Results 221 to 230 of about 28,129 (278)

Ataxia telangiectasia mutated (ATM) kinase as a predictive biomarker in clinical oncology: implications for a precision treatment approach. [PDF]

Neoplasia
Pham AT, Yuan F, Nagathihalli NS, Dosch AR.   +3 more
europepmc   +1 more source

Synthesis and Characterization of Novel Silylated Sm3+ and Eu3+ Complexes Incorporated Into Mesoporous Silica Nanoparticles

European Journal of Inorganic Chemistry, Volume 29, Issue 19, 2 July 2026.
The strategy of incorporating the Eu(tta‐Si)3(phen) and Sm(tta‐Si)3(phen)2 complexes prevented leaching of the complexes and preserved their intrinsic optical properties. Preliminary studies of silylated Ln3+ complexes and nanoparticles loaded with these complexes demonstrated cytotoxicity against cancer cells, with minimal cytotoxic effect on nontumor
Juliana Jorge, Jaqueline Rodrigues da Silva, Diego Boldo, Kristiane Fanti Del Pino Santos, Luana da Silva Oliveira, Adriana Pereira Duarte, Gustavo Rocha de Castro, Ariadna Lafourcade Prada, Jesús Rafael Rodríguez Amado, Marc Verelst, Vasilii Khripun, Marco Antonio Utrera Martines   +11 more
wiley   +1 more source

Inhibition of Focal Adhesion Restricts Chemoresistance in Pancreatic Cancer by Targeting SLC7A11 Mediated Ferroptosis

Advanced Science, Volume 13, Issue 37, 3 July 2026.
FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang, Hui Yang, Baoyuan Zhang, Yongsu Ma, Kuangen Zhang, Peng Wang, Jiapeng Yang, Zaiqi Wang, Rong Liu, Xiaodong Tian, Ning Zhang, Yinmo Yang   +11 more
wiley   +1 more source

Impact of Multimodal Oncological Therapy on Survival and Local Control in Unresectable Perihilar Cholangiocarcinoma

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background This study aimed to evaluate the safety and effectiveness of targeted multimodal oncological therapy in patients with unresectable hilar cholangiocarcinoma (HCCA) presenting with obstructive jaundice, particularly those with the nodular‐infiltrating morphological type.
Zhen Chi, Lihong Chen, Weizhu Yang, Ning Huang, Jingyao Huang, Fenglin Chen   +5 more
wiley   +1 more source

The Effect of AZD5153 on Radiosensitivity in Pancreatic Cancer Cells Through ATM-chk1 Pathway. [PDF]

Drug Des Devel Ther
Zhu L, Dong R, Yan G, Zhu H, Yan Y, Zhang B, Wang G, Lin N, Tan B.   +8 more
europepmc   +1 more source

Hydroxyflavone-Modified Aza-BODIPY Derivatives for Combined Photodynamic and CO Therapy against Neuroblastoma. [PDF]

J Med Chem
Kwangmettatam S, Uengwanarat B, Nabglang C, Mahingsadet K, Sritangos P, Muangsopa P, Saengboonmee C, Lai RY, Kamkaew A.   +8 more
europepmc   +1 more source

"Cytokine-Mediated tumor sensitization: mechanistic frameworks and therapeutic opportunities in cancer Immunotherapy". [PDF]

Clin Exp Med
Aghaei M, Bahreiny SS, Mahdizade AH, Abbasi A, Magharati A, Yousefi-Avarvand A.   +5 more
europepmc   +1 more source

Chemoresistance in gynecologic cancers: mechanistic insights and emerging platforms to overcome drug failure. [PDF]

J Ovarian Res
Garg P, Salgia R, Singhal SS.
europepmc   +1 more source

Lanthanide Nanotheranostics in Radiotherapy. [PDF]

Int J Mol Sci
Han S, Liu Y, Cai T, Liu Y, Ge-Zhang S.
europepmc   +1 more source

Effect of blueberry extract on enhancement of radiosensitivity in non-Hodgkin lymphoma by modulating proliferation and apoptosis. [PDF]

Daru
Moradloo N, Arab S, Jam HR, Asgharzadeh S, Shokri S, Nasehi L, Nokhodchi A.   +6 more
europepmc   +1 more source