Results 201 to 210 of about 15,150 (235)
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Enhancement of antitumor activity of alkylating agents by the radiation sensitizer misonidazole.
Cancer research, 1981The influence of the radiosensitizer misonidazole on the effectiveness of several alkylating agents and cis-platinum against advanced solid murine tumors was investigated. Tumor regrowth delay, frequency of tumor regressions, and animal life span were used to evaluate misonidazole in combination with cyclophosphamide, L-phenylalanine mustard, 1-(2 ...
J J, Clement +4 more
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Radiation Research, 1984
Pretreatment of V79- WNRE cells with 150 microM diethylmaleate for 1 hr at 37 degrees C caused a decrease in intracellular glutathione levels to approximately 10-15% of control levels (0.5 vs 5.0 nmol/10(6) cells). The cells could be washed free of diethylmaleate and held at 0 degree C for several hours without toxicity and with no increase in ...
C J, Koch, C C, Stobbe, E A, Bump
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Pretreatment of V79- WNRE cells with 150 microM diethylmaleate for 1 hr at 37 degrees C caused a decrease in intracellular glutathione levels to approximately 10-15% of control levels (0.5 vs 5.0 nmol/10(6) cells). The cells could be washed free of diethylmaleate and held at 0 degree C for several hours without toxicity and with no increase in ...
C J, Koch, C C, Stobbe, E A, Bump
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Radiation Research, 1981
Experiments have been done to test whether a hypoxic cell radiosensitizing agent (misonidazole) can be combined with a radioprotecting agent (cysteamine) to equalize partially the radiation response of hypoxic and aerobic mammalian cells in tissue culture.
C J, Koch, R L, Howell
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Experiments have been done to test whether a hypoxic cell radiosensitizing agent (misonidazole) can be combined with a radioprotecting agent (cysteamine) to equalize partially the radiation response of hypoxic and aerobic mammalian cells in tissue culture.
C J, Koch, R L, Howell
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Anticancer research, 1995
We studied whether cellular sensitivity to anticancer agents was correlated with a repair deficiency in three yeast epistasis groups of radiation sensitive mutants. All these mutants were hypersensitive to cisplatin and mitomycin C. By contrast, both rad51 and rad52 mutants deficient in double-strand breaks repair were hypersensitive to adriamycin and ...
H, Abe, M, Wada, K, Kohno, M, Kuwano
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We studied whether cellular sensitivity to anticancer agents was correlated with a repair deficiency in three yeast epistasis groups of radiation sensitive mutants. All these mutants were hypersensitive to cisplatin and mitomycin C. By contrast, both rad51 and rad52 mutants deficient in double-strand breaks repair were hypersensitive to adriamycin and ...
H, Abe, M, Wada, K, Kohno, M, Kuwano
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[Radiation sensitizing agents for hypoxic cells: past, present and future].
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 1999Hypoxic cells are present in rodent and xenografted human tumours and it has been known for a long time that the absence of oxygen in tumours is a factor of resistance against ionising radiation. The dose modifying role of oxygen (oxygen enhancement ratio) has been largely studied in experimental models.
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Radiation therapy‐associated toxicity: Etiology, management, and prevention
Ca-A Cancer Journal for Clinicians, 2021Kyle Wang
exaly
[Radiation-protective and radiation-sensitizing agents].
Bollettino chimico farmaceutico, 1976G, Valcurone, O, Cerri
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Insulin-sensitizing agents: use in pregnancy and as therapy in polycystic ovary syndrome
Human Reproduction Update, 2005FRANCISCO Fabregues, R Tur
exaly
Radiation-Protective Agents in Mammals
Journal of Pharmaceutical Sciences, 1969William O Foye, W O Foye
exaly