Results 131 to 140 of about 546,164 (358)

Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma

Advanced Science, EarlyView.
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, Jason T. Huse, Bo Chen, Timothy A. Chan, Zengxin Qi, Zhao Zhang, Xiuping Liu, Yuxiang Wang   +16 more
wiley   +1 more source

How Advances in Imaging Will Affect Precision Radiation Oncology [PDF]

, 2018
David A. Jaffray, Shiva K. Das, Paula Jacobs, Robert Jeraj, Philippe Lambin   +4 more
openalex   +1 more source

Focal Spot, Spring 1987 [PDF]

, 1987
https://digitalcommons.wustl.edu/focal_spot_archives/1045/thumbnail ...

core   +1 more source

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

Radiation Oncology

Sarcoma, 2001
  +5 more sources

182: Towards Gender Equality and Equity in Radiation Oncology: Career Entry and Exit Trends in the Canadian Radiation Oncologist Workforce with Projection Modeling to 2040

, 2020
Jaime Kwok, Nina Samson, Corinne Doll, Lisa Barbera, Shaun Loewen   +4 more
openalex   +1 more source

Partial Breast Irradiation and Surgical Clip Usage for Tumor Bed Delineation After Breast-Conserving Surgery in Canada: A Radiation Oncology Perspective [PDF]

, 2021
Christine Koch, Gemma Corey, Zhihui Amy Liu, Kathy Han, Anthony Fyles   +4 more
openalex   +1 more source

Focal Spot, Spring 1973 [PDF]

, 1973
https://digitalcommons.wustl.edu/focal_spot_archives/1005/thumbnail ...

core   +1 more source

Boosting Electrochemiluminescence of Carbon Nitrides via Molecular Capacitor‐Mediated Spatiotemporal Electron Coordination

Advanced Science, EarlyView.
Molecular capacitors are modified on carbon nitrides (CN) to dynamically regulate electron capture and accumulation in the defect states under different potentials. As a result, the electrochemiluminescence (ECL) efficiency increases by up to 100 times, owing to a new spatiotemporal coordination mechanism.
Lingling Xiang, Yuhua Hou, Wang Li, Kaiqing Wu, Kaiyuan Wang, Yu Wang, Yanfeng Fang, Songqin Liu, Yanfei Shen, Yuanjian Zhang   +9 more
wiley   +1 more source

Carbon Ion Beam Reirradiation in Recurrent High-Grade Glioma

Cancer Management and Research, 2020
Fabian Eberle, 1–4 Stefan Lautenschläger, 4 Rita Engenhart-Cabillic, 1, 3, 4 Alexandra D Jensen, 5 Barbara Carl, 6 Marco Stein, 7 Jürgen Debus, 1–3, 8–11 Henrik Hauswald 1–4, 8, 10, 11 1Department of Radiation Oncology,
Eberle F, Lautenschläger S, Engenhart-Cabillic R, Jensen AD, Carl B, Stein M, Debus J, Hauswald H   +7 more
doaj