Results 41 to 50 of about 8,328 (213)

Yttrium-90 for colorectal liver metastasis - the promising role of radiation segmentectomy as an alternative local cure

International Journal of Hyperthermia, 2022
The majority of patients with metastatic colorectal cancer (CRC) to the liver are not amenable to curative-intent surgery or thermal ablation; there is a need for alternative locoregional therapies to control oligometastatic liver disease.
Pouya Entezari, Ahmed Gabr, Riad Salem, Robert J. Lewandowski   +3 more
doaj   +1 more source

Transarterial Radioembolization of Hepatocellular Carcinoma, Liver-Dominant Hepatic Colorectal Cancer Metastases, and Cholangiocarcinoma Using Yttrium90 Microspheres: Eight-Year Single-Center Real-Life Experience

Diagnostics, 2021
Liver tumors are common and may be unamenable to surgery or ablative treatments. Consequently, other treatments have been devised. To assess the safety and efficacy of transarterial radioembolization (TARE) with Yttrium-90 for hepatocellular carcinoma ...
Julie Pellegrinelli, Olivier Chevallier, Sylvain Manfredi, Inna Dygai-Cochet, Claire Tabouret-Viaud, Guillaume Nodari, François Ghiringhelli, Jean-Marc Riedinger, Romain Popoff, Jean-Marc Vrigneaud, Alexandre Cochet, Serge Aho, Marianne Latournerie, Romaric Loffroy   +13 more
doaj   +1 more source

Computed Tomography-Defined Sarcopenia in Outcomes of Patients with Unresectable Hepatocellular Carcinoma Undergoing Radioembolization: Assessment with Total Abdominal, Psoas, and Paraspinal Muscles

Liver Cancer, 2023
Introduction: Sarcopenia is an adverse prognostic factor in patients with liver cirrhosis and hepatocellular carcinoma (HCC). Image-based sarcopenia assessment allows a standardized method to assess abdominal skeletal muscle.
Chih-Horng Wu, Ming-Chih Ho, Chien-Hung Chen, Ja-Der Liang, Kai-Wen Huang, Mei-Fang Cheng, Chih-Kai Chang, Chia-Hung Chang, Po-Chin Liang   +8 more
doaj   +1 more source

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

Advanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu, Peng Li, Zhixiang Lu, Shuqin Xu, Juanjuan Wang, Kai Ma, Haodong Yu, Can Zhou, Hu Chen, Gang Liu, Yi Lyu, Shuang Bai   +11 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

A Supramolecular Approach for Liver Radioembolization

Theranostics, 2018
Hepatic radioembolization therapies can suffer from discrepancies between diagnostic planning (scout-scan) and the therapeutic delivery itself, resulting in unwanted side-effects such as pulmonary shunting. We reasoned that a nanotechnology-based pre-targeting strategy could help overcome this shortcoming by directly linking pre-interventional ...
Spa, S.J., Welling, M.M., Oosterom, M.N. van, Rietbergen, D.D.D., Burgmans, M.C., Verboom, W., Huskens, J., Buckle, T., Leeuwen, F.W.B. van   +8 more
openaire   +5 more sources

Radioembolization with Y-90 resin microspheres of neuroendocrine liver metastases after initial peptide receptor radionuclide therapy [PDF]

, 2019
Purpose Peptide receptor radionuclide therapy (PRRT) and radioembolization are increasingly used in neuroendocrine neoplasms patients. However, concerns have been raised on cumulative hepatotoxicity.
Braat, AJAT, Stothers, Cody C.L., Sze, Daniel D.Y., Flamen, P., Ahmadzadehfar, H., Brown, D.B., Deroose, CM, Flamen, Patrick, Mahvash, A., Deroose, Christophe Michel, Mahvash, Armeen, Frilling, A., Lam, MGEH, Deroose, C.M., Stothers, CL, Sze, D.Y., Kappadath, Srinivas Cheenu, Frilling, Andrea, Lam, Marnix M.G.E.H., Kappadath, SC, Kappadath, S.C., Stothers, C.L., Brown, Daniel, Mahvash, A, Frilling, A, Flamen, P, Lam, M.GE.H., Ahmadzadehfar, Hojjat, Brown, DB, Braat, Arthur A.J.A.T., Ahmadzadehfar, H, Sze, DY, Braat, A.JA.T.   +32 more
core   +1 more source

An Unusual Complication of Transarterial Radioembolization: Hepatic Artery Pseudoaneurysm and its Treatment with Ultrasound-guided Thrombin Injection

The Arab Journal of Interventional Radiology, 2023
Transarterial radioembolization (TARE) is a widely used treatment method for primary liver cancers and metastasis. Although TARE is relatively safe, it may cause liver abscess, failure, nontarget embolization, and vascular complications.
Muhammet Arslan, Halil Serdar Aslan, Burak Sarılar, Aziz Gültekin   +3 more
doaj   +1 more source

Radiotherapy and Immunotherapy In Hepatocellular Carcinoma: Priming the Tumor Immune Microenvironment From Bench To Bedside

Precision Radiation Oncology, EarlyView.
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu, Yang Zhang, Zuomin Wang, Zongjuan Li, Shisuo Du   +4 more
wiley   +1 more source

Radioembolization treatment for liver metastases [PDF]

Współczesna Onkologia, 2017
The liver is an organ that, due to vascularisation and functions, is prone to metastases. Most liver metastases are observed in cases of gastrointestinal cancers in: stomach, colon, gallbladder, and bile ducts. Metastatic lesions are also observed in lung, breast, thyroid, kidney, and pancreatic cancer.
Joanna Kiszka, Bożenna Karczmarek-Borowska   +1 more
openaire   +3 more sources