Results 51 to 60 of about 135,125 (299)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Algorithms for cognitive radio network and cognitive radio network cloud [PDF]
, 2021 Η πρωτοτυπία της παρούσας διατριβής έγκειται στο ότι πρότεινε και περιέγραψε ένα πλαίσιο δικτύου αναφοράς για Έλεγχο Πρόσβασης στο Μέσο για Γνωστικά Ασύρματα Δίκτυα και Νέφος και SDR Υπηρεσίες και για Έλεγχο Πρόσβασης στο Μέσο για Γνωστικά Ασύρματα Δίκτυα και Νέφος και SDR Αφηρημένες Υπηρεσίες και ολοκλήρωση τους και ανάπτυξη τους σε όλα κατά OSI ...
openaire +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
High Capacity Ethernet Radio Relay Networks in Mobile Communications
EAI Endorsed Transactions on Mobile Communications and Applications, 2018 The present paper studies the main characteristics of digital radio relays used by the largest mobile network operator (MNO) in Romania in order to develop a network supporting the newest technologies available on the market. The main contribution is the
Elena-Madalina Oproiu +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2015 Предложены методы построения программно-определяемых систем радиосвязи на основе сигнально-кодовых конструкций и расширения спектра, позволяющих увеличить надёжность радиосвязи.
Leonid O. Bondarenko +3 more
doaj
Performance of Cloud Radio Networks
CoRR, 2015 Submitted to IEEE Transactions on Wireless ...
Sreejith T. Veetil +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source