Results 21 to 30 of about 661 (153)

Recent progress in orodispersible films‐mediated therapeutic applications: A review

open access: yesMedComm – Biomaterials and Applications, Volume 2, Issue 2, June 2023., 2023
The current therapeutic applications of orodispersible films (ODFs) are delivered either locally or systemically for potential patients suffering from various diseases, including oral inflammation, cardiovascular diseases, pain disorders, nausea and vomiting, mood or mental disorders, erectile dysfunction and pulmonary diseases Abstract Orodispersible ...
Yu Tian   +5 more
wiley   +1 more source

Impact of clinically tested NEP/ACE inhibitors on tumor uptake of [111In-DOTA]MG11 [PDF]

open access: yes, 2016
Background: We have recently shown that treatment of mice with the neutral endopeptidase (NEP) inhibitor phosphoramidon (PA) improves the bioavailability and tumor uptake of biodegradable radiopeptides.
Jong, M. (Marion) de   +6 more
core   +5 more sources

Racecadotril for acute diarrhoea in children [PDF]

open access: yesCochrane Database of Systematic Reviews, 2019
Acute diarrhoea is a leading cause of death for children under five years of age. Most deaths are caused by excessive fluid and electrolyte losses. Racecadotril is an anti-secretory drug that has been used for acute diarrhoea in children as an adjunct to oral rehydration therapy.To assess the efficacy and safety of racecadotril for treating acute ...
Liang, Yi   +4 more
openaire   +2 more sources

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena 脑啡肽酶和脑啡肽酶抑制剂对葡萄糖稳态的影响:一个有争议的观点和有前景的领域

open access: yesJournal of Diabetes, Volume 15, Issue 5, Page 397-408, May 2023., 2023
Highlights Neprilysin (NEP) inhibitors may lead to beneficial effects through inhibition of NEP, which involves impairment of glucose homeostasis through modulation of insulin resistance and the development of pancreatic β cell dysfunction as observed in type 2 diabetes mellitus.
Faisal Holil AlAnazi   +8 more
wiley   +1 more source

Treatment of Acute Diarrhoea: Past and Now [PDF]

open access: yes, 2015
Context: Since ancient times diarrhoea has been a highly fatal disease and even today diarrhoea, the topic of this review, is a problem affecting millions of people around the world despite the efforts of governments and professionals from the medical ...
Caramia, Giuseppe   +3 more
core   +2 more sources

Evaluating the Efficacy of Racecadotril in Combination with Oral Rehydration in Children with Acute Diarrhoea: A Randomised Controlled Trial [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Acute watery diarrhoea in early childhood frequently necessitates hospital admission. Although Oral Rehydration Salts (ORS) with zinc effectively prevent and treat dehydration, they do not consistently shorten illness duration or reduce ...
Uddhava V Kinhal   +2 more
doaj   +1 more source

Understanding the Anti-Diarrhoeal Properties of Incomptines A and B: Antibacterial Activity against Vibrio cholerae and Its Enterotoxin Inhibition

open access: yesPharmaceuticals, 2022
Incomptines A (IA) and B (IB) are two sesquiterpene lactones with antiprotozoal, antibacterial, cytotoxic, antitumor, spermicidal, and phytotoxic properties.
Fernando Calzada   +7 more
doaj   +1 more source

Persistent diarrhea: still an important challenge for the pediatrician [PDF]

open access: yes, 2011
OBJECTIVE: To provide recent guidelines to reduce the incidence of diarrheal diseases. We discuss the definition, clinical aspects, pathophysiology, diagnosis, management, and prevention of persistent diarrhea.
Andrade, Jacy Alves Braga de   +1 more
core   +1 more source

Prescribing pattern for acute diarrhea in children: A survey of pediatricians from Maharashtra, India

open access: yesMuller Journal of Medical Sciences and Research, 2022
Context: Irrational use of medications for acute diarrhea in children is rampant. We conducted this survey to analyze prescription practices among pediatricians for acute diarrhea and their deviation from standard treatment guidelines.
Vikram S Patra   +2 more
doaj   +1 more source

Sacubitril and valsartan fixed combination to reduce heart failure events in post-acute myocardial infarction patients [PDF]

open access: yes, 2017
Heart failure is a term used to define a constellation of symptoms and signs that are commonly attributed to the inability of the heart to produce a cardiac output that meets the demands of the body. It remains a deadly disease, affecting between 1-2% of
Lang, C. C., Zaid Iskandar, M.
core   +2 more sources

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