Closing the loop in nanotheranostics: from <sup>124</sup>I separation to intrinsically radiolabeled platinum nanoparticles for potential PET/CT-guided photothermal therapy. [PDF]
Ghosh S +9 more
europepmc +1 more source
Automated radiosynthesis of 2-[<sup>18</sup>F]BPA for PET-based planning of boron neutron capture therapy (BNCT): rational precursor design, radiofluorination, and characterization of methodology. [PDF]
Paolillo V +4 more
europepmc +1 more source
Multistep Continuous Flow Synthesis of <sup>14</sup>C-Labeled cis/trans-Chrysanthemic Acid. [PDF]
Hashino S +3 more
europepmc +1 more source
Radiochemical purity control of radiolabeled drugs
The risk of using only TLC in the radiochemical purity analysis of a radiolabeled drug is shown on the example of butoprozine. The combination of TLC and HPLC gives much better certainty. In case of impurities, HPLC can be used for purification.
Drenth, BFH, de Zeeuw, RA
openaire +4 more sources
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Chromatographic determination of radiochemical purity
Nuklearmedizin - NuclearMedicine, 2010SummaryThin layer chromatography is well established for quality control of radiopharmaceuticals. A convenient and widely used stationary phase are ITLC SG strips. However, the Pall Corporation stopped manufacturing of the silica gel impregnated glass fibre strips (ITLC SG).
G Wunderlich
exaly +3 more sources
Visualization and Quantification of Radiochemical Purity by Cerenkov Luminescence Imaging
Determination of radiochemical purity is essential for characterization of all radioactive compounds, including clinical radiopharmaceuticals. Radio-thin layer chromatography (radio-TLC) has been used as the gold standard for measurement of radiochemical purity; however, this method has several limitations in terms of sensitivity, spatial resolution ...
Yeong Su Ha +8 more
openaire +3 more sources
Maintaining radiochemical purity of [177Lu]Lu-DOTA-PSMA-617 for PRRT by reducing radiolysis [PDF]
[177Lu]Lu-DOTA-PSMA-617 for PRRT is subject to radiolysis and therefore loses receptor affinity. This will be detrimental for treatment efficacy. In this study optimal quencher(s) (combinations) are determined to maintain radiochemical purity with a ...
Ho Sze Chan, Erik de Blois
exaly +3 more sources
Radiochemical purity of a 99mTc-labeled pyrophosphate techneScan PYP
European Journal of Nuclear Medicine and Molecular Imaging, 1976Otto von Stetten +2 more
exaly +3 more sources

