Results 91 to 100 of about 15,914 (251)
Melanocortin 1 receptor targeted imaging of melanoma with gold nanocages and positron emission tomography [PDF]
, 2018 Purpose: Melanoma is a lethal skin cancer with unmet clinical needs for targeted imaging and therapy. Nanoscale materials conjugated with targeting components have shown great potential to improve tumor delivery efficiency while minimizing undesirable ...
Black, Kvar +8 more
core +2 more sources
Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy
Advanced NanoBiomed Research, Volume 5, Issue 10, October 2025.This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei +3 more
wiley +1 more source
Effect of Small-Molecule-Binding Affinity on Tumor Uptake In Vivo: A Systematic Study Using a Pretargeted Bispecific Antibody [PDF]
, 2012 Small-molecule ligands specific for tumor-associated surface receptors have wide applications in cancer diagnosis and therapy. Achieving high-affinity binding to the desired target is important for improving detection limits and for increasing ...
Frangioni, John V. +4 more
core +1 more source
Cancer Communications, Volume 45, Issue 10, Page 1203-1228, October 2025.Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan +11 more
wiley +1 more source
Pharmaceuticals, 2015 Faced with the novelty of a 212Pb-labeled monoclonal antibody (mAb) for clinical translation, concerns were expressed by the Food and Drug Administration (FDA) regarding 212Pb prematurely released from the mAb-chelate conjugate.
Diane E. Milenic +7 more
doaj +1 more source
Targeted therapy in nuclear medicine—current status and future prospects [PDF]
, 2017 In recent years, a number of new developments in targeted therapies using radiolabeled compounds have emerged. New developments and insights in radioiodine treatment of thyroid cancer, treatment of lymphoma and solid tumors with radiolabeled monoclonal ...
Bodei, L. +6 more
core
Thiacalix[4]arene derivatives bearing imidazole units : a ditopic hard/soft receptor for Na⁺ and K⁺/Ag⁺ with an allosteric effect and a reusable extractant for dichromate anions [PDF]
, 2016 © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Two novel receptors 5,11,17,23-tetra-tert-butyl-25,27-bis[(ethoxycarbonyl)methoxy]-26,28-bis-[1-methyl-(imidazole)meth-oxy] -2,8,14,20-tetra-thiacalix[4]arene (L1) and 5,11,17,23-tetra-tert-butyl-25,27 ...
Akgemci +40 more
core +4 more sources
Radioimmunotherapy and colorectal cancer
British Journal of Surgery, 2005 AbstractBackgroundDespite the success of radioimmunotherapy (RIT) using radiolabelled monoclonal antibodies (Mabs) directed against tumour-associated antigens in the treatment of non-Hodgkin's lymphoma, therapeutic success in solid tumours has been modest. In the past decade, a dozen Mabs have been investigated clinically for their potential usefulness
Koppe, M.J. +3 more
openaire +4 more sources
Targeting gut microbiota and metabolites in cancer radiotherapy
Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.Radiotherapy (RT) efficacy and toxicity are influenced by gut microbiota and their metabolites. This review explores how probiotics, prebiotics, and microbial byproducts (e.g., short‐chain fatty acids [SCFAs]) mitigate radiation damage and enhance tumour radiosensitivity.
Shuling Ma +6 more
wiley +1 more source