Results 201 to 210 of about 28,129 (278)

Effects of tumour necrosis factor and interleukin‐6 inhibitor therapy on exercise‐related visceral adipose tissue reduction in rheumatoid arthritis

Experimental Physiology, EarlyView.
Abstract Excess visceral adipose tissue (VAT) mass increases cardiovascular disease risk. Exercise supports overall health and VAT mass reduction in rheumatoid arthritis (RA). Unlike tumour necrosis factor (TNF), interleukin‐6 (IL‐6) is upregulated following exercise and is involved in free fatty acid mobilisation and might mediate the reduction in VAT
Simon Jønck, Malte Lund Adamsen, Iben E. Rasmussen, Anna A. Lytzen, Mathilde Løk, Morten Asp Vonsild Lund, Benjamin Nerup, Lene Wohlfahrt Dreyer, Peter G. Jørgensen, Niels Vejlstrup, Lars Køber, Søren Jacobsen, Bente Klarlund Pedersen, Helga Ellingsgaard, Pil Højgaard, Ronan M. G. Berg, Regitse Højgaard Christensen   +16 more
wiley   +1 more source

Inhibition of mitochondrial RNA polymerase sensitizes cancer cells to radiation by inhibiting mitochondrial respiration. [PDF]

J Radiat Res
Tsunoda S, Osawa Y, Hosoya N.
europepmc   +1 more source

Therapeutic potential of spexin in diabetic neuropathy: Insights from in vitro and in vivo models

Experimental Physiology, EarlyView.
Abstract The present study investigated the therapeutic potential of spexin (SPX) on both in vitro and in vivo models of diabetic neuropathy (DN). A total of 40 male BALB/c mice were randomly allocated into four experimental groups (n = 10 per group): a normoglycaemic control, an untreated DN group and two SPX treatment groups (DN+SPX‐12.5 and DN+SPX ...
Mehmet Refik Bahar, Seval Ulku Orhan, Cigdem Tekin, Asli Taslidere, Mete Ozcan, Suat Tekin   +5 more
wiley   +1 more source

Comparative Studies on the Effect of Radiation-sensitizing Agents : Used in Radiating VX2 Carcinoma, with Reference to 5-Bromodeoxyuridine (BUdR)

The Journal of the Kyushu Dental Society, 1975
openaire   +2 more sources

Lost in Translation: Why Biologic Therapies for Intervertebral Disc Degeneration and Low Back Pain Have Not Reached the Clinic (Yet)

JOR SPINE, Volume 9, Issue 3, September 2026.
From preclinical promise to clinical translation in intervertebral disc degeneration (IDD). Robust preclinical evidence supports a range of biologic therapies, with consistent improvements in imaging, extracellular matrix composition, inflammation, and behavior.
Luca Ambrosio, Jordy Schol, Clara Ruiz‐Fernandez, Vincenzo Denaro, Gianluca Vadalà, Daisuke Sakai   +5 more
wiley   +1 more source

Metabolic Radiosensitization by Targeting Lactate Metabolism with Microfluidic Liposomal Nanocarriers. [PDF]

ACS Biomater Sci Eng
Doherty M, Feng J, Wang T, Yin C, Byrne NM, Chambers S, Islam R, Lamprou DA, Coulter JA.   +8 more
europepmc   +1 more source

Nanomaterial‐Mediated Radiotherapy–Immunotherapy Combinations: Breaking Immunosuppression and Revolutionizing Cancer Treatment

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley   +1 more source

Decoding the Crosstalk Between Heat Shock Proteins and Phytochemicals in Thyroid Nodule Regression: Mechanisms and Therapeutic Implications. [PDF]

Drug Des Devel Ther
Zhang R, Lv J.
europepmc   +1 more source

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K, Pritam Kumar Roy, Maniklal Shee, Budhaditya Mukherjee, Aoife Ward Gahlawat, Mahitosh Mandal   +5 more
wiley   +1 more source

Bridging cancer therapies: the role of magnetic nanoparticles in combination cancer therapy. [PDF]

Discov Nano
Ebrahim Damavandi S, Banihashemi Jozdani SM, Elyasigorji Z, Vosough M.   +3 more
europepmc   +1 more source