Results 31 to 40 of about 89,874 (280)

Chiral Separation of rac-Propylene Oxide on Penicillamine Coated Gold NPs

Nanomaterials, 2020
The surfaces of chemically synthesized spherical gold NPs (Au-NPs) have been modified using chiral L- or D-penicillamine (Pen) in order to impart enantioselective adsorption properties.
Nisha Shukla, Zachary Blonder, Andrew J. Gellman   +2 more
doaj   +1 more source

Kinetic Resolution in Asymmetric Epoxidation using Iminium Salt Catalysis [PDF]

, 2013
The first reported examples of kinetic resolution in epoxidation reactions using iminium salt catalysis are described, providing up to 99% ee in the epoxidation of racemic cis ...
Allin, Steven M., Appleby, Louise F., Buckley, Benjamin R., Bulman Page, Philip C., Chan, Yohan, Day, David P., Mckenzie, Michael J., Slawin, Alexandra M. Z.   +7 more
core   +1 more source

Racemic dielectric metasurfaces for arbitrary terahertz polarization rotation and wavefront manipulation

Opto-Electronic Advances
Dielectric chiral metasurface is a new type of planar and efficient chiral optical device that shows strong circular dichroism or optical activity, which has important application potential in optical sensing and display. However, the two types of chiral
Jie Li, Xueguang Lu, Hui Li, Chunyu Song, Qi Tan, Yu He, Jingyu Liu, Li Luo, Tingting Tang, Tingting Liu, Hang Xu, Shuyuan Xiao, Wanxia Huang, Yun Shen, Yan Zhang, Yating Zhang, Jianquan Yao   +16 more
doaj   +1 more source

Pharmacological Profile of MP-101, a Novel Non-racemic Mixture of R- and S-dimiracetam with Increased Potency in Rat Models of Cognition, Depression and Neuropathic Pain

Cells, 2022
The racemic mixture dimiracetam negatively modulates NMDA-induced glutamate release in rat spinal cord synaptosomal preparations and is orally effective in models of neuropathic pain.
Tiziana Bonifacino, Laura Micheli, Carola Torazza, Carla Ghelardini, Carlo Farina, Giambattista Bonanno, Marco Milanese, Lorenzo Di Cesare Mannelli, Michael W. Scherz   +8 more
doaj   +1 more source

Focus on chirality of HIV-​1 non-​nucleoside reverse transcriptase inhibitors [PDF]

, 2016
Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
core   +2 more sources

Multicyclic D‐Stereospecific Hydrolase Dimer With High Sustained Activity

Angewandte Chemie, EarlyView.
Protein macrocyclization was applied to a thermally unstable D‐stereospecific hydrolase using in situ cyclization of proteins (INCYPRO). This site‐specific cross‐linking approach enhanced the resistance of the enzyme to heat and cosolvents.
Anissa Haim, Sandra Liebscher, Rasmus Klintrot, Lorenzo Vallino, Marcelo Masman, Andreas H. Simon, Marianne Hahn, Sven Hennig, Saskia Neubacher, Frank Bordusa, Tom N. Grossmann   +10 more
wiley   +2 more sources

Ethyl (2RS,3SR,4RS)-1-ethyl-2-(furan-2-yl)-4-hydroxy-5-oxopyrrolidine-3-carboxylate

IUCrData
The title racemic oxopyrrolidine compound, C13H17NO5, contains three stereogenic centres and crystallizes with two molecules in the asymmetric unit. The five-membered pyrrolidine rings in both molecules exhibit envelope conformations.
Nor Habibah Mohd Rosli, Mohd Fazli Mohammat, Mohd Abdul Fatah Abdul Manan, David B. Cordes, Aidan P. McKay   +4 more
doaj   +1 more source

Chemoselective Sequential Polymerization: An Approach Toward Mixed Plastic Waste Recycling

Advanced Functional Materials, EarlyView.
Inspired by biological protein metabolism, this study demonstrates the closed‐loop recycling of mixed synthetic polymers via ring‐closing depolymerization followed by a chemoselective sequential polymerizations process. The approach recovers pure polymers from mixed feedstocks, even in multilayer formats, highlighting a promising strategy to overcome a
Gadi Slor, Youwei Ma, Hyunwoo Park, Tae‐Lim Choi, Damien Guironnet, Francesco Stellacci   +5 more
wiley   +1 more source

Predicting and Rationalizing Piezoelectricity in Racemic Bioorganic Molecular Crystals

Angewandte Chemie, EarlyView.
Racemic molecular crystals, composed of equal mixtures of chiral enantiomeric components, are predicted to exhibit significant piezoelectric responses and favourable mechanical flexibility. This study identifies organic and bioorganic racemates as promising candidates for sustainable, lead‐free materials, enabling next‐generation applications in energy
Shubham Vishnoi, Sarah Guerin
wiley   +2 more sources

Racemic 2′-hydroxy-4′,4′-dimethylpyran-1,5-dihydroxyxanthone monohydrate

Acta Crystallographica Section E, 2013
The title xanthone (systematic name: 3,6,11-trihydroxy-1,1-dimethyl-2,3-dihydrochromeno[2,3-f]chromen-7-one monohydrate), known as pruniflorone N, crystallized as a monohydrate, C18H16O6·H2O.
Nawong Boonnak, Suchada Chantrapromma, Hoong-Kun Fun   +2 more
doaj   +1 more source