Results 21 to 30 of about 249,739 (290)

ON THE RADICAL CURE OF HERNIA. [PDF]

Lancet, The
n ...
exaly   +2 more sources

THE RADICAL CURE OF VARICOCELE. [PDF]

Lancet, The, 1914
John O'Conor
exaly   +3 more sources

Glucose-6-Phosphate Dehydrogenase (G6PD) Measurement Using Biosensors by Community-Based Village Malaria Workers and Hospital Laboratory Staff in Cambodia: A Quantitative Study

Pathogens, 2023
Vivax malaria can relapse after an initial infection due to dormant liver stages of the parasite. Radical cure can prevent relapses but requires the measurement of glucose-6-phosphate dehydrogenase enzyme (G6PD) activity to identify G6PD-deficient ...
Bipin Adhikari, Rupam Tripura, Lek Dysoley, Thomas J. Peto, James J. Callery, Chhoeun Heng, Thy Vanda, Ou Simvieng, Sarah Cassidy-Seyoum, Kamala Thriemer, Arjen M. Dondorp, Benedikt Ley, Lorenz von Seidlein   +12 more
doaj   +1 more source

Clinical study on comprehensive treatment of gallbladder cancer [PDF]

Waike lilun yu shijian, 2023
Early detection of gallbladder cancer is difficult with poor prognosis in late stage. Although radical surgical treatment is the main method to cure gallbladder cancer at present, only less patients have radical surgery clinically.
WANG Yuanjiang, ZOU Hao
doaj   +1 more source

Reducing the risk of Plasmodium vivax after falciparum infections in co-endemic areas—a randomized controlled trial (PRIMA)

Trials, 2022
Background Plasmodium vivax forms dormant liver stages that can reactivate weeks or months following an acute infection. Recurrent infections are often associated with a febrile illness and can cause a cumulative risk of severe anaemia, direct and ...
Kamala Thriemer, Tamiru Shibru Degaga, Michael Christian, Mohammad Shafiul Alam, Benedikt Ley, Mohammad Sharif Hossain, Mohammad Golam Kibria, Tedla Teferi Tego, Dagimawie Tadesse Abate, Sophie Weston, Amalia Karahalios, Megha Rajasekhar, Julie A. Simpson, Angela Rumaseb, Hellen Mnjala, Grant Lee, Rodas Temesgen Anose, Fitsum Getahun Kidane, Adugna Woyessa, Kevin Baird, Inge Sutanto, Asrat Hailu, Ric N. Price   +22 more
doaj   +1 more source

Ultra-short course, high-dose primaquine to prevent Plasmodium vivax infection following uncomplicated pediatric malaria: A randomized, open-label, non-inferiority trial of early versus delayed treatment

International Journal of Infectious Diseases, 2023
Objectives: We aimed to assess safety, tolerability, and Plasmodium vivax relapse rates of ultra-short course (3.5 days) high-dose (1 mg/kg twice daily) primaquine (PQ) for uncomplicated malaria because of any Plasmodium species in children randomized to
Sze-Ann Woon, Brioni R. Moore, Moses Laman, Paula Tesine, Lina Lorry, Bernadine Kasian, Phantica Yambo, Gumul Yadi, William Pomat, Kevin T. Batty, Sam Salman, Leanne J. Robinson, Timothy M.E. Davis, Laurens Manning   +13 more
doaj   +1 more source

A model for malaria treatment evaluation in the presence of multiple species

Epidemics, 2023
Plasmodium falciparum and P. vivax are the two most common causes of malaria. While the majority of deaths and severe morbidity are due to P. falciparum, P.
C.R. Walker, R.I. Hickson, E. Chang, P. Ngor, S. Sovannaroth, J.A. Simpson, D.J. Price, J.M. McCaw, R.N. Price, J.A. Flegg, A. Devine   +10 more
doaj   +1 more source

Use of primaquine and glucose-6-phosphate dehydrogenase deficiency testing: Divergent policies and practices in malaria endemic countries. [PDF]

PLoS Neglected Tropical Diseases, 2018
Primaquine is the only available antimalarial drug that kills dormant liver stages of Plasmodium vivax and Plasmodium ovale malarias and therefore prevents their relapse ('radical cure').
Judith Recht, Elizabeth A Ashley, Nicholas J White   +2 more
doaj   +1 more source

Precarity at the Margins of Malaria Control in the Chittagong Hill Tracts in Bangladesh: A Mixed-Methods Study

Pathogens, 2020
Bangladesh has achieved significant progress towards malaria elimination, although health service delivery for malaria remains challenging in remote forested areas such as the Chittagong Hill Tracts (CHT).
Mohammad Abdul Matin, Nandini D. P. Sarkar, Ching Swe Phru, Benedikt Ley, Kamala Thriemer, Ric N. Price, Koen Peeters Grietens, Wasif Ali Khan, Mohammad Shafiul Alam, Charlotte Gryseels   +9 more
doaj   +1 more source

KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. [PDF]

, 2014
Preventing relapses of Plasmodium vivax malaria through a radical cure depends on use of the 8-aminoquinoline primaquine, which is associated with safety and compliance issues.
Borboa, Rachel, Campo, Brice, Chatterjee, Arnab K, Chen, Zhong, Diagana, Thierry T, Gagaring, Kerstin, Glynne, Richard J, Klooster, Els J, Kocken, Clemens HM, Kuhen, Kelli, Leroy, Didier, Luty, Adrian, McNamara, Case W, Nagle, Advait, Plouffe, David M, Remarque, Edmond J, Roland, Jason, Sauerwein, Robert, Thomas, Alan W, van Amsterdam, Sandra M, van den Berg, Alexander, van Gemert, Geert-Jan, Voorberg-van der Wel, Annemarie, Winzeler, Elizabeth A, Yeung, Bryan KS, Zeeman, Anne-Marie   +25 more
core   +1 more source