Results 181 to 190 of about 15,150 (235)

Abscopal Effect in Radiation Therapy: The Immune Mechanisms and Clinical Advances

MedComm, Volume 7, Issue 9, September 2026.
The schematic outlines the key events of the abscopal effect. (Ignition) Local radiotherapy (RT) induces the release of immunogenic signals from the tumor, leading to dendritic cell (DC) activation. (Orchestration) In the tumor‐draining lymph node (TDLN), DCs prime naive T cells into cytotoxic T lymphocytes (CTLs), a process modulated by regulatory T ...
Yihong Dong, Moran Chen, Xupeng Hou, Xiaoya Tang, Xiaoli Yu, Jing Liu   +5 more
wiley   +1 more source

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K, Pritam Kumar Roy, Maniklal Shee, Budhaditya Mukherjee, Aoife Ward Gahlawat, Mahitosh Mandal   +5 more
wiley   +1 more source

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Clinical method of testing radiation-sensitizing agents in squamous cell carcinoma

Cancer, 1963
Squamous cell carcinomas of the oral cavity and oropharynx provide suitable material for the evaluation of combined chemotherapy and radiotherapy because the therapeutic results in the primary lesions and in the metastatic lesions to the neck nodes can be assayed by palpation and inspection.
H D Suit, G H Fletcher
exaly   +3 more sources

Effect of Radiation-Sensitizing Agents in Radiation Therapy of Mouse Mammary Carcinoma

Radiology, 1970
IUdR, injected intraperitoneally, did not cause cell death for tumor cells proliferating as small colonies in subcutaneous tissues. Only a small amount of TdR of total DNA was replaced. A small fraction of the cells seemed to be in active cell proliferation, and they efficiently utilized the injected IUdR.
Herman D Suit, M Urano, H D Suit
exaly   +3 more sources

Clinical use of radiation sensitizing agents

Cancer Treatment Reviews, 1974
Don R Goffinet, Malcolm A Bagshaw, D R Goffinet   +2 more
exaly   +3 more sources

An oxygenation agent and radiation sensitizer, dodecafluoropentane, for the treatment of glioblastoma multiforme.

Journal of Clinical Oncology, 2015
TPS2078 Background: Post-resected glioblastoma multiforme (GMB) patients were treated with dodecafluoropentane emulsion (DDFPe) to evaluate the pharmacokinetics (PK), safety and potential survival ...
Jason D. Lickliter, David Brown Wilson, Howard Hendrickson, Natarajan Raghunand, Soo-Peang Khor, Olivia Longacre, Evan C. Unger   +6 more
openaire   +1 more source

Radiation sensitivity of bacteria and virus in porcine xenoskin for dressing agent

Radiation Physics and Chemistry, 2012
Abstract In this study, gamma irradiation sensitivities of bacteria and viruses in porcine skin were evaluated to establish the optimum sterilization condition for the dressing material and a xenoskin graft. Escherichia coli and Bacillus subtilis were used as model pathogens and inoculated at 106–107 log CFU/g.
Eu-Ri Jo, Pil-Mun Jung, Jong-il Choi, Ju-Woon Lee   +3 more
openaire   +1 more source

Enhancement of Alkylating Agent Cytotoxicity by Radiation Sensitizers

1986
Animal tumors having a wide range of growth rates and histologies have been shown to contain hypoxic cells (1), which largely determine the radiation dose necessary for tumor control. Nonetheless, the nearly universal presence of hypoxic cells in solid tumors in rodents does not prove that the same is true of human tumors.
J. Martin Brown, David G. Hirst, Michael R. Horsman, Yvonne C. Taylor   +3 more
openaire   +1 more source

Strategies for the analysis of in vitro radiation sensitivity and prediction of interaction with potential radiation modifying agents

International Journal of Radiation Biology, 2010
To better predict radiation-drug interactions in in vitro model systems, thorough assessment of the effects of in vitro exposure is required. The aim of this article is to show that both clonogenic capacity and cellular proliferation, which represent important different elements of tumour conduct, can be considered when assessing in vitro radio ...
Luttjeboer, M., Lafleur, M.V.M., Kwidama, Z.J., van Rijn, J., van den Berg, J, Slotman, B.J., Kaspers, G.J.L., Cloos, J.   +7 more
openaire   +4 more sources

Comparison of high- and low-molecular-weight sensitizing agents causing occupational asthma: an evidence-based insight [PDF]

Expert Review of Clinical Immunology
The many substances used at the workplace that can cause sensitizer-induced occupational asthma are conventionally categorized into high-molecular-weight (HMW) agents and low-molecular-weight (LMW) agents, implying implicitly that these two categories of
Virginie Doyen, , Malo Jean-Luc
exaly   +2 more sources