Results 151 to 160 of about 408,195 (330)

Utilization of Waste Materials Using the Müller–Kühne Process—A Life Cycle Inventory Study

open access: yesChemie Ingenieur Technik, EarlyView.
This study presents a Life Cycle Inventory of the Müller–Kühne process (MKP), which converts gypsum waste into sulfuric acid and cement clinker. The MKP outperforms conventional cement production regarding material yield, though its specific energy demand is higher. Consequently, potentials for circular gypsum waste utilization are discussed.
Leon Kassner   +4 more
wiley   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

open access: yesCytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook   +2 more
wiley   +1 more source

Population Pharmacokinetics and Exposure–Response Analyses of Momelotinib, Its Active Metabolite (M21), and Total Active Moiety in Myelofibrosis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Momelotinib, a Janus kinase (JAK) 1/JAK2/activin A receptor type 1 inhibitor, is approved for the treatment of myelofibrosis with anemia. These analyses characterized the population pharmacokinetics of momelotinib and its active metabolite M21 following administration of the commercial tablet formulation in patients with myelofibrosis from phase II/III
Benjamin Rich   +5 more
wiley   +1 more source

Evaluation of Radioactivity of the Rocks in the Foothills of the Main Caucasian Range in the Territory of Kakheti Region

open access: bronze, 2021
Eremia Tulashvili   +4 more
openalex   +2 more sources

Guided Sample Pooling in Human Mass Balance Studies: A Recommended Strategic Decision Framework

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Radiolabeled human mass balance studies are crucial for identifying circulating metabolites and understanding drug absorption, excretion, and clearance pathways. Metabolite profiling involves quantifying all drug‐related entities, including parent drug and metabolites in plasma and excreta, using extended liquid chromatography methods coupled with ...
Filip Cuyckens   +21 more
wiley   +1 more source

Permeability of granite from a shallow buried mountain pipe gallery tunnel under unloading confining pressure

open access: yesDeep Underground Science and Engineering, EarlyView.
Triaxial compression tests under unloading confining pressure conditions were conducted to systematically analyze the permeability behavior of granite retrieved from the different classification surrounding rocks. Abstract The rock mass within mountain tunnels undergoes complex changes in permeability, strength, and deformation during tunneling ...
Xiaoyan Zhang   +4 more
wiley   +1 more source

The damage and failure mechanism of prestatically loaded rock during medium‐strain rate cyclic impact loading

open access: yesDeep Underground Science and Engineering, EarlyView.
Based on experimental results and theoretical analysis, an established rock damage accumulation model that comprehensively considers the preapplied static load, impact peak value, impact frequency, and impact times. Abstract To study the rock damage mechanism under high static loading and superimposed medium strain rate cyclic impact loading, a series ...
Wei Wang   +6 more
wiley   +1 more source

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