Results 41 to 50 of about 6,549 (182)

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu   +11 more
wiley   +1 more source

Standards of Practice in Transarterial Radioembolization [PDF]

open access: yesCardioVascular and Interventional Radiology, 2013
Complications (minor/major) A minor complication is a treatment-related adverse event requiring no or minimal therapy with or without overnight hospitalization for observation. A major complication is a treatment-related adverse event requiring further therapy, increased level of care, or prolonged hospitalization [11].
Mahnken, Andreas H.   +4 more
openaire   +3 more sources

Tumor Number and Model for End‐Stage Liver Disease Score as Selection Criteria for Resection or Embolization of Intermediate‐Stage Hepatocellular Carcinoma

open access: yesCancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Tumor and liver‐related factors are well‐known prognostic factors for patients with hepatocellular carcinoma (HCC). The Japanese Society of Hepatology (JSH) guidelines recommend considering liver resection (LR) for patients with multiple tumors and a tumor number ≤ 3.
Yi‐Hao Yen   +5 more
wiley   +1 more source

Case Report: Vasculitis Triggered by SIRT in a Patient With Previously Untreated Cholangiocarcinoma

open access: yesFrontiers in Oncology, 2021
Arising from the biliary tract, cholangiocarcinoma is a rare and aggressive epithelial cancer. According to the primary site, it can be further classified into intrahepatic, perihilar and distal types.
Antonia Stamatiou   +10 more
doaj   +1 more source

Advances and challenges in immunotherapy for intrahepatic cholangiocarcinoma based on the tumour immune microenvironment

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
This review integrates ICC‐specific and broader BTC evidence to define how desmoplastic stroma, immune‐cell crosstalk, metabolic remodelling, and molecular heterogeneity shape immunotherapy response and resistance. It highlights biomarker‐guided, mechanism‐based combinations while emphasizing the limited maturity of ICC‐specific evidence for emerging ...
Mengyao Chen   +5 more
wiley   +1 more source

Radiotherapy and Immunotherapy In Hepatocellular Carcinoma: Priming the Tumor Immune Microenvironment From Bench To Bedside

open access: yesPrecision Radiation Oncology, Volume 10, Issue 3, Page 417-427, September 2026.
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu   +4 more
wiley   +1 more source

Radioembolization treatment for liver metastases [PDF]

open access: yesWspółczesna Onkologia, 2017
The liver is an organ that, due to vascularisation and functions, is prone to metastases. Most liver metastases are observed in cases of gastrointestinal cancers in: stomach, colon, gallbladder, and bile ducts. Metastatic lesions are also observed in lung, breast, thyroid, kidney, and pancreatic cancer.
Joanna Kiszka   +1 more
openaire   +3 more sources

A preference‐integrated optimization system for medical physics shift scheduling

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Clinical shift scheduling for medical physicists is challenging given multidisciplinary roles and competing clinical, research, and service demands. Manual workflows often lack the flexibility and transparency needed for this complex field.
Benjamin S. Rosen   +22 more
wiley   +1 more source

A Supramolecular Approach for Liver Radioembolization

open access: yesTheranostics, 2018
Hepatic radioembolization therapies can suffer from discrepancies between diagnostic planning (scout-scan) and the therapeutic delivery itself, resulting in unwanted side-effects such as pulmonary shunting. We reasoned that a nanotechnology-based pre-targeting strategy could help overcome this shortcoming by directly linking pre-interventional ...
Spa, S.J.   +8 more
openaire   +5 more sources

Management of Satellite Lesions in Hepatocellular Carcinoma: An Updated Review

open access: yesJournal of Surgical Oncology, Volume 134, Issue 2, Page 157-165, August 2026.
ABSTRACT Satellite lesions, defined as microscopic or small macroscopic tumor nodules within 2 cm of a primary hepatocellular carcinoma (HCC), represent early intrahepatic dissemination and are strongly associated with aggressive tumor biology.
Andy Tran   +4 more
wiley   +1 more source

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