The aim of this study was to investigate trends in selective internal radiation therapy (SIRT) for hepatocellular carcinoma (HCC), cholangiocarcinoma (CCC), and liver metastasis in Germany. We analyzed the nationwide German hospital billing database from
Luka Flegar, Christer Groeben
exaly +3 more sources
Elucidating binding hot spots and structural stability in sirtuin family proteins for selective inhibitors: a computational approach [PDF]
BackgroundThe sirtuin (SIRT) family is an NAD+-dependent class III histone deacetylase protein that comprises seven members (SIRT1–7). SIRTs are involved in many cellular pathways, which enable them to act as significant regulators of critical diseases ...
Deepak Sharma, Rajiniraja Muniyan
doaj +2 more sources
A retrospective analysis of Selective Internal Radiation Therapy (SIRT) and chemotherapy for metastatic pancreatic adenocarcinoma [PDF]
Background Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer-related deaths in Australia, with a 5-year survival rate of less than 13%. The liver is the most common site of PDAC metastasis, and is observed in over 50% of cases.
Sue S. Thang +10 more
doaj +2 more sources
Radiation safety aspects of 90Y bremsstrahlung radiation produced from radiation shielding apparatus using the Monte Carlo simulation [PDF]
Selective internal radiation therapy using an 90Y labelled microsphere is increasingly used to treat hepatocellular carcinoma. Based on its properties, 90Y can produce bremsstrahlung radiation which is essential for post-treatment localisation ...
Jumpee Chayanit +4 more
doaj +1 more source
PREVALENCE OF INTESTINAL PARASITIC INFECTION AMONG PRIMARY SCHOOL CHILDREN IN SIRT-LIBYA [PDF]
This study was carried out to determine the prevalence of intestinal parasitic infection in primary school children in eight primary schools in Sirt city, Libya.
Hamed. Kassem +2 more
doaj +1 more source
Yttrium-90 transarterial radioembolization for liver metastases from medullary thyroid cancer
Objectives: Liver metastases occur in 45% of patients with advanced metastatic medullary thyroid cancer (MTC). Transarterial radioembolization (TARE) has been proposed to treat liver metastases (LM), especially in neuroendocrine tumors.
Luciana Puleo +15 more
doaj +1 more source
Purpose: Selective internal radiation therapy (SIRT) is administered to treat tumors of the liver and is generally well tolerated. Although widely adopted for its therapeutic benefits, SIRT is rarely combined with external beam radiation therapy (EBRT ...
Elliot Abbott, DPhil, MSc +6 more
doaj +1 more source
SIRT-1 is required for release of enveloped enteroviruses
Enterovirus D68 (EV-D68) is a re-emerging enterovirus that causes acute respiratory illness in infants and has recently been linked to Acute Flaccid Myelitis.
Alagie Jassey +7 more
doaj +1 more source
Comparative Study of SIRT1 Expression in Hepatitis B Virus, Hepatitis C Virus, and Hepatocellular Carcinoma Patients [PDF]
Background and Aim: The most common form of primary liver cancer in adults is hepatocellular carcinoma (HCC), and it is the most common cause of death in people with cirrhosis.
Ahmed Ibrahim +3 more
doaj +1 more source
Value of hysteroscopy in management of unexplained infertility
Objective: To assess the value of hysteroscopy in unexplained infertility. Methods: 200 infertile women in whom standard infertility investigations revealed no abnormalities were included in the study between January 2009 and December 2013.
Aisha M. Elbareg +3 more
doaj +1 more source

