Results 31 to 40 of about 511 (145)

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena 脑啡肽酶和脑啡肽酶抑制剂对葡萄糖稳态的影响:一个有争议的观点和有前景的领域

Journal of Diabetes, Volume 15, Issue 5, Page 397-408, May 2023., 2023
Highlights Neprilysin (NEP) inhibitors may lead to beneficial effects through inhibition of NEP, which involves impairment of glucose homeostasis through modulation of insulin resistance and the development of pancreatic β cell dysfunction as observed in type 2 diabetes mellitus.
Faisal Holil AlAnazi, Hayder M. Al‐kuraishy, Ali I. Al‐Gareeb, Athanasios Alexiou, Marios Papadakis, Hanan A. Ogaly, Yousef Abud Alanazi, Hebatallah M. Saad, Gaber El‐Saber Batiha   +8 more
wiley   +1 more source

Racecadotril

Reactions Weekly, 2006
europepmc   +3 more sources

Evaluating the Efficacy of Racecadotril in Combination with Oral Rehydration in Children with Acute Diarrhoea: A Randomised Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Acute watery diarrhoea in early childhood frequently necessitates hospital admission. Although Oral Rehydration Salts (ORS) with zinc effectively prevent and treat dehydration, they do not consistently shorten illness duration or reduce ...
Uddhava V Kinhal, V Vidhyadhar, N Supriya   +2 more
doaj   +1 more source

Clinical Characteristics and Safety Profiles of Japanese Psoriasis Patients Who Continued Apremilast Treatment for 6 and 12 Months: A Post Hoc Analysis of an Apremilast Postmarketing Surveillance Study. [PDF]

J Dermatol
ABSTRACT Apremilast is a phosphodiesterase 4 inhibitor approved for moderate to severe psoriasis in Japan. Apremilast significantly improved Physician's Global Assessment (PGA) and Dermatology Life Quality Index (DLQI) both at 6 and 12 months in a previously published primary post‐surveillance study.
Ohtsuki M, Okubo Y, Saeki H, Igarashi A, Imafuku S, Abe M, Saito K, Ogawa R, Morita A.   +8 more
europepmc   +2 more sources

Prescribing pattern for acute diarrhea in children: A survey of pediatricians from Maharashtra, India

Muller Journal of Medical Sciences and Research, 2022
Context: Irrational use of medications for acute diarrhea in children is rampant. We conducted this survey to analyze prescription practices among pediatricians for acute diarrhea and their deviation from standard treatment guidelines.
Vikram S Patra, Jeetendra B Gavhane, Priyanka S Amonkar   +2 more
doaj   +1 more source

The effectiveness of racecadotril in the treatment of rotavirus infection in children

Aktualʹnaâ Infektologiâ, 2020
The article deals with the effectiveness of the use of racecadotril preparation as a pathogenetic agent in the treatment of rotavirus infection in children. There were 40 patients under the age of 5 years with rotavirus infection under observation.
I.I. Nezghoda, O.M. Naumenko, A.A. Asaulenko, O.S. Onofriichuk, L.M. Brovinska, A.M. Kolesnyk, O.V. Nikulchenko, N.I. Sinchuk   +7 more
doaj   +1 more source

Comparison of racecadotril and loperamide in children with acute diarrhoea [PDF]

Alimentary Pharmacology & Therapeutics, 1999
MethodsA multicentre, parallel‐group, double‐blind, double‐placebo study was carried out to compare the efficacy, tolerability, and safety of racecadotril and loperamide in children aged 2 to 10 years who were suffering from acute diarrhoea. Patients received racecadotril (1.5 mg/kg) or loperamide (0.03 mg/kg) three times daily plus matching placebo ...
D, Turck, H, Berard, N, Fretault, J M, Lecomte   +3 more
openaire   +2 more sources

Multivariate Optimization of Chromatographic Conditions for Rapid Simultaneous Quantification of Antidiarrheal Drugs in Formulation Using Surface Response Methodology

Separations, 2022
A combination of antibiotics and antiprotozoal and antisecretory medicines has been prescribed for the treatment of diarrhea. A rapid, reproducible liquid chromatographic procedure was established for the concurrent analysis of metronidazole (MET ...
Mahesh Attimarad, Katharigatta Narayanaswamy Venugopala, Muhammad S. Chohan, Pottathil Shinu, Marysheela David, Effren II Plaza Molina, Anroop Balachandran Nair, Nagaraja Sreeharsha, Abdulrahman Ibrahim Altaysan, Abdulmalek Ahmed Balgoname   +9 more
doaj   +1 more source

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2162-2170, July 2026.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Racecadotril versus placebo in the treatment of acute diarrhoea in adults [PDF]

Alimentary Pharmacology & Therapeutics, 1999
MethodsA two‐centre, double‐blind, parallel‐group, randomized study was carried out to compare the efficacy and tolerability of racecadotril (100 mg three times daily) and placebo in 70 adult patients with acute diarrhoea. An objective criterion of antisecretory activity, stool weight, was used.ResultsRacecadotril produced a significant (P = 0.025 ...
H, Hamza, H, Ben Khalifa, P, Baumer, H, Berard, J M, Lecomte   +4 more
openaire   +2 more sources