Results 191 to 200 of about 249,739 (290)

Severe Hemolysis during Primaquine Radical Cure of Plasmodium vivax Malaria: Two Systematic Reviews and Individual Patient Data Descriptive Analyses. [PDF]

Am J Trop Med Hyg, 2023
Yilma D, Groves ES, Brito-Sousa JD, Monteiro WM, Chu C, Thriemer K, Commons RJ, Lacerda MVG, Price RN, Douglas NM.   +9 more
europepmc   +1 more source

The Radical Cure of Hernia [PDF]

BMJ, 1880
openaire   +2 more sources

On the Radical Cure of Hernia [PDF]

BMJ, 1890
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Radical Cure of Plasmodium vivax With Primaquine and CYP2D6 Polymorphism in Southeast Asia. [PDF]

Clin Infect Dis
Baird JK.
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Efficacy of Primaquine for the Radical Cure of Plasmodium vivax Malaria in Northeast Myanmar and the Impact of Cytochrome P450 2D6 Genotypes. [PDF]

Clin Infect Dis
Zeng W, Liu H, Malla P, Zhao Y, Menezes L, Cao Y, Wang C, Yang Z, Cui L.   +8 more
europepmc   +1 more source

Single-Nucleotide Polymorphisms in Glucose-6-Phosphate Dehydrogenase and their Relevance for the Deployment of Primaquine as a Radical Cure for Malaria. [PDF]

Am J Trop Med Hyg, 2023
Nain M, Gill J, Mohan M, Sharma A.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Haematologic responses to primaquine used for radical cure of Plasmodium vivax in public health facilities in Ethiopia: a prospective observational study. [PDF]

Malar J
Shifraw T, Abdelmenan S, Zewde A, Worku A, Abera A, Mohammed H, Etana K, Keating J, Chibsa S, Girma S, Teka H, Mumba P, Murphy M, Karmarkar E, Price RN, Hwang J, Berhane Y.   +16 more
europepmc   +1 more source