Altered patterns of gene expression underlying the enhanced immunogenicity of radiation-attenuated schistosomes [PDF]
, 2008 Schistosome cercariae only elicit high levels of protective immunity against a challenge infection if they are optimally attenuated by exposure to ionising radiation that truncates their migration in the lungs.
Jason Skelton +21 more
core +2 more sources
Radiation-attenuated schistosome vaccination--a brief historical perspective. [PDF]
, 2009 The high level of protection which can be induced by vaccination of a range of hosts, from rodents to primates, with live radiation-attenuated schistosome larvae offers great promise for development of a human schistosome vaccine.
Bickle, QD, Q. D. BICKLE
core +1 more source
Protective Effects of Alpha Lipoic Acid Against Ionizing Radiation- Induced Hepatotoxicity in Rats
, 2023 Objective: Radiation is used to treat cancer but causes serious complications, such as liver toxicity. In this study, the protective effects of alpha lipoic acid against the unwanted effects of radiation used in many cancer treatments which can cause ...
Laloğlu, Abubekir +5 more
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Molecules, 2023 (1) Background: Radioprotective agents have garnered considerable interest due to their prospective applications in radiotherapy, public health medicine, and situations of large-scale accidental radiation exposure or impending radiological emergencies ...
Samafou Penabeï +4 more
doaj +1 more source
Education and Training Needs in the Radiation Sciences: Problems and Potential Solutions [PDF]
, 2015 This article provides a summary of presentations focused on critical education and training issues in radiation oncology, radiobiology and medical physics from a workshop conducted as part of the 60th Annual Meeting of the Radiation Research Society held
Deye, James +5 more
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Protective Effects of p53 Regulatory Agents Against High-LET Radiation-Induced Injury in Mice
Frontiers in Public Health, 2020 Radiation damage to normal tissues is one of the most serious concerns in radiation therapy, and the tolerance dose of the normal tissues limits the therapeutic dose to the patients.
Akinori Morita +10 more
doaj +1 more source
Further Characterization of the Mitigation of Radiation Lethality by Protective Wounding
, 2017 There continues to be a major effort in the United States to develop mitigators for the treatment of mass casualties that received high-intensity acute ionizing radiation exposures from the detonation of an improvised nuclear device during a radiological
Joy Garrett +11 more
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Radioprotection and Radiomitigation: From the Bench to Clinical Practice
Biomedicines, 2020 The development of protective agents against harmful radiations has been a subject of investigation for decades. However, effective (ideal) radioprotectors and radiomitigators remain an unsolved problem. Because ionizing radiation-induced cellular damage
Elena Obrador +5 more
doaj +1 more source
Recent advances in self-assembling redox nanoparticles as a radiation protective agent
, 2023 International audience The search for potent radiation-protective drugs for clinical use continues. Studies have, so far, focused on targeting the neutralization of radiation-generated reactive oxygen species (ROS) to protect the cells against the ...
Nagasaki, Yukio +5 more
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Anti-Apoptosis Effects of Green Tea in Diagnostic and Therapeutic Doses of Ionizing Radiation [PDF]
Iranian Journal of Medical PhysicsIntroduction: Patients who receive ionizing radiation for diagnosis or treatment may suffer side effects in normal tissues. Radioprotective agents have the potential to decrease DNA damage and free radicals produced by ionizing radiation.
Najmeh Anbiaee +7 more
doaj +1 more source