Results 101 to 110 of about 781,700 (285)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Tell me your date of birth, and I will tell you how good you are in orienteering

Frontiers in Sports and Active Living
Orienteering is a sport where participants must choose the best route between control points marked on the map, combining it with their displacement capacity. It combines endurance running with mental capacity.
Alberto Ferriz-Valero, Alberto Ferriz-Valero, Javier Montiel-Bontmatí, Ove Østerlie, Ove Østerlie, Juan Pedro Caraça-Valente, Alberto Mínguez-Viñambres, Héctor Esteve-Ibáñez   +7 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

A Case Study on the Development of a High-Intensity Interval Training Set for a National-Level Middle-Distance Swimmer: The Conception of the Faster-than-Race Pace Test Set

Journal of Functional Morphology and Kinesiology
Background: Swimming coaches search for the most efficient training approach and stimuli for swimmers’ improvement. High-intensity interval training (HIIT) is a well-established training approach used by coaches to accelerate swimmers’ improvement.
Konstantinos Papadimitriou, Sousana K. Papadopoulou, Evmorfia Psara, Constantinos Giaginis   +3 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

A preliminary determination of normal accelerations on racing airplanes [PDF]

Rules and methods for insuring safe structural strength of racing airplanes used in the major air meets in this country have recently been considered.
Kirschbaum, H W, Scudder, N F
core   +1 more source

Hispanics Account for More Than Half of Nation's Growth in Past Decade [PDF]

, 2011
Highlights findings from the 2010 census data about the growth of the Latino-Hispanic population compared with other races/ethnicities as well as increases in its share of the overall population.

core  

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Close Rematches For NH Congressional Seats 10/24/2012 [PDF]

, 2012
The races for both of New Hampshire’s congressional seats remain very close as Democrats Carol Shea-Porter and Anne McLane Kuster attempt to unseat their 2010 opponents, Republicans Frank Guinta and Charlie Bass.
Survey Center, UNH
core   +1 more source