Results 101 to 110 of about 435,752 (317)
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
Synthesis of N-arylpyridinium salts bearing a nitrone spin trap as potential mitochondria-targeted antioxidants [PDF]
, 2009 The generation of excess reactive oxygen species (ROS) in mitochondria is responsible for much of the oxidative stress associated with ageing (aging), and mitochondrial dysfunction is part of the pathology of neurodegeneration and type 2 diabetes ...
Hartley, Richard C., Robertson, Linsey
core +1 more source
Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge +6 more
wiley +1 more source
Antioxidant Activity and Total Phenols in Different Extracts of Four Staphylea L. Species
Molecules, 2007 Staphylea L. is a deciduous ornamental shrub that possesses significant cytotoxic and antibacterial activity, although the chemical composition of its extracts and the identity of the structures responsible for these biological activities are not yet ...
Daniel Grancai +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source
Free Radicals and Antioxidants in Stomatology [PDF]
, 2008 Aggressive free radicals and ROS substances participate in many stamotological diseases. In the mouth these are formed or transported due to inflammation from white blood cells, in reperfusion after ischemia, cell necrosis, after bleeding in the presence
V. Holeček +4 more
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Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source
Study of the termination of two acrylonitrile radicals and infrared spectrum [PDF]
, 2014 By using the density functional theory, the study of reaction termination mechanism of two (CH3)2(CN)C-CH2-(CN)CH was carried out at the B3LYP/6-31G(d) level. The initiator AIBN was used.
Xu, C. +6 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek +14 more
wiley +1 more source
The use of bulky ligands for the stabilization of group 15 radicals and cations [PDF]
, 2002 textA variety of bulky ligands have been utilized for the stabilization of group 15 radicals and cations. The molecular structures of the stable phosphinyl and arsinyl radicals, • PnR2 (Pn = P, As; R = CH(SiMe3)2), have been determined by gas-phase ...
Wiacek, Robert Johnny
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