Results 81 to 90 of about 436,480 (310)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Silicon solid state devices and radiation detection
This book addresses the fundamental principles of interaction between radiation and matter, the principles of working and the operation of particle detectors based on silicon solid state devices.
Rancoita, Pier-Giorgio, Leroy, Claude
core +1 more source
Physics and engineering of radiation detection
Physics and Engineering of Radiation Detection presents an overview of basic physics of radiation and its applications and covers the origins and properties of different kinds of ionizing radiation, their detection and measurement, and the procedures ...
Ahmed, Syed Naeem
core +1 more source
Bolometric detection of Josephson radiation
AbstractOne of the most promising approaches towards large-scale quantum computation uses devices based on many Josephson junctions. Yet, even today, open questions regarding the single junction remain unsolved, such as the detailed understanding of the quantum phase transitions, the coupling of the Josephson junction to the environment or how to ...
Bayan Karimi +5 more
openaire +9 more sources
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Computer modeling and experimental work on the astrobiological implications of the martian subsurface ionising radiation environment [PDF]
Any microbial life extant in the top meters of the martian subsurface is likely to be held dormant for long periods of time by the current permafrost conditions.
Dartnell, Lewis R, Dartnell, L.R.
core
Deformation Mechanisms of Inorganic Thermoelectric Materials with Plasticity
Flexible inorganic thermoelectric (TE) materials are beneficial to the development of wireless wearable devices due to their plasticity and high performance.
Bangzhi Ge +4 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
PLASMON EFFECTS IN SOLID-STATE RADIATION DETECTORS
We have examined the role of plasmons on the electron energy response of solid-state (Si and Ge) radiation detectors. We found that at the level of parts per thousand, internal-conversion electron calibration techniques do not suffice to yield an ...
CHOY, TC, STONEHAM, AM
core

