Results 61 to 70 of about 3,644,479 (344)

Analysis of the Knowledge and Attitude of Turkish Urology Residents on the Use of Fluoroscopy Working in University Hospitals and Training and Research Hospitals: A National Survey-Based Comperative Study

open access: yesHaseki Tıp Bülteni, 2022
Aim:Tendency, knowledge, awareness, and behavior patterns of urology residents in Turkey regarding the use of fluoroscopy may vary depending on the institutions.
Samet Senel   +5 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Gamma Irradiation of Brown Rice: Effects of Dose, Variety, Paddy Age, and Packaging on Fungal Control, Shelf-Life and Post-Harvest Cost Estimate [PDF]

open access: yesJournal of Food Quality and Hazards Control
Background: Brown rice offers superior nutritional value compared to polished white rice but is less favored in rice-consuming countries due to its limited shelf-life.
G.B. Abrera   +9 more
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Irradiation and Alterations in Hippocampal DNA Methylation

open access: yesEpigenomes
The response of the brain to radiation is important for cancer patients receiving whole or partial brain irradiation or total body irradiation, those exposed to irradiation as part of a nuclear accident or a nuclear war or terrorism event, and for ...
Soren Impey, Jacob Raber
doaj   +1 more source

Heat Transfer in Directional Water Transport Fabrics

open access: yesFibers, 2016
Directional water transport fabrics can proactively transfer moisture from the body. They show great potential in making sportswear and summer clothing.
Chao Zeng   +3 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Photon versus Proton Therapy in the Management of Head and Neck Cancer: A Systematic Review

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Head and Neck Cancers (HNC), particularly Head and Neck Squamous Cell Carcinoma (HNSCC), are major causes of cancer morbidity and mortality. Radiation therapy, commonly using photons, can damage surrounding healthy tissues.
S Sowmya, R Sangavi, R Amritha Sripoo
doaj   +1 more source

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