Results 231 to 240 of about 28,129 (278)

Clinical method of testing radiation-sensitizing agents in squamous cell carcinoma

Cancer, 1963
Squamous cell carcinomas of the oral cavity and oropharynx provide suitable material for the evaluation of combined chemotherapy and radiotherapy because the therapeutic results in the primary lesions and in the metastatic lesions to the neck nodes can be assayed by palpation and inspection.
Gilbert H Fletcher, Herman D Suit, C D Howe   +2 more
exaly   +3 more sources

Combined radiation-protective and radiation-sensitizing agents IV: Measurement of intracellular protector concentrations

International Journal of Radiation Oncology Biology Physics, 1989
Radiosensitization of hypoxic V79 Chinese hamster cells by 0.5 mM misonidazole at approximately 0-4 degrees C is substantially enhanced by pretreating the cells overnight with 0.1 mM buthionine sulfoximine, which lowers the cellular glutathione content to 5% of control values (from 4 mM to approximately 0.2 mM).
Cameron J Koch, C C Stobbe, C J Koch
exaly   +3 more sources

Combined radiation-protective and radiation-sensitizing agents III: Radiosensitization by misonidazole as a function of concentrations of endogenous glutathione or exogenous thiols

International Journal of Radiation Oncology Biology Physics, 1986
Radiosensitization of V79 Chinese hamster fibroblasts by 0.5 mM misonidazole is a smooth function of endogenous glutathione (GSH) levels as modulated upwards by pre-incubation in medium containing cysteamine, or downwards by pre-incubation in medium containing buthionine sulfoximine.
Cameron J Koch, C C Stobbe, C J Koch
exaly   +3 more sources

Clinical use of radiation sensitizing agents

Cancer Treatment Reviews, 1974
Malcolm A Bagshaw, D R Goffinet
exaly   +3 more sources

Effect of Radiation-Sensitizing Agents in Radiation Therapy of Mouse Mammary Carcinoma

Radiology, 1970
IUdR, injected intraperitoneally, did not cause cell death for tumor cells proliferating as small colonies in subcutaneous tissues. Only a small amount of TdR of total DNA was replaced. A small fraction of the cells seemed to be in active cell proliferation, and they efficiently utilized the injected IUdR.
H D, Suit, R, Hewitt, M, Urano
openaire   +2 more sources

An oxygenation agent and radiation sensitizer, dodecafluoropentane, for the treatment of glioblastoma multiforme.

Journal of Clinical Oncology, 2015
TPS2078 Background: Post-resected glioblastoma multiforme (GMB) patients were treated with dodecafluoropentane emulsion (DDFPe) to evaluate the pharmacokinetics (PK), safety and potential survival ...
Jason D. Lickliter, David Brown Wilson, Howard Hendrickson, Natarajan Raghunand, Soo-Peang Khor, Olivia Longacre, Evan C. Unger   +6 more
openaire   +1 more source

Radiation sensitivity of bacteria and virus in porcine xenoskin for dressing agent

Radiation Physics and Chemistry, 2012
Abstract In this study, gamma irradiation sensitivities of bacteria and viruses in porcine skin were evaluated to establish the optimum sterilization condition for the dressing material and a xenoskin graft. Escherichia coli and Bacillus subtilis were used as model pathogens and inoculated at 106–107 log CFU/g.
Eu-Ri Jo, Pil-Mun Jung, Jong-il Choi, Ju-Woon Lee   +3 more
openaire   +1 more source

Strategies for the analysis of in vitro radiation sensitivity and prediction of interaction with potential radiation modifying agents

International Journal of Radiation Biology, 2010
To better predict radiation-drug interactions in in vitro model systems, thorough assessment of the effects of in vitro exposure is required. The aim of this article is to show that both clonogenic capacity and cellular proliferation, which represent important different elements of tumour conduct, can be considered when assessing in vitro radio ...
Luttjeboer, M., Lafleur, M.V.M., Kwidama, Z.J., van Rijn, J., van den Berg, J, Slotman, B.J., Kaspers, G.J.L., Cloos, J.   +7 more
openaire   +4 more sources