Results 131 to 140 of about 513,484 (358)
Advanced Materials, EarlyView.A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen +7 more
wiley +1 more source
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Advanced Materials, EarlyView.Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi +4 more
wiley +1 more source
Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance
Advanced Materials, EarlyView.This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee +14 more
wiley +1 more source
Playing Hard with Si: Challenges and Opportunities for New Materials in Radiation Therapy Dosimetry
Advanced Materials, EarlyView.Silicon has been a cornerstone material of radiation therapy dosimetry for many decades, providing somewhat unchallenged performance. However, there are caveats to its use, requiring complex designs and, often, correction factors to provide accurate measurements.
James Cayley +9 more
wiley +1 more source
Advanced Therapeutics, EarlyView.Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi +5 more
wiley +1 more source
Canadian Journal of Gastroenterology and HepatologyConclusions: The prognosis of HCC patients receiving RT was worse for those with a pre-RT serum IL-6 concentration > 7.8 pg/mL than those with a pre-RT serum IL-6 concentration ≤ 7.8 pg/mL.
Yong Hu +5 more
doaj +1 more source
A brief review of low-dose rate (LDR) and high-dose rate (HDR) brachytherapy boost for high-risk prostate [PDF]
, 2019 For patients with unfavorable or high-risk prostate cancer, dose escalated radiation therapy leads to improved progression free survival but attempts to deliver increased dose by external beam radiation therapy (EBRT) alone can be limited by late ...
Baumann, Brian C +4 more
core +1 more source
Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment
Advanced Therapeutics, EarlyView.How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley +1 more source
Advances in Radiation Oncology, 2020 Purpose: The progress of women in academic medicine appears to be curtailed. We evaluated gender differences in academia for residents in radiation oncology compared with 2 of its related specialties, radiology and medical oncology, across Canada ...
Leah Taussky +11 more
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