Results 21 to 30 of about 89,874 (280)

Racemic N-methyl-4-[2-(methylsulfanyl)pyrimidin-4-yl]-1-(tetrahydrofuran-3-yl)-1H-pyrazol-5-amine

Acta Crystallographica Section E, 2009
The title compound, C13H17N5OS, was obtained by cycloaddition of 2-[2-(methylsulfanyl)pyrimidin-4-yl]-3-oxopropanenitrile with (tetrahydrofuran-3-yl)hydrazine dihydrochloride and subsequent N-methylation of 4-[2-(methylsulfanyl)pyrimidin-4-yl]-1 ...
Alex Yanovsky, Antonio DiPasquale, Arnold L. Rheingold, Kevin K.-C. Liu, Zhengyu Liu   +4 more
doaj   +1 more source

Racemic tricarbonyl(η6-7-methoxyflavan)chromium(0)

Acta Crystallographica Section E, 2010
In the title compound [systematic name: tricarbonyl(η6-7-methoxy-2-phenyl-3,4-dihydro-2H-1-benzopyran)chromium(0)], [Cr(C16H16O2)(CO)3], the Cr(CO)3 unit is coordinated by the phenylene ring of the flavan ligand, exhibiting a three-legged piano ...
Johannes. H. van Tonder, Barend C. B. Bezuidenhoudt, J. Marthinus Janse van Rensburg   +2 more
doaj   +1 more source

Redox-enabled direct stereoconvergent heteroarylation of simple alcohols

Nature Communications, 2021
Synthesizing complex structures of high enantiomeric excess from racemic feedstock is an enduring challenge. Here, the authors couple racemic secondary alcohols with pyrroles to form enantioenriched 2-substituted heteroarenes, via a borrowing hydrogen ...
Yongbing Liu, Ran Tao, Zhi-Keng Lin, Guoqiang Yang, Yu Zhao   +4 more
doaj   +1 more source

A Review of the Metabolism and Relevance to Form and Formulation of Ketamine

European Psychiatry, 2023
Introduction Ketamine is a phenylcyclohexylamine derivative comprising a racemic mixture of S- and R-ketamine that possesses anesthetic, analgesic, anti-inflammatory, and antidepressant activity.
P. Chue, A. Andreiev, J. Chue, J. Chue, M. Tate   +4 more
doaj   +1 more source

Mirror symmetry breaking with limited enantioselective autocatalysis and temperature gradients: a stability survey

, 2012
We analyze limited enantioselective (LES) autocatalysis in a temperature gradient and with internal flow/recycling of hot and cold material. Microreversibility forbids broken mirror symmetry for LES in the presence of a temperature gradient alone.
Blanco, Celia, Crusats, Joaquim, El-Hachemi, Zoubir, Hochberg, David, Moyano, Albert, Ribó, Josep M.   +5 more
core   +1 more source

Correction: de Gonzalo, G. Lipase Catalysed Kinetic Resolution of Racemic 1,2-Diols Containing a Chiral Quaternary Center. Molecules 2018, 23, 1585 [PDF]

, 2018
n/
Gonzalo Calvo, Gonzalo de
core   +1 more source

Racemic (RSC,SRS)-(2-{[1-allyloxycarbonyl-3-(methylsulfanyl)propyl]iminomethyl}phenyl-κ3S,N,C1)chloridoplatinum(II)

Acta Crystallographica Section E, 2009
The title compound, [Pt(C15H18NO2S)Cl], was obtained by the cyclometallation reaction of cis-bis(benzonitrile)dichloridoplatinum(II) with N-benzylidene-l-methionine allyl ester in refluxing toluene. The PtII atom has a square-planar geometry and is tetra-
Katsuhiro Isozaki, Akira Sato, Kazushi Miki   +2 more
doaj   +1 more source

Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application. [PDF]

, 2017
Chiral α,β-unsaturated acylammonium salts are novel dienophiles enabling enantioselective Diels-Alder-lactonization (DAL) organocascades leading to cis- and trans-fused, bicyclic γ- and δ-lactones from readily prepared dienes, commodity acid chlorides ...
Abbasov, Mikail E, Hudson, Brandi M, Romo, Daniel, Tantillo, Dean J   +3 more
core   +2 more sources

Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014–2019) [PDF]

, 2019
The broad interdisciplinary nature of biocatalysis fosters innovation, as different technical fields are interconnected and synergized. A way to depict that innovation is by conducting a survey on patent activities.
Alcántara, Andrés R., Domínguez de María, Pablo, Gonzalo Calvo, Gonzalo de   +2 more
core   +3 more sources

Ethyl 4-[(2-hydroxyethyl)amino]-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

IUCrData
In the title compound, C17H22N2O5 the pyrrolidine ring is almost planar and subtends a dihedral angle of 85.77 (7)° with the pendant phenyl ring. An intramolecular N—H...O hydrogen bond generates an S(6) loop. In the crystal, the compound forms inversion
Fatin Nur Ain Abdul Rashid, Mohd Fazli Mohammat, Mohd Abdul Fatah Abdul Manan, Ayisy Amirul Afti Bakhtiar Afendy, David B. Cordes, Aidan P. McKay   +5 more
doaj   +1 more source