Results 21 to 30 of about 22,785 (248)

SIRT 2.0: Smart interactive revision tool [PDF]

open access: yes, 2022
Smart Interactive Revision Tool (SIRT 2.0) is a new approach to perform revision in an interesting up to current situation that align to STEM education.
Zainal, Muhammd Faiz   +4 more
core  

Elucidation of SIRT-1/PGC-1α-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease

open access: yesLipids in Health and Disease, 2021
Background Nonalcoholic fatty liver disease (NAFLD) can lead to chronic liver diseases associated with mitochondrial damages. However, the exact mechanisms involved in the etiology of the disease are not clear.
Yan Jiang   +6 more
doaj   +1 more source

Suitability of DNN-based vessel segmentation for SIRT planning

open access: yes, 2023
233240Purpose: The segmentation of the hepatic arteries (HA) is essential for state-of-the-art pre-interventional planning of selective internal radiation therapy (SIRT), a treatment option for malignant tumors in the liver.
Schenk, Andrea   +4 more
core   +1 more source

Non-Invasive Imaging Biomarkers to Predict the Hepatopulmonary Shunt Fraction Before Transarterial Radioembolization in Patients with Hepatocellular Carcinoma

open access: yesJournal of Hepatocellular Carcinoma, 2023
Charlie Alexander Hamm,1,2,* Felix Busch,1,3,* Anna Pöhlmann,4 Annabella Shewarega,5 Yubei He,1 Robin Schmidt,1 Han Xu,1 Gero Wieners,1 Bernhard Gebauer,1 Lynn Jeanette Savic1,2 1Department of Radiology, Campus Virchow-Klinikum, Charité ...
Hamm CA   +9 more
doaj  

Effect of high-dose glucocorticoids on markers of inflammation and bone metabolism in patients with primary glomerular disease

open access: yesKidney & Blood Pressure Research, 2022
Background: Glucocorticoids are one of the most commonly used drugs for treatment of inflammatory and autoimmune diseases. Sirtuin-1 (SIRT-1) belongs to family of proteins involved in protection against inflammation and oxidative stress.
Katarzyna Pęczek, Michał Nowicki
doaj   +1 more source

Abnormal expression of SIRTs in psoriasis: Decreased expression of SIRT 1-5 and increased expression of SIRT 6 and 7

open access: yesInternational Journal of Molecular Medicine, 2019
The prevalence of psoriasis is increasing, and poses a serious risk to human health and quality of life. Psoriasis, a chronic immune‑mediated skin disease with epidermal hyperkeratosis and parakeratosis, is associated with numerous complications, including metabolic syndromes that are regulated by sirtuins (SIRTs) via deacetylation.
Fan, Xiaojing   +7 more
openaire   +3 more sources

Sparse-View Neutron CT Reconstruction Using a Modified Weighted Total Difference Minimization Method

open access: yesApplied Sciences, 2021
Indirect neutron imaging is an effective method for nondestructive testing of spent nuclear fuel elements. Considering the difficulty of obtaining experimental data in a high-radiation environment and the characteristic of high noise of neutron images ...
Yapeng Wu   +7 more
doaj   +1 more source

The SIRT 3 Expression Profile is Associated with Pathological and Clinical Outcomes in Human Breast Cancer Patients

open access: yesCellular Physiology and Biochemistry, 2014
Aims: To investigate the association of Sirtuin 3 (SIRT 3) expression between the clinical characteristics and prognosis in breast cancer patients. Methods: 308 female patients with histologically confirmed breast cancer were enrolled in this study.
Shaozhong He   +5 more
doaj   +1 more source

SIRT Was Given Short Shrift [PDF]

open access: yesDeutsches Ärzteblatt international, 2014
The acronym SIRT stands for selective internal radiation therapy. At the present time, 19 completed studies and 20 ongoing studies are registered in ClinicalTrials.gov. Three of the studies are randomized multicenter phase III studies (SORAMIC, SIRveNIB, SARAH) at stages Child-Pugh A–B, whose follow-up results are expected for 2015–2017.
openaire   +2 more sources

MicroRNA-181a-5p regulates inflammatory response of macrophages in sepsis

open access: yesOpen Medicine, 2019
The aim of this study was to evaluate the role of miR-181a-5p in sepsis, and to further explore the molecular mechanism. RAW 264.7 cells were stimulated with 1 μg/ml LPS for 4 hours.
Huang Zheng, Xu Hang
doaj   +1 more source

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