Results 171 to 180 of about 28,129 (278)

Dual IRE1 targets: Determinants of the cell fate?

The FEBS Journal, EarlyView.
IRE1 is an ER stress sensor that restores protein homeostasis through two signaling activities: XBP1s, which upregulates its target gene expression or RIDD which downregulates its target transcripts. We recently identified Dual IRE1 Targets (DIT) which are modulated by both XBP1s and RIDD activities.
Eva Billat, Léane Legrand, Tony Avril, Elodie Lafont   +3 more
wiley   +1 more source

NANP targeting radiosensitizes glioblastoma through TNFR1 sialylation-driven mesenchymal shift. [PDF]

Nat Commun
Ding Y, Zhang ZY, Ezhilarasan R, Modrek AS, Graciani M, Karp J, McManus G, Jambhale A, Sulman EP.   +8 more
europepmc   +1 more source

Unmothered at Work: Organizational Silence Around Reproductive Loss

Gender, Work &Organization, EarlyView.
ABSTRACT An identity transition refers to changes in self‐concept that can result from professional or personal shifts. Although organizations increasingly support institutionally legible and culturally normative nonwork transitions, others remain professionally stigmatized or culturally unspeakable.
Katrina M. Brownell
wiley   +1 more source

Regulation of glycosylation in radiotherapy: exploring the multiple effects of DNA damage, immune response, stromal microenvironment and metabolism. [PDF]

Front Oncol
Cui W, Jiang M, Zhang R, Yu J, Chen D.
europepmc   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Cisplatin-encapsulated zeolitic imidazolate framework-8 nanosystem enhanced radiosensitivity of non-small cell lung cancer. [PDF]

Sci Rep
Yang R, Xie H, Wu H, Liu X, Luo J, Han L, Zhang M, Bao Z, Gong Y, Xie C.   +9 more
europepmc   +1 more source

Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment

Immunology &Cell Biology, EarlyView.
Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari, Farah Ahmady‐Nield, Amit Sharma, Ingo G. H. Schmidt‐Wolf, Jarek Maciaczyk, Rodney B. Luwor, Adrian A. Achuthan   +6 more
wiley   +1 more source

Radiosensitisation of Head and Neck Cancer Cells to Protons of Increasing LET Through Targeting DNA Double Strand Break Repair. [PDF]

Cells
Dufficy ER, Goula A, Melia E, Bellamy A, Parsons JL.   +4 more
europepmc   +1 more source

Feasibility and outcomes of kidney transplantation in patients with end‐stage kidney disease after haemopoietic stem cell transplantation

Internal Medicine Journal, EarlyView.
Abstract Background Advances in haemopoietic stem cell transplantation (HSCT) have improved long‐term survival, but they have also led to late complications, such as nephropathy. However, the safety and feasibility of kidney transplantation (KT) in patients with HSCT‐related end‐stage kidney disease (ESKD) remain unclear.
Bioh Kim, Seunghyeok Choi, Hanbi Lee, Hye‐Eun Yoon, Hohyung Nam, Silvia Park, Byung Ha Chung   +6 more
wiley   +1 more source

Clinical translation and landscape of stimuli-responsive nanomedicines and microscale therapeutics.

Chem Soc Rev
Kobzev D, Kulyk O, Barmin RA, Tatarets A, Pallares RM, Kiessling F, Lammers T, Peña Q.   +7 more
europepmc   +1 more source