Results 21 to 30 of about 131 (115)

Racecadotril for acute diarrhoea in children [PDF]

Cochrane Database of Systematic Reviews, 2019
Acute diarrhoea is a leading cause of death for children under five years of age. Most deaths are caused by excessive fluid and electrolyte losses. Racecadotril is an anti-secretory drug that has been used for acute diarrhoea in children as an adjunct to oral rehydration therapy.To assess the efficacy and safety of racecadotril for treating acute ...
Liang, Yi, Zhang, Lingli, Zeng, Linan, Gordon, Morris, Wen, Jin   +4 more
openaire   +2 more sources

Recent progress in orodispersible films‐mediated therapeutic applications: A review

MedComm – Biomaterials and Applications, Volume 2, Issue 2, June 2023., 2023
The current therapeutic applications of orodispersible films (ODFs) are delivered either locally or systemically for potential patients suffering from various diseases, including oral inflammation, cardiovascular diseases, pain disorders, nausea and vomiting, mood or mental disorders, erectile dysfunction and pulmonary diseases Abstract Orodispersible ...
Yu Tian, Jiangtao Lin, Hongshu Jing, Quan Wang, Zhihua Wu, Yourong Duan   +5 more
wiley   +1 more source

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena 脑啡肽酶和脑啡肽酶抑制剂对葡萄糖稳态的影响:一个有争议的观点和有前景的领域

Journal of Diabetes, Volume 15, Issue 5, Page 397-408, May 2023., 2023
Highlights Neprilysin (NEP) inhibitors may lead to beneficial effects through inhibition of NEP, which involves impairment of glucose homeostasis through modulation of insulin resistance and the development of pancreatic β cell dysfunction as observed in type 2 diabetes mellitus.
Faisal Holil AlAnazi, Hayder M. Al‐kuraishy, Ali I. Al‐Gareeb, Athanasios Alexiou, Marios Papadakis, Hanan A. Ogaly, Yousef Abud Alanazi, Hebatallah M. Saad, Gaber El‐Saber Batiha   +8 more
wiley   +1 more source

Evaluating the Efficacy of Racecadotril in Combination with Oral Rehydration in Children with Acute Diarrhoea: A Randomised Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Acute watery diarrhoea in early childhood frequently necessitates hospital admission. Although Oral Rehydration Salts (ORS) with zinc effectively prevent and treat dehydration, they do not consistently shorten illness duration or reduce ...
Uddhava V Kinhal, V Vidhyadhar, N Supriya   +2 more
doaj   +1 more source

Racecadotril in the treatment of acute diarrhea in children: a systematic, comprehensive review and meta-analysis of randomized controlled trials

BMC Pediatrics, 2018
Background Racecadotril is a guideline-recommended option for the treatment of acute diarrhea in children but existing guidelines and previous reviews of the field are based on a small fraction of published evidence.
Marion Eberlin, Min Chen, Tobias Mueck, Jan Däbritz   +3 more
doaj   +1 more source

Understanding the Anti-Diarrhoeal Properties of Incomptines A and B: Antibacterial Activity against Vibrio cholerae and Its Enterotoxin Inhibition

Pharmaceuticals, 2022
Incomptines A (IA) and B (IB) are two sesquiterpene lactones with antiprotozoal, antibacterial, cytotoxic, antitumor, spermicidal, and phytotoxic properties.
Fernando Calzada, Elihu Bautista, Sergio Hidalgo-Figueroa, Normand García-Hernández, Claudia Velázquez, Elizabeth Barbosa, Miguel Valdes, Jesús Iván Solares-Pascasio   +7 more
doaj   +1 more source

Prescribing pattern for acute diarrhea in children: A survey of pediatricians from Maharashtra, India

Muller Journal of Medical Sciences and Research, 2022
Context: Irrational use of medications for acute diarrhea in children is rampant. We conducted this survey to analyze prescription practices among pediatricians for acute diarrhea and their deviation from standard treatment guidelines.
Vikram S Patra, Jeetendra B Gavhane, Priyanka S Amonkar   +2 more
doaj   +1 more source

The effectiveness of racecadotril in the treatment of rotavirus infection in children

Aktualʹnaâ Infektologiâ, 2020
The article deals with the effectiveness of the use of racecadotril preparation as a pathogenetic agent in the treatment of rotavirus infection in children. There were 40 patients under the age of 5 years with rotavirus infection under observation.
I.I. Nezghoda, O.M. Naumenko, A.A. Asaulenko, O.S. Onofriichuk, L.M. Brovinska, A.M. Kolesnyk, O.V. Nikulchenko, N.I. Sinchuk   +7 more
doaj   +1 more source

Multivariate Optimization of Chromatographic Conditions for Rapid Simultaneous Quantification of Antidiarrheal Drugs in Formulation Using Surface Response Methodology

Separations, 2022
A combination of antibiotics and antiprotozoal and antisecretory medicines has been prescribed for the treatment of diarrhea. A rapid, reproducible liquid chromatographic procedure was established for the concurrent analysis of metronidazole (MET ...
Mahesh Attimarad, Katharigatta Narayanaswamy Venugopala, Muhammad S. Chohan, Pottathil Shinu, Marysheela David, Effren II Plaza Molina, Anroop Balachandran Nair, Nagaraja Sreeharsha, Abdulrahman Ibrahim Altaysan, Abdulmalek Ahmed Balgoname   +9 more
doaj   +1 more source

National Consensus for the Management of Acute Gastroenteritis in Jordanian Children: Consensus Recommendations Endorsed by the Jordanian Paediatric Society

International Journal of Pediatrics, 2022
Diarrhoeal diseases are one of the leading worldwide preventable causes of death among children under 5 years of age. Almost half of children do not receive optimal acute gastroenteritis (AGE) treatment in Jordan.
Mohammed Rawashdeh, Basim Al-Zoubi, Maha Barbar Aliwat, Salma Burayzat, Esam Alhindawi, Ali Attia Al-Matti, Eyad Altamimi   +6 more
doaj   +1 more source