Results 71 to 80 of about 701 (178)

Patch tests in non‐immediate cutaneous adverse drug reactions: Late readings on Day 4 is more sensitive than on Day 3

open access: yesContact Dermatitis, Volume 91, Issue 4, Page 321-326, October 2024.
Our study shows that a second reading at D4 (24.9%) enchances the sensitivity of a first reading at D3 (13.7%) for the patients' positivity of PTs with suspect drugs in the exploration of NICADR (p < 0.0001). Late readings should not be carried out on D3 because of an important loss of sensibility compared to D4.
Ilaria Matei   +9 more
wiley   +1 more source

Effect of racecadotril as an adjunct to standard therapy and standard therapy alone on the duration of hospital stay in children aged 6–60 months with acute watery diarrhea

open access: yesJournal of Social & Health Sciences
Acute watery diarrhea (AWD) is a significant contributor to morbidity as well as mortality among underfive children, predominantly in resource-limited settings.
Hassan Jamil   +4 more
doaj   +1 more source

Opioid Facilitation of β-Adrenergic Blockade: A New Pharmacological Condition?

open access: yesPharmaceuticals, 2015
Recently, propranolol was suggested to prevent hyperlactatemia in a child with hypovolemic shock through β-adrenergic blockade. Though it is a known inhibitor of glycolysis, propranolol, outside this observation, has never been reported to fully protect ...
Joseph Vamecq   +3 more
doaj   +1 more source

DataSheet1_Integrating metabolomics, bionics, and culturomics to study probiotics-driven drug metabolism.DOCX

open access: yes, 2023
Many drugs have been shown to be metabolized by the human gut microbiome, but probiotic-driven drug-metabolizing capacity is rarely explored. Here, we developed an integrated metabolomics, culturomics, and bionics framework for systematically studying ...
Dandan Wang (286632)   +5 more
core   +1 more source

Long term outcomes in children with trichohepatoenteric syndrome

open access: yesAmerican Journal of Medical Genetics Part A, Volume 194, Issue 2, Page 141-149, February 2024.
Abstract Trichohepatoenteric syndrome (THES) is a rare autosomal recessive disorder caused by mutations in either TTC37 or SKIV2L, usually leading to congenital diarrhea as part of a multisystem disease. Here, we report on the natural history of the disease for the largest UK cohort of patients with THES from 1996 to 2020.
Kwang Yang Lee   +6 more
wiley   +1 more source

Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled, proof-of-concept trial. [PDF]

open access: yesBr J Pharmacol, 2019
BACKGROUND AND PURPOSE: Pulmonary arterial hypertension (PAH) is an incurable, incapacitating disorder resulting from increased pulmonary vascular resistance, pulmonary arterial remodeling and right ventricular failure.
Hobbs AJ   +14 more
europepmc   +3 more sources

Role of Antidiarrhoeal Drugs as Adjunctive Therapies for Acute Diarrhoea in Children

open access: yesInternational Journal of Pediatrics, 2013
Acute diarrhoea is a leading cause of child mortality in developing countries. Principal pathogens include Escherichia coli, rotaviruses, and noroviruses. 90% of diarrhoeal deaths are attributable to inadequate sanitation.
Christophe Faure
doaj   +1 more source

Protein Kinase Inhibitors Indicated for Lung Cancer: Pharmacodynamics, Pharmacokinetics, Adverse Drug Reactions, and Evaluation in Clinical Trials

open access: yesJournal of Clinical Pharmacy and Therapeutics, Volume 2024, Issue 1, 2024.
WhatIs Known and Objective. Anti‐EGFR (epidermal growth factor receptor) drugs are indicated for non‐small‐cell lung cancer (NSCLC). This review summarises the information available to date on the first anti‐EGFRs granted market authorisation: erlotinib TARCEVA®, gefitinib IRESSA®, afatinib GIOTRIF®, dacomitinib VIZIMPRO®, and osimertinib TAGRISSO ...
Constance Bordet   +5 more
wiley   +1 more source

Validated RP-HPLC Method For Simultaneous Estimation of Ofloxacin and Racecadotril in Bulk and Combined Pharmaceutical Formulations [PDF]

open access: yes, 2023
Combined drug dosage forms are highly used since they can target more than one disease. For Ofloxacin and Racecadotril in bulk and combined dosage form a simple ,accurate and precise stability indicating simultaneous method was developed and validated by
Das, Debashree Debasish, Chawla, Pooja
core  

Table2_Integrating metabolomics, bionics, and culturomics to study probiotics-driven drug metabolism.XLSX

open access: yes, 2023
Many drugs have been shown to be metabolized by the human gut microbiome, but probiotic-driven drug-metabolizing capacity is rarely explored. Here, we developed an integrated metabolomics, culturomics, and bionics framework for systematically studying ...
Dandan Wang (286632)   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy