Results 61 to 70 of about 6,899,989 (399)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Robustness of hypofractionated breast radiotherapy after breast-conserving surgery with free breathing

Frontiers in Oncology, 2023
PurposeThis study aimed to evaluate the robustness with respect to the positional variations of five planning strategies in free-breathing breast hypofractionated radiotherapy (HFRT) for patients after breast-conserving surgery.MethodsTwenty patients who
Kunzhi Chen, Wuji Sun, Tao Han, Lei Yan, Minghui Sun, Wenming Xia, Libo Wang, Yinghua Shi, Chao Ge, Xu Yang, Yu Li, Huidong Wang, Huidong Wang, Huidong Wang   +13 more
doaj   +1 more source

Hospital Quality Factors Influencing the Mobility of Patients for Radical Prostate Cancer Radiation Therapy: A National Population-Based Study. [PDF]

, 2017
PURPOSE: To investigate whether patients requiring radiation treatment are prepared to travel to alternative more distant centers in response to hospital choice policies, and the factors that influence this mobility. METHODS AND MATERIALS: We present the
Aggarwal, Ajay, Charman, Susan C, Lewis, Daniel, Mason, Malcolm, Payne, Heather, Sujenthiran, Arunan, Sullivan, Richard, van der Meulen, Jan   +7 more
core   +4 more sources

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Cochlea-sparing acoustic neuroma treatment with 4π radiation therapy. [PDF]

, 2018
PurposeThis study investigates whether 4π noncoplanar radiation therapy can spare the cochleae and consequently potentially improve hearing preservation in patients with acoustic neuroma who are treated with radiation therapy.Methods and ...
Kaprealian, Tania, Lee, Percy, Sheng, Ke, Woods, Kaley, Yang, Isaac   +4 more
core  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Early biomarkers related to secondary primary cancer risk in radiotherapy treated prostate cancer patients: IMRT versus IMAT [PDF]

, 2013
PurposeTo investigate whether rotational techniques (Volumetric Modulated Arc Therapy – VMAT) are associated with a higher risk for secondary primary malignancies compared to step-and-shoot Intensity Modulated Radiation Therapy (ss-IMRT).
Bacher, Klaus, Beels, Laurence, Bogaert, Evelien, De Meerleer, Gert, De Neve, Wilfried, FONTEYNE, VALERIE, Ost, Piet, Thierens, Hubert, Vral, Anne, Werbrouck, Joke   +9 more
core   +2 more sources

Intracoronary radiation therapy [PDF]

European Heart Journal, 2001
Over the past 15 years, despite a great deal of effort in assessing a variety of approaches, restenosis reduction has remained the most problematic complication of percutaneous transluminal coronary angioplasty (PTCA). Initial attempts focused on assessing systemic drugs including anticoagulant and antiplatelet agents, calcium antagonists and lipid ...
I. R. Crocker, K. A. Robinson, N. A. F. Chronos, Spencer B. King, Mahomed Y. Salame, Stefan Verheye   +5 more
openaire   +3 more sources

Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma: Current Trends and Controversies

Technology in Cancer Research and Treatment, 2018
Hepatocellular carcinoma is the fourth leading cause of cancer-related death worldwide. Depending on the extent of disease and competing comorbidities for mortality, multiple liver-directed therapy options exist for the treatment of hepatocellular ...
S. Schaub, P. Hartvigson, M. Lock, M. Høyer, T. Brunner, H. Cardenes, L. Dawson, Edward Y. Kim, N. Mayr, S. Lo, S. Apisarnthanarax   +10 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source