Results 11 to 20 of about 131 (115)

Randomized Clinical Trial Comparing The Effect Of Oral Rehydration Therapy With And Without Racecadotril In The Management Of Acute Diarrhea In Children

open access: yesJournal of Rawalpindi Medical College, 2023
Objective: This study aimed to investigate the beneficial effect of racecadotril in children with acute diarrheal illness. Methods: This randomized case-control study was conducted at Watim General Hospital over four months from April to July 2023.
Sughra Zulfiqar   +5 more
doaj   +1 more source

Enhancement of dissolution rate of racecadotril by liquisolid compact technology

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2023
The current investigation was used to improve the rate of dissolution of an anti-diarrheal drug i.e., racecadotril (RT) at low pH conditions (i.e., in the stomach) by reducing the water secretion and electrolyte in to the intestine by liquisolid tablets.
Bhaskar Daravath, Shalini Somalanka
doaj   +1 more source

Integrating metabolomics, bionics, and culturomics to study probiotics-driven drug metabolism

open access: yesFrontiers in Pharmacology, 2023
Many drugs have been shown to be metabolized by the human gut microbiome, but probiotic-driven drug-metabolizing capacity is rarely explored. Here, we developed an integrated metabolomics, culturomics, and bionics framework for systematically studying ...
Bohai Li   +17 more
doaj   +1 more source

APPLICATION OF HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD FOR SIMULTANEOUS DETERMINATION OF RACECADOTRIL AND OFLOXACIN IN THEIR PHARMACEUTICAL DOSAGE FORM [PDF]

open access: yesAl-Azhar Journal of Pharmaceutical Sciences, 2019
 Racecadotril and ofloxacin are co-formulated for treatment of acute symptomatic diarrhea. In the present work RP-HPLC method was developed for simultaneous determination of racecadotril and ofloxacin in the combined dosage form.
Mohamed Kamel
doaj   +1 more source

Design, synthesis, and evaluation of novel racecadotril-tetrazole-amino acid derivatives as new potent analgesic agents

open access: yesResearch in Pharmaceutical Sciences, 2021
Background and purpose: Although pain is one of the most common symptoms of diseases, it is often mismanaged due to limited access to painkillers and ineffectiveness, unacceptable side effects, or the possibility of abuse.
Mehdi Asadi   +5 more
doaj   +1 more source

Randomized trial to assess the efficacy and safety of xyloglucan for the treatment of acute gastroenteritis in children

open access: yesFood Science &Nutrition, Volume 11, Issue 12, Page 7698-7706, December 2023., 2023
Xyloglucan is effective and safe in moderate‐to‐severe diarrhea in children 3 months to 5 years. Abstract Acute gastroenteritis is one of the most common diseases in children and an important cause of morbidity and mortality worldwide. No specific treatment is available; therefore, management is exclusively symptomatic.
Maria Jose Perez‐Garcia   +17 more
wiley   +1 more source

Concomitant medication in patients with bradykinin‐mediated angioedema – there's more than ACE inhibitors

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 21, Issue 11, Page 1283-1289, November 2023., 2023
Summary Bradykinin‐mediated angioedema is a rare, non‐allergic, potentially life‐threatening disease. ACE inhibitor‐induced angioedema and hereditary angioedema (HAE) are the two most common presentations. Therapeutic options, pathophysiology and diagnosis continue to be investigated, with considerable progress in HAE over the last few decades. For all
Robin Lochbaum   +3 more
wiley   +1 more source

ACUTE GASTROENTERITIS IN CHILDREN-THERAPEUTIC PRINCIPLES [PDF]

open access: yesRomanian Journal of Pediatrics, 2008
This report presents updated recommendations for the optimal management of acute gastroenteritis in childhood, according to fundamental therapeutical principles recommended by ESPGHAN ( European Society of Paediatric Gastroenterology, Hepatology and ...
Victoria Hurduc   +4 more
doaj   +1 more source

Medikamente als Auslöser Bradykinin‐vermittelter Angioödeme – mehr als ACE‐Hemmer

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 21, Issue 11, Page 1283-1290, November 2023., 2023
Zusammenfassung Bradykinin‐vermittelte Angioödeme sind seltene, nichtallergische und potenziell lebensbedrohliche Krankheiten. Die beiden bekanntesten Formen sind das ACE‐Hemmer‐induzierte Angioödem und das hereditäre Angioödem (HAE). Die therapeutischen Möglichkeiten, die Pathophysiologie und die Diagnostik werden weiter erforscht, wobei beim HAE in ...
Robin Lochbaum   +3 more
wiley   +1 more source

Hospital Based Prospective Observational Study to Audit the Prescription Practices and Outcomes of Paediatric Patients (6 months to 5 years age group) Presenting with Acute Diarrhea [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Diarrhea is a leading killer of children, accounting for 9% of all deaths among under-five children worldwide. WHO protocol deviation in management of diarrheas in children is likely due to various reasons.
Tapobrata De   +2 more
doaj   +1 more source

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