Results 41 to 50 of about 131 (115)

Role of Racecadotril in Children with Acute Diarrhea

Dhaka Shishu (Children) Hospital Journal, 2021
Background: Diarrhea is a leading cause of illness and death among children in developing countries. Racecadotril (acetorphan), an enkephalinase inhibitor with antisecretory and anti-diarrheal actions, is an effective and safe treatment for acute diarrhea in adults and children.
Sheikh Farjana Sonia, Sharmin Afroze, Kazi Iman, Uzzal Kumar Ghosh, Shahidul Islam, Parijat Bishwas, Azmeri Sultana   +6 more
openaire   +1 more source

Development and Validation of a High Performance Liquid Chromatography Method for the Determination of Bromopride in the Presence of Methylparaben and Propylparaben in Pharmaceutical Formulations

SEPARATION SCIENCE PLUS, Volume 8, Issue 11, November 2025.
ABSTRACT A reversed‐phase high‐performance liquid chromatography method was developed and validated for the determination of bromopride (BROP) in the presence of methylparaben and propylparaben, using isocratic mode, C18 chromatographic column, mobile phase composed of acetonitrile and aqueous phase previously acidified with phosphoric acid to pH 3.5 ...
Francielli Gelatti Bortoly Carvalho, Patrícia Espinosa dos Santos, Elaine de Oliveira Araújo, Marcos Serrou do Amaral, Teófilo Fernando Mazon Cardoso, Nájla Mohamad Kassab   +5 more
wiley   +1 more source

Clinical Characteristics and Safety Profiles of Japanese Psoriasis Patients Who Continued Apremilast Treatment for 6 and 12 Months: A Post Hoc Analysis of an Apremilast Postmarketing Surveillance Study

The Journal of Dermatology, Volume 52, Issue 6, Page 1059-1065, June 2025.
ABSTRACT Apremilast is a phosphodiesterase 4 inhibitor approved for moderate to severe psoriasis in Japan. Apremilast significantly improved Physician's Global Assessment (PGA) and Dermatology Life Quality Index (DLQI) both at 6 and 12 months in a previously published primary post‐surveillance study.
Mamitaro Ohtsuki, Yukari Okubo, Hidehisa Saeki, Atsuyuki Igarashi, Shinichi Imafuku, Masatoshi Abe, Katsuya Saito, Ryuichi Ogawa, Akimichi Morita   +8 more
wiley   +1 more source

Evaluating the cost utility of racecadotril for the treatment of acute watery diarrhea in children: the RAWD model

ClinicoEconomics and Outcomes Research, 2012
Tamlyn Anne Rautenberg1,2, Ute Zerwes1, Douglas Foerster3,4, Rick Aultman51Assessment in Medicine GmbH, Lörrach, Germany; 2Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom; 3Abbott Products Operations AG, Allschwil,
Rautenberg TA, Zerwes U, Foerster D, Aultman R   +3 more
doaj  

Efficacy of Oral Racecadotril in Children with Acute Watery Diarrhea

Pakistan Armed Forces Medical Journal
Objective: To determine the efficacy of Racecadotril in treating acute watery diarrhea among children under 5 years of age attending Combined Military Hospital, Rawalpindi Pakistan. Study Design: Quasi-experimental study. Place and Duration of Study:
Rida Tahir, Muhammad Tariq Nadeem, Hira Javed, Maryam Ijaz   +3 more
doaj   +1 more source

Determination of racecadotril by HPLC in capsules

Indian Journal of Pharmaceutical Sciences, 2007
A simple, precise and rapid RP-HPLC method was developed for the determination of racecadotril in a pharmaceutical formulation using gemfibrozil as internal standard. Ratio of the peak area of analyte to internal standard was used for quantification. The chromatographic separation was carried out by using a Reverse Phase C18 column (BDS-Hypersil).
A Shirwaikar, SL Prabu, T Singh, A Joseph, CDinesh Kumar   +4 more
openaire   +1 more source

Hereditary angioedema in children: Review and practical perspective for clinical management

Pediatric Allergy and Immunology, Volume 35, Issue 12, December 2024.
Abstract Background Hereditary angioedema (HAE) in children has specific features and requires multidisciplinary management. Methods We performed a literature search and underwent in‐depth discussions to provide practical tools for physicians. Results HAE is a rare, life‐threatening genetic disorder.
Anne Pagnier, Angelina Dermesropian, Charlotte Kevorkian‐Verguet, Mélisande Bourgoin‐Heck, Cyrille Hoarau, Héloïse Reumaux, Frédérique Nugues, Christine Audouin‐Pajot, Sibylle Blanc, Aurélia Carbasse, Anne‐Laure Jurquet, Mélanie Voidey, Mona Villedieu, Laurence Bouillet, Isabelle Boccon‐Gibod   +14 more
wiley   +1 more source

Analysis of factors influencing the overall effect of racecadotril on childhood acute diarrhea. Results from a real-world and post-authorization surveillance study in Venezuela

Therapeutics and Clinical Risk Management, 2010
Jose ChacónOn behalf of the Racecadotril Post-authorization Record Group; Centro Clinico Profesional Caracas, Caracas, VenezuelaAbstract: Drug efficacy might differ from clinical trial results when performed in clinical daily conditions ...
Jose Chacón
doaj  

Patch tests in non‐immediate cutaneous adverse drug reactions: Late readings on Day 4 is more sensitive than on Day 3

Contact Dermatitis, Volume 91, Issue 4, Page 321-326, October 2024.
Our study shows that a second reading at D4 (24.9%) enchances the sensitivity of a first reading at D3 (13.7%) for the patients' positivity of PTs with suspect drugs in the exploration of NICADR (p < 0.0001). Late readings should not be carried out on D3 because of an important loss of sensibility compared to D4.
Ilaria Matei, Thomas Bettuzzi, Amandine Weill, Gwendeline Gener, Kamar Bel Hareth, Fleck Margaux, Muriel Verlinde‐Carvalho, Muriel Paul, Saskia Ingen‐Housz‐Oro, Haudrey Assier   +9 more
wiley   +1 more source

Long term outcomes in children with trichohepatoenteric syndrome

American Journal of Medical Genetics Part A, Volume 194, Issue 2, Page 141-149, February 2024.
Abstract Trichohepatoenteric syndrome (THES) is a rare autosomal recessive disorder caused by mutations in either TTC37 or SKIV2L, usually leading to congenital diarrhea as part of a multisystem disease. Here, we report on the natural history of the disease for the largest UK cohort of patients with THES from 1996 to 2020.
Kwang Yang Lee, Ronald Bremner, Jane Hartley, Sue Protheroe, Wolfram Haller, Tracey Johnson, Lisa Whyte   +6 more
wiley   +1 more source