Results 31 to 40 of about 22,785 (248)
SIRT-2 inhibition reverses endotoxin tolerance in RAW cells.
, 2016 A: SIRT-2 inhibitor AK-7 enhanced LPS induced cytokine response in sensitive cells. RAW cells were pre-treated with vehicle (DMSO) or AK-7 (25uM) for 1h before the stimulation with normal saline or LPS (100ng/ml) for 4h and TNF-α mRNA expression levels ...
Xianfeng Wang (120153) +6 more
core +1 more source
Applied SciencesThis study compares various methodologies for lung dosimetry in radioembolization using Monte Carlo (MC) simulations. A voxelized anthropomorphic phantom, created from a real patient’s CT scan, preserved the actual density distribution of the lungs. Lung
Edoardo d’Andrea +4 more
doaj +1 more source
SIRT-2 inhibition during sepsis repressor/ hypo-inflammatory phase improves survival.
, 2016 We examined the effect of SIRT-1 (EX-527) and SIRT-2 (AK-7) inhibitors vs. vehicle treatment during the hypo-inflammatory phase of sepsis on 7-day survival in ob/ob mice.
Xianfeng Wang (120153) +6 more
core +1 more source
SIRT-2 inhibition in ob/ob septic mice restores repressed microvascular leukocyte adhesion.
, 2016 A: SIRT-2 inhibition during hypo-inflammation enhances leukocyte adhesion in ob/ob: mice with sepsis: ob/ob-septic mice were treated with Vehicle or AK-7 during hypo-inflammatory phase of sepsis, challenged with either normal saline (NS) or LPS and ...
Xianfeng Wang (120153) +6 more
core +1 more source
Federated MobileNetV2 with ensemble meta-learning for privacy-preserving brain tumor classification
Scientific ReportsThe identification of brain tumors from MRI images is very crucial for the selection of an appropriate treatment. However, the existing solution has issues with privacy and data sharing. To address this challenge, this paper proposes the use of federated
Menali Paul +4 more
doaj +1 more source
Radioembolization for neuroendocrine tumors: procedure, application and clinical outcomes
Endocrine OncologyNeuroendocrine liver metastases significantly affect patient prognosis and quality of life due to their symptomatic burden and challenging management. Besides conventional systemic therapies, liver-directed therapies improve patient outcomes in patients ...
Li Shen Ho +3 more
doaj +1 more source
Deposition, diagenesis, and reservoir development of the Cretaceous Lidam formation, SE Sirt Basin, Libya. [PDF]
, 2007 This study concentrates on the deposition, diagenesis and reservoir characteristics of the Upper Cretaceous (Cenomanian) Lidam Formation. Core, petrography and geochemical data were studied from five wells (P3-97, N6-97, R1-97， 3V1-59E, and 3V3-59E) in ...
Abugares, Miloud M.
core
Advanced Science, EarlyView.Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang +12 more
wiley +1 more source
Hydrocarbon prospectivity to the north-west of the assumood field, Sirt Basin, Libya [PDF]
, 2000 The area of study covers parts of the Assumood Ridge and the Wadayat Trough in the Sirt Basin, onshore Libya. The area is surrounded on three sides by gas fields producing from the Lower Oligocene Arida Formation, the Middle Eocene Gialo Formation and ...
Salem, Amjed Ahmed Ben
core
DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury
Advanced Science, EarlyView.This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang +7 more
wiley +1 more source