Patent Races with Dynamic Complementarity [PDF]
Recent models of multi-stage R&D have shown that a system of weak intellectual property rights may lead to faster innovation by inducing firms to share intermediate technological knowledge.
A. Blasco
core
Host-race specificity in the endemic pygmy mistletoe Korthalsella salicornioides (Viscaceae) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Plant Biology at Massey University, Palmerston North, New Zealand [PDF]
Korthalsella Tiegh. is a genus of stem hemiparasites in the family Viscaceae, represented in New Zealand by three endemic species: K. clavata, K. lindsayi, and K. salicornioides. The most host-specific is K.
Pearson, Sofie Margaret
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Replacement bearing for Rocketdyne SSME HPOTPs using alternate self-lubricating retainer materials [PDF]
Research was conducted to develop replacement bearings for the Rocketdyne Space Shuttle main engine (SSME) high pressure oxidizer turbopumps (HPOTPs). The replacement bearings consisted of standard balls and races with a special Battelle Self-Lubricating
Dufrane, K., Gleeson, J., Kannel, J.
core +1 more source
In Dobbs v. Jackson Women’s Health Organization, the U.S. Supreme Court reversed Roe v. Wade’s limits on a state’s ability to restrict, and indeed completely outlaw, abortion. The case raises fundamentally important questions about rights to reproductive autonomy, bodily integrity, sex equality, privacy, and health.
Franke, Katherine, Mar, Ria Tabacco
openaire +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
GROWTH AND DEVELOPMENT OF THE HYPOPHARYNGEAL GLANDS AND DETECTION OF ESTERASE ISOZYMES ACTIVITY IN ASSOCIATION WITH VARROA INFESTATION IN SOME HONEYBEE RACES [PDF]
N. EI-Barbary +3 more
openalex +1 more source

