Results 11 to 20 of about 22,785 (248)
Respiratory ResearchBackground Idiopathic pulmonary fibrosis (IPF) is a debilitating and progressive lung disease of unknown aetiology, characterized by the relentless deposition of fibrotic tissue.
Fabio Perrotta +7 more
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, 2023 Sirt faol moddalar gidrofil va gidrofob qismlardan hosil bo'lgan kimyoviy birikma bo'lib suvda eriganda sirt tarangligiga ta'sir qiladi. Sirt faol moddalar sovun, detarjan, namlovchi moddalar va emulsifikatorlarning umumiy nomi. Sirt faol moddalar shunchaki suyuqlikning sirt tarangligini kamaytiradiga moddalardir.
Bo'ronova .S.H
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CardioVascular and Interventional Radiology, 2022 AbstractSelective internal radiation therapy represents an endovascular treatment option for patients with primary liver malignancies, in different clinical stages. Potential applications of this treatment are in early-stage hepatocellular carcinoma, as a curative option, or in combination with systemic treatments in intermediate and advanced-stages ...
Francesca Romana Ponziani +10 more
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SIRT Family: Biological Functions and Therapeutic Targets. [PDF]
MedComm (2020)Sirtuins (SIRT1–SIRT7) are nicotinamide adenine dinucleotide (NAD + ) dependent deacylases that serves as metabolic sensors, coupling cellular energy status to chromatin structure, mitochondrial function, and ...
Wang JY +9 more
europepmc +2 more sources
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source
Hepatology, EarlyView., 2022 NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger +7 more
wiley +1 more source
Sparse filtered SIRT for electron tomography [PDF]
Pattern Recognition, 2020 Electron tomographic reconstruction is a method for obtaining a three-dimensional image of a specimen with a series of two dimensional microscope images taken from different viewing angles. Filtered backprojection, one of the most popular tomographic reconstruction methods, does not work well under the existence of image noises and missing wedges. This
Chen Mu, Chiwoo Park
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The sirtuin family in health and disease
Signal Transduction and Targeted Therapy, 2022 Sirtuins (SIRTs) are nicotine adenine dinucleotide(+)-dependent histone deacetylases regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in numerous biological processes.
Qi-Jun Wu +15 more
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Sleep, Sirtuin 1 and Alzheimer’s disease: A review
Aging Brain, 2022 Sleep plays a major role in brain health, and cognition. Disrupted sleep is a well-described symptom of Alzheimer’s disease (AD). However, accumulating evidence suggests suboptimal sleep also increases AD risk. The deacetylase Sirtuin 1 (Sirt 1), encoded
Mehrane Mehramiz +3 more
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Potential Antiaging Effects of DLBS1649, a Centella asiatica Bioactive Extract
Journal of Experimental Pharmacology, 2021 Agung H Karsono,1 Olivia M Tandrasasmita,1 Guntur Berlian,1 Raymond R Tjandrawinata2,3 1Section of Molecular Pharmacology, Research Innovation and Invention, Dexa Laboratories of Biomolecular Sciences, Dexa Medica, Cikarang, West Java 17550, Indonesia ...
Karsono AH +3 more
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