Results 1 to 10 of about 131 (115)

Greenness assessment profile of experimentally designed chromatographic method for the simultaneous analysis of ofloxacin and racecadotril in the presence of racecadotril impurities

open access: yesTalanta Open
Experimental design beats the conventional one variable at a time (OVAT) to improve the chromatographic separations with lowest consumption of resources and maximum acceptable results for the separated peaks.
Hala E Zaazaa   +2 more
exaly   +4 more sources

A Comprehensive Review of the Pharmacodynamics, Pharmacokinetics, and Clinical Effects of the Neutral Endopeptidase Inhibitor Racecadotril

open access: yesFrontiers in Pharmacology, 2012
Racecadotril, via its active metabolite thiorphan, is an inhibitor of the enzyme neutral endopeptidase (NEP, EC 3.4.24.11), thereby increasing exposure to NEP including enkephalins and atrial natriuretic peptide.
Martin Michel, Michel Martin C
exaly   +3 more sources

A Comprehensive Comparison of the Efficacy and Tolerability of Racecadotril with Other Treatments of Acute Diarrhea in Adults

open access: yesFrontiers in Medicine, 2016
Racecadotril is a guideline-recommended treatment to alleviate symptoms of acute diarrhea. A systematic review of randomized studies was performed comparing efficacy and safety of treatment with racecadotril to that with placebo or active treatments in ...
Viola Andresen   +2 more
exaly   +3 more sources

Racecadotril Versus Loperamide for Acute Diarrhea of Infectious Origin in Adults: A Systematic Review and Meta‐Analysis

open access: yesHealth Science Reports
Background and Aims Loperamide and racecadotril are two antidiarrheal medications with different mechanisms of action that are highly important for the treatment of diarrhea as a result of infectious pathology.
Maryam Aziz   +12 more
doaj   +2 more sources

Racecadotril induced bilateral uveal effusion: a case report

open access: yesBMC Ophthalmology
Background Uveal effusion is a sight threatening condition, due to possible acute angle-closure glaucoma and maculopathy. We present a case of bilateral uveal effusion after taking racecadotril, an enkephalinase inhibitor used as a medical treatment for ...
Joachim Van Calster   +1 more
exaly   +2 more sources

Racecadotril in the management of diarrhea: an underestimated therapeutic option?

open access: yesTherapeutic Advances in Gastroenterology
Acute infectious diarrhea (AID) represents an important clinical entity both regarding morbidity and mortality rates, even in industrialized countries, and it leads to one of the major public health burdens, among gastroenterological diseases, with ...
Luca Gallelli   +2 more
exaly   +2 more sources

Racecadotril : A Novel Antidiarrheal [PDF]

open access: yesMedical Journal Armed Forces India, 2008
N, Singh, S, Narayan
exaly   +3 more sources

Application of High-Performance Thin-layer Chromatographic Method for Simultaneous Determination of Co-formulated Ofloxacin and Racecadotril in their Oral Dosage Form [PDF]

open access: yesJournal of Advanced Pharmacy Research, 2020
Objectives: This study aimed to develop and validate a simple, rapid, economical, precise and accurate HPTLC method for simultaneous determination of ofloxacin and racecadotril has been developed.
Nasr El-Abasawi   +4 more
doaj   +1 more source

Analysis of Racecadotril in Pharmaceutical Formulations Using Ultra Performance Liquid Chromatography (UPLC) Method

open access: yesBezmiâlem Science, 2023
Objective:In this study, a simple and selective ultra-performance liquid chromatography method for the determination of racecadotril in pharmaceutical dosage forms has been developed.Methods:The method is in reverse phase C18 column; based on the ...
Armağan ÖNAL, Emrullah BİNAY
doaj   +1 more source

Role of antisecretory drug in treatment of children with acute watery diarrhea: A Randomized Controlled Trial

open access: yesAl-Azhar Assiut Medical Journal, 2022
Background and aim Previous studies have shown that Racecadotril is safer and more effective in treating children with acute diarrhea. This study aimed to evaluate the effect of Racecadotril as a booster to oral rehydration solution in the management of ...
Reham M Sayed   +2 more
doaj   +1 more source

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