Results 151 to 160 of about 1,147,538 (315)

Oxygen Attachment Dissociation of Protonated Reserpine and Its Analogs. [PDF]

open access: yesRapid Commun Mass Spectrom
Li JG   +5 more
europepmc   +1 more source

Radical is radical, or not?

open access: yesKagaku To Seibutsu, 1986
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Highlights of SRRT History

open access: yes
Copy of speech given at Building Radical Collections: Advocacy, Access, and Alliances with SRRT and Indie Presses program on Saturday, June 28, 2025.
Kagan, Alfred
core  

El radical: Año I Número 13 - 1932 abril 17

open access: yes, 1932
Copia digital. España : Ministerio de Cultura y Deporte.
Partido Radical (Orihuela)
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

El radical: Año I Número 18 - 1932 mayo 22

open access: yes, 1932
Copia digital. España : Ministerio de Cultura y Deporte.
Partido Radical (Orihuela)
core  

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