Results 161 to 170 of about 1,411,147 (304)

Elucidating Formation Mechanisms of Inorganic Sulfates upon OH Radical Oxidation of Organosulfates via Non-Sulfur Radical Pathways: Insights from Methyl Sulfate. [PDF]

J Am Chem Soc
Zhu T, Chan SKS, Gerritz L, Nizkorodov SA, Shiraiwa M, Chan MN, Tse YS.   +6 more
europepmc   +1 more source

El radical: Año I Número 20 - 1932 junio 5

, 1932
Copia digital. España : Ministerio de Cultura y Deporte.
Partido Radical (Orihuela)
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Revisiting the Fragmentation of Ketoconazole by Positive Electrospray Ionization Tandem Mass Spectrometry and Density Functional Theory Calculations. [PDF]

Rapid Commun Mass Spectrom
Carnevale Neto F, Vessecchi R.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Radical enantioconvergent meta-C─H alkylation of pyridines. [PDF]

Sci Adv
Qin S, Gao X, Li Q, Zhang M, Lin Y, Wang M, Yang M, Wang S, Zhou Z, Gao H, Yi W, Zeng Z.   +11 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

An undecacyclic carbon-centered hydrocarbon radical: synthesis and investigation. [PDF]

Beilstein J Org Chem
Acan AS, Werner J, Podlech J.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Grid electrode technology: electrophysiological tool for cavernous nerve mapping. [PDF]

Transl Androl Urol
Burnett AL, El-Achkar A, Patel K, Lopez CAR, Ghazi A, Owen JH.   +5 more
europepmc   +1 more source