematic review and network meta-analysis.

PLoS ONE, 2018
BackgroundMany interventions have shown effectiveness in reducing the duration of acute diarrhea and gastroenteritis (ADG) in children. Yet, there is lack of comparative efficacy of interventions that seem to be better than placebo among which, the ...
Ivan D Florez, Areti-Angeliki Veroniki, Reem Al Khalifah, Juan J Yepes-Nuñez, Javier M Sierra, Robin W M Vernooij, Jorge Acosta-Reyes, Claudia M Granados, Giordano Pérez-Gaxiola, Carlos Cuello-Garcia, Adriana M Zea, Yuan Zhang, Naghmeh Foroutan, Gordon H Guyatt, Lehana Thabane   +14 more
doaj   +1 more source

Is racecadotril effective for acute diarrhea in children?

Medwave, 2015
La gastroenteritis o diarrea aguda es una enfermedad habitualmente autolimitada, pero consume recursos sanitarios y constituye un motivo de consulta frecuente en pediatría. El racecadotrilo, un inhibidor de la encefalinasa intestinal, se ha usado como tratamiento porque disminuiría la duración de la diarrea y la pérdida de líquidos, pero no hay ...
Josefina Sáez, Lorena Cifuentes
openaire   +2 more sources