Results 1 to 10 of about 661 (153)
A Comprehensive Review of the Pharmacodynamics, Pharmacokinetics, and Clinical Effects of the Neutral Endopeptidase Inhibitor Racecadotril [PDF]
Frontiers in Pharmacology, 2012 Racecadotril, via its active metabolite thiorphan, is an inhibitor of the enzyme neutral endopeptidase (NEP, EC 3.4.24.11), thereby increasing exposure to NEP including enkephalins and atrial natriuretic peptide.
Marion Eberlin, Martin C Michel
exaly +10 more sources
Analysis of Racecadotril in Pharmaceutical Formulations Using Ultra Performance Liquid Chromatography (UPLC) Method [PDF]
Bezmiâlem Science, 2023 Objective:In this study, a simple and selective ultra-performance liquid chromatography method for the determination of racecadotril in pharmaceutical dosage forms has been developed.Methods:The method is in reverse phase C18 column; based on the ...
Armağan ÖNAL, Emrullah BİNAY
doaj +2 more sources
Randomized Clinical Trial Comparing The Effect Of Oral Rehydration Therapy With And Without Racecadotril In The Management Of Acute Diarrhea In Children [PDF]
Journal of Rawalpindi Medical College, 2023 Objective: This study aimed to investigate the beneficial effect of racecadotril in children with acute diarrheal illness. Methods: This randomized case-control study was conducted at Watim General Hospital over four months from April to July 2023.
Sughra Zulfiqar +5 more
doaj +3 more sources
Integrating metabolomics, bionics, and culturomics to study probiotics-driven drug metabolism [PDF]
Frontiers in Pharmacology, 2023 Many drugs have been shown to be metabolized by the human gut microbiome, but probiotic-driven drug-metabolizing capacity is rarely explored. Here, we developed an integrated metabolomics, culturomics, and bionics framework for systematically studying ...
Bohai Li +17 more
doaj +3 more sources
Frontiers in Medicine, 2016 Racecadotril is a guideline-recommended treatment to alleviate symptoms of acute diarrhea. A systematic review of randomized studies was performed comparing efficacy and safety of treatment with racecadotril to that with placebo or active treatments in ...
Marion Eberlin
exaly +3 more sources
Racecadotril induced bilateral uveal effusion: a case report
BMC OphthalmologyBackground Uveal effusion is a sight threatening condition, due to possible acute angle-closure glaucoma and maculopathy. We present a case of bilateral uveal effusion after taking racecadotril, an enkephalinase inhibitor used as a medical treatment for ...
Jona Callaert +2 more
exaly +2 more sources
Talanta OpenExperimental design beats the conventional one variable at a time (OVAT) to improve the chromatographic separations with lowest consumption of resources and maximum acceptable results for the separated peaks.
Ghada A Sedik +2 more
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Racecadotril : A Novel Antidiarrheal [PDF]
Medical Journal Armed Forces India, 2008 N, Singh, S, Narayan
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Al-Azhar Assiut Medical Journal, 2022 Background and aim Previous studies have shown that Racecadotril is safer and more effective in treating children with acute diarrhea. This study aimed to evaluate the effect of Racecadotril as a booster to oral rehydration solution in the management of ...
Reham M Sayed +2 more
doaj +1 more source
Enhancement of dissolution rate of racecadotril by liquisolid compact technology
Brazilian Journal of Pharmaceutical Sciences, 2023 The current investigation was used to improve the rate of dissolution of an anti-diarrheal drug i.e., racecadotril (RT) at low pH conditions (i.e., in the stomach) by reducing the water secretion and electrolyte in to the intestine by liquisolid tablets.
Bhaskar Daravath, Shalini Somalanka
doaj +1 more source