Results 81 to 90 of about 273,020 (301)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Viaje deportivo, nación y territorio. El Automóvil Club Argentino y los orígenes del Turismo Carretera.  Argentina, 1924-1938.

Nuevo mundo - Mundos Nuevos, 2008
This work focuses on a modality of motor sports in Latina America, in the period between World Wars in Argentina, paying special attention to the processes of territory formation and national identity construction.
Melina Piglia
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Impact of Gender and Race on Gastrointestinal Diseases in Patients With Parkinson's Disease: A Nationwide Analysis

JGH Open
Background Gastrointestinal (GI) diseases are common non‐motor features of Parkinson's disease (PD), significantly impacting quality of life. The impact of racial and gender disparities in this population remains underexplored.
Mohamed H. Eldesouki, Ahmed Yasser Shaban, Mohamed Mahmoud Marey, Eslam Mohammed Rabea, Abdulrhman Helal, Mohamed Seisa, Omar Abdelhalim, Hazem Abosheaishaa, Mohamed Khalaf   +8 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Annual report of the Association for the Protection of Native Races presented at the ... annual meeting held on ...

, 1900
Description based on: 19th (Mar. 11, 1930); Electronic reproduction. 1934/35. Canberra, A.C.T.
Association for the Protection of Native Races (Australia)
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Phaseolin diversity in cultivated common bean from the Caribbean Diversidad de faseolinas en frijol común cultivado del Caribe

Acta Agronómica, 2007
<span style="font-size: 10pt; font-family: Verdana">In this study, 180 genotypes of cultivated <em>Phaseolus vulgaris </em>from the Caribbean were evaluated with the phaseolin marker.
Hidalgo Rigoberto, Blair Mathew, Pantoja Wilfredo   +2 more
doaj  

Race [PDF]

Journal of Thrombosis and Haemostasis, 2017
F R, Rosendaal, P H, Reitsma
openaire   +2 more sources

What Happens When a Woman Wins an Election? Evidence from Close Races in Brazil [PDF]

, 2013
This paper analyzes the effect the gender of local policymakers on policy outcomes. Analyzing a rich dataset from Brazilian municipalities and using a regression discontinuity design, we find that municipalities ruled by female mayors have better health ...
Brollo, Fernanda, Troiano, Ugo
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